عنوان مقاله [English]
Aim: Obesity and being overweight are the main causes of metabolic disorders like diabetes, hypertension, and cardiovascular disease. Adropine mediates exercise-induced changes and, in parallel, reduces the oxidation of muscle fatty acids, which can lead to a reduction in exercise-induced vascular stiffness. Therefore, the aim of this study was to compare and evaluate the effects of intense periodic aerobic exercise and intense intermittent exercise on adropine serum levels and their relationship with the lipid profile in overweight men. Methods: A total of 24 overweight young men, ranging in age from 25 to 35 years, were randomly selected as a sample in 3 groups, with 8 people each for aerobic exercise, intense intermittent exercise, and control. Both types of exercises were performed for 6 weeks, 3 sessions per week, and 45 to 65 minutes per session. Before and after the training interventions, blood samples were collected to measure and calculate the adropine serum levels and lipid profile in the 12-hour fasting state. Results: 6 weeks of moderate-intensity aerobic exercise and intense interval exercise resulted in a significant increase in adropine (P=0.006) and HDL (P=0.001) as well as a significant decrease in triglycerides (P=0.002), cholesterol (P=0.017), LDL(P=0.001) of overweight men .Also, there was a significant negative relationship between changes in adropine with triglycerides(P=0.002), cholesterol(P=0.017), and LDL(P=0.001), and a significant positive relationship between changes in adropine and HDL. Conclusions: Aerobic exercise and interval exercise improving the lipid profile in overweight men, by reducing the lipid profile, it can be said that risk of cardiovascular disease is reduced. Adropine appears to play a role in these exercise induced changes. Therefore, special attention should be paid to the mediator role of adropine in these changes resulting from exercise.
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