تاثیر یک دوره ویبریشن کل بدن بر افسردگی، سروتونین و نوراپی نفرین سرم زنان یائسه با کم کاری تیروئید

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 گروه تربیت بدنی و علوم ورزشی، دانشکده علوم انسانی، دانشگاه آیت الله العظمی بروجردی (ره)، بروجرد، ایران.

2 گروه تربیت بدنی، دانشکده علوم انسانی، دانشگاه فنی و حرفه ای، تهران،ایران.

10.22049/jahssp.2023.28185.1528

چکیده

هدف: کم کاری تیروئید به­همراه یائسگی اثر مضاعفی بر افسردگی زنان یائسه دارد که فعالیت ورزشی با افزایش میانجی­های عصبی منجر به بهبود خلق و خو می­شود. هدف از این مطالعه تعیین تاثیر یک دوره ویبریشن کل بدن بر افسردگی، سروتونین و نوراپی نفرین زنان یائسه با کم کاری تیروئید بود. روش شناسی: در این مطالعه نیمه­تجربی 20 زن یائسه با کم کاری تیروئید 46 تا 57 ساله شهرستان خرم آباد انتخاب و به دو گروه 10 نفره: کنترل(C)  و تمرین ویبریشن کل بدن(V) ، تقسیم شدند. گروهV ، این تمرینات را به مدت 12 هفته و سه بار در هفته، با فرکانس 30 تا 50 هرتز،  با دامنه یک تا دو میلی­متر با اعمال 20 تا 30 دقیقه ویبریشن 5 تا 15 دقیقه تمرین اندام فوقانی و تحتانی را انجام دادند. در دو مرحله شروع و پایان مطالعه سطح سروتونین و نوراپی نفرین سرم خون با استفاده از روش الایزا، میزان افسردگی با استفاده از پرسشنامه بک، درصد چربی بدن، شاخص توده بدنی و وزن بدن مورد سنجش قرار گرفت. با توجه به طبیعی بودن توزیع داده­ها از روش­های آماری تی مستقل و کوواریانس، در سطح معناداری 05/0 تجزیه ‌و تحلیل استفاده شد. یافته‌ها: 12 هفته تمرین ویبریشن کل بدن در گروه V باعث افزایش معنادار سطح سرمی سروتونین (001/0P=)، نوراپی نفرین (001/0P=) و کاهش افسردگی (018/0P=) نسبت به گروه کنترل شد. همچنین کاهش معناداری در میزان درصد چربی بدن (041/0P=)، شاخص توده بدن (044/0P=) و وزن (047/0P=) دیده شد. نتیجه‌گیری: به نظر می‌رسد که تمرینات ویبریشن احتمالا از طریق افزایش میزان سروتونین و نوراپی نفرین سرم موجب کاهش افسردگی زنان یائسه مبتلا به کم کاری تیروئید می­شود.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of a Whole Body Vibration Course on Depression, Serotonin and Norepinephrine Indices in Postmenopausal Women with Hypothyroidism

نویسندگان [English]

  • Amir Khosravi 1
  • Sedigheh Taherzadeh 2
1 Department of Physical Education and Exercise Science، Faculty of Humanities, Ayatollah Ozma Borujerdi University, Borujerd, Iran.
2 Department of Physical Education, Faculty of Human Sciences, Technical and Vocational University (TVU), Tehran, Iran.
چکیده [English]

Aim:  hypothyroidism in addition to menopause has a double effect on depression in postmenopausal women, and sports activity improves mood by increasing neurotransmitters. The aim of this study was to determine the effect of a period of whole body vibration course on depression, the levels of serotonin and norepinephrine indices in postmenopausal women with hypothyroidism. Methods: In this semi experimental study, 20 postmenopausal women with hypothyroidism aged 46 to 57 were selected from Khorramabad city and divided into two groups of 10: control (C) and whole body vibration training (V). Group V performed these exercises for 12 weeks and three times a week, with a frequency of 30 to 50 Hz, with a range of 1 to 2 mm, applying 20 to 30 minutes of vibration and 5 to 15 minutes of upper and lower limb training. At the beginning and end of the study, blood serum serotonin and norepinephrine levels were measured using the ELISA method, depression was measured using the Beck questionnaire, body fat percentage, body mass index, and body weight. Due to the normality of data distribution, independent t and covariance statistical methods were used for analysis at a significance level of 0.05. Results: 12 weeks of whole body vibration training in group V significantly increased the serum levels of serotonin (P=0.001), norepinephrine (P=0.001) and decreased depression (P=0.018) compared to the control group. There was also a significant decrease in body fat percentage (P=0.041), body mass index (P=0.044) and weight (P=0.047). Conclusions:  It seems that vibration training may reduce depression in postmenopausal women with hypothyroidism by increasing serum serotonin and norepinephrine levels.

کلیدواژه‌ها [English]

  • Vibration
  • Serotonin
  • Norepinephrine
  • Hypothyroidism
  • Depression

مراجع

  1. 1. Khosravi A, Taherzadeh S. The Effect of a Whole Body Vibration Period on Serum BDNF Levels in Obese Postmenopausal Women. Journal of Applied Health Studies in Sport Physiology. 2022;9(2):81-92.[ In Persian]
  2. 2. Baksi S, Pradhan A. Thyroid hormone: sex-dependent role in nervous system regulation and disease. Biology of sex differences. 2021;12(1):1-13.
  3. 3. Baharloo S, Taghiyan F, Hedayati M. Effect of aerobic exercise on glucose, insulin and insulin resistance in subclinical hypothyroidism overweight-obese women. Razi Journal of Medical Sciences. 2014;21(125):75-84.
  4. 4. Kennedy SH, Dickens SE, Eisfeld BS, Bagby RM. Sexual dysfunction before antidepressant therapy in major depression. Journal of affective disorders. 1999;56(2-3):201-8.
  5. 5. Ayati S, & Aboutorabi, R., & Vahid Roudsari, F., & Torabizadeh, A., & Shakeri, M., Thyroid Dysfunction in Perimenopausal Women. Journal of Medical Council of IRI. 2009;26(4):504-9. [ In Persian]
  6. 6. Bauer M, Heinz A, Whybrow P. Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain. Molecular psychiatry. 2002;7(2):140-56.
  7. 7. Hall S-JE. Guyton and Hall Textbook of Medical Physiology E-Book, livre ebook. 2010.
  8. 8. Mueller AK, Fuermaier AB, Koerts J, Tucha L. Stigma in attention deficit hyperactivity disorder. ADHD attention deficit and hyperactivity disorders. 2012;4(3):101-14.
  9. 9. Magda SM, Abdel-Latif OS, Gharib O. Effect of Whole Body Vibration on Obese Hypothyroid Postmenopausal Women. The Medical Journal of Cairo University. 2021;89(September):1951-60.
  10. 10. Aksoy D. Effect of Whole Body Vibration Training on Depression Level. Journal of Education and Training Studies. 2019;7(3).
  11. 11. Wunram HL, Hamacher S, Hellmich M, Volk M, Jänicke F, Reinhard F, et al. Whole body vibration added to treatment as usual is effective in adolescents with depression: a partly randomized, three-armed clinical trial in inpatients. European child & adolescent psychiatry. 2018;27(5):645-62.
  12. 12. Koike Y, Hoshitani M, Tabata Y, Seki K, Nishimura R, Kano Y. Effects of vibroacoustic therapy on elderly nursing home residents with depression. Journal of Physical Therapy Science. 2012;24(3):291-4.
  13. 13. Di Loreto C, Ranchelli A, Lucidi P, Murdolo G, Parlanti N, De Cicco A, et al. Effects of whole-body vibration exercise on the endocrine system of healthy men. Journal of endocrinological investigation. 2004;27(4):323-7.
  14. 14. Simão AP, Mendonça VA, Avelar NCP, da Fonseca SF, Santos JM, de Oliveira ACC, et al. Whole body vibration training on muscle strength and brain-derived neurotrophic factor levels in elderly woman with knee osteoarthritis: A randomized clinical trial study. Frontiers in physiology. 2019;10:756.
  15. 15. Jackson AS, Pollock ML. Generalized equations for predicting body density of men. British journal of nutrition. 1978;40(3):49504-7.
  16. 16. Ma C, Liu A, Sun M, Zhu H, Wu H. Effect of whole-body vibration on reduction of bone loss and fall prevention in postmenopausal women: a meta-analysis and systematic review. Journal of orthopaedic surgery and research. 2016;11(1):24.
  17. 17. Kaviyani H. Study of validity and reliability of hospital scale on anxiety and depression, general health questionnaire mood adjectives checklist and Beck depression inventory in clinical and nonclinical populations. Journal of Tehran University of Medical Sciences. 2009;66(2):136-40.[ In Persian]
  18. 18. Taherzadeh S, Mogharnasi M, Kayedi A, Rasoulian B. The Effect of 6 Weeks of Aerobic Exercise and Aqueous Extract of Caraway Seed on Expression of FNDC5 Gene and Serum Irisin Level in Obese Male Rats. Sport Physiology & Management Investigations. 2021;13(1):91-103. [ In Persian]
  19. 19. Shamsi M, Rahimi MR. The Effect of Eight Weeks of Resistance Training with Green Tea Extract Supplement On Serum Levels of Adiponectin and Pentraxin-3 In Obese Men. Journal of Applied Health Studies in Sport Physiology. 2021;8(2):94-101.
  20. 20. Ariizumi M, Yamaguchi Y, Okada A. Effect of local vibration on the brain monoamines of rats. Scandinavian Journal of Work, Environment & Health. 1986:435-7.
  21. 21. Saran T, Turska M, Kocki T, Zawadka M, Zieliński G, Turski WA, et al. Effect of 4-week physical exercises on tryptophan, kynurenine and kynurenic acid content in human sweat. Scientific reports. 2021;11(1):1-7.
  22. 22. Mikheev AA. Research on the dynamics of the hormonal status of athletes in a series of vibration and traditional training exercises. 中国体育科技. 2009.
  23. 23. Fathi Zadeh M, alimoradi s. The Effect of Aerobics Exercise on Depression, Anxiety, and Stress in Women With Subclinical Hypothyroidism. Nursing and Midwifery Journal. 2019;17(9):749-57.[In Persian]
  24. 24. Wehrle E, Liedert A, Heilmann A, Wehner T, Bindl R, Fischer L, et al. The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice. Disease models & mechanisms. 2015;8(1):93-104.
  25. 25. Bansal R, Aggarwal N. Menopausal hot flashes: a concise review. Journal of mid-life health. 2019;10(1):6.
  26. 26. Wei Q-S, Huang L, Chen X-H, Wang H-B, Sun W-S, Huo S-C, et al. Effect of Whole Body Vibration Therapy on Circulating Serotonin Levels in an Ovariectomized Rat Model of Osteoporosis. Iranian Journal of Basic Medical Sciences. 2014;17(1):62.
  27. 27. Torabi F, Aghayari A, Daneshpour M, Ramezankhani A. A Comparison of Serum Serotonin Level and Some Physical Fitness Factors in Active Elderly. Journal of Sport Biosciences. 2017;473-87(4):7.[In Persian]
  28. 28. Debidi Roshan Wali Elah MZ. The Study of Changes in Norepinephrine Metabolism and Hamilton Scale Following Regular Aerobic Exercise in Water and Their Relationship in the Moderate Depressed Girls. Research in Sport Medicine & Technology. 2011;8-21(1):9.[In Persian]
  29. 29. Wang J, Chen X, Zhang N, Ma Q. Effects of exercise on stress-induced changes of norepinephrine and serotonin in rat hippocampus. Chin J Physiol. 2013;56(5):245-52.
  30. 30. Dubuisson D, Dennis SG. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. pain. 1977;4:161-74.
  31. 31. Leonard BE. Stress, norepinephrine and depression. Journal of psychiatry & neuroscience: JPN. 2001;26(Suppl):S11.
  32. 32. Hashimoto R, Ozaki N, Ohta T, Kasahara Y, Kaneda N, Nagatsu T. Plasma tetrahydrobiopterin levels in patients with psychiatric disorders. Neuropsychobiology. 1990;23(3):140-3.
  33. 33. Anderson D, Wilkinson A, Abou‐Saleh M, Blair J. Recovery from depression after electroconvulsive therapy is accompanied by evidence of increased tetrahydrobiopterin‐dependent hydroxylation. Acta Psychiatrica Scandinavica. 1994;90(1):10-3.
  34. 34. Di Giminiani R, Rucci N, Capuano L, Ponzetti M, Aielli F, Tihanyi J. Individualized whole-body vibration: neuromuscular, biochemical, muscle damage and inflammatory acute responses. Dose-Response. 2020;18(2):1559325820931262.
  35. 35. Bliss EL, Ailion J, Zwanziger J. Metabolism of norepinephrine, serotonin and dopamine in rat brain with stress. Journal of Pharmacology and Experimental Therapeutics. 1968;164(1):122-34.
  36. 36. Weiss JM, Glazer HI, Pohorecky LA, Brick J, Miller NE. Effects of chronic exposure to stressors on avoidance-escape behavior and on brain norepinephrine. Psychosomatic medicine. 1975;37(6):522-34.
  37. 37. Chobineh Z, Banitalebi E, Bagheri L, Azimian E. Comparing effects of two alternating order combination exercises (strength and endurance) on Blood pressure, Catecholamine's and Body composition in Overweight Postmenopausal Women. Iranian Journal of Rehabilitation Research in Nursing. 2015;2(1):66-78.[In Persian]
  38. 38. Ariizumi M, Okada A. Effects of whole body vibration on biogenic amines in rat brain. Occupational and Environmental Medicine. 1985;42(2):133-6.
  39. 39. Dąbrowska J, Dąbrowska-Galas M, Rutkowska M, Michalski BA. Twelve-week exercise training and the quality of life in menopausal women–clinical trial. Menopause Review/Przegląd Menopauzalny. 2016;15(1):20-5.
مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 10، شماره 2
مهر 1402
صفحه 40-53

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  • تاریخ دریافت: 23 تیر 1402
  • تاریخ بازنگری: 18 مرداد 1402
  • تاریخ پذیرش: 18 شهریور 1402

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