تاثیر 8 هفته تمرین مقاومتی شدید بر سطوح سرمی پرپتین،آدروپین و هورمون انسولین در مردان چاق مبتلا به پیش دیابت

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 دانشجوی کارشناسی ارشد فیزیولوژی ورزشی و تندرستی، دانشکده علوم انسانی، دانشگاه کاشان، کاشان، ایران

2 دانشیار فیزیولوژی ورزشی دانشگاه کاشان

3 دکترای تخصصی فیزیولوژی ورزشی دانشگاه محقق اردبیلی

10.22049/jahssp.2024.29330.1621

چکیده

هدف: سایتوکاین­های پرپتین و آدروپین در متابولیسم انرژی نقش تنظیمی دارند، اما مکانیزم آنها در افراد چاق پیش­دیابتی در پاسخ به ورزش به خوبی مشخص نیست. هدف از تحقیق حاضر بررسی تاثیر 8 هفته تمرین مقاومتی دایره­ای شدید بر سطوح سرمی پرپتین و آدروپین در مردان چاق مبتلا به پیش دیابت بود. روش‌ شناسی: در این مطالعه نیمه‌تجربی 30 نفر از مردان چاق پیش‌دیابتی با میانگین (سن: 57/4±76/37، وزن: 87/4±23/98، BMI: 29/1±87/30) به صورت تصادفی به دو گروه تجربی و کنترل (هر گروه 15 نفر)، تقسیم شدند. گروه تجربی به مدت 8 هفته و هر هفته سه جلسه به مدت 60 دقیقه در برنامه HIRT با شدت 80 تا 85 درصد یک تکرار بیشینه شرکت کردند. سطوح سرمی آدروپین، پرپتین و انسولین در دو نوبت پیش و پس آزمون اندازه‌گیری شد. تحلیل داده‌ها با استفاده از آزمون t مستقل و t زوجی در سطح معناداری 05/0>P  انجام شد. یافته‌ها: مقادیر پرپتین (002/0=P)، انسولین (007/0=P)، گلوکز (001/0=P)، مقاومت به انسولین (001/0=P)، در گروه تجربی نسبت به گروه کنترل کاهش معناداری یافت، در حالیکه سطح آدروپین (003/0=P) افزایش معناداری نشان داد. نتایج t زوجی کاهش معنادار پرپتین (001/0=P، 20/0- درصد)، افزایش آدروپین (001/0=P، 5/21 درصد)، و کاهش شاخص­های مرتبط با دیابت (انسولین (001/0=P، 5/17- درصد)، گلوکز (001/0=P، 1/19- درصد) و مقاومت به انسولین (001/0=P، 5/17- درصد)  در پاسخ به پروتکل تمرین را نشان داد (05/0>P).  نتیجه‌گیری: احتمالاً تمرینات HIRT می­تواند بر شاخص­های آدروپین، پرپتین و برخی شاخص­های دیابت و ترکیب بدن در مردان چاق پیش­دیابتی تاثیر مفیدی داشته باشد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of 8 weeks of intense resistance training on serum levels of perpetin, atropine and insulin hormone in obese men with prediabetes

نویسندگان [English]

  • Hani Hudwan 1
  • mohammad javad pourvaghar 2
  • mohammad ebrahim bahram 3
1 Master's student in sports physiology and health, Faculty of Humanities, University of Kashan, Kashan, Iran
2 Associate Professor of Sports Physiology, Faculty of Humanities, Kashan of University, Kashan, Iran
3 Ph.D in Exercise physiology, educational sciences and psychology, University of Mohaghegh Ardabili, Iran
چکیده [English]

Aim: Cytokines preptin and adropin have a regulatory role in energy metabolism, but their mechanism in response to exercise in obese prediabetic subjects is not well understood. The aim of this study was to investigate the effect of 8 weeks of intense circuit resistance training on serum levels of preptin and adropin in obese men with prediabetes. Method: In this semi-experimental study, 30 obese prediabetic men were randomly divided into two experimental and control groups (15 people in each group). The experimental group participated in the HIRT program with an intensity of 80-85% of one maximum repetition for 8 weeks and three sessions for 60 minutes each week. Serum levels of adropin, preptin, and insulin were measured on two occasions before and after the test. Data analysis was done using independent t test and paired t test at a significance level of P<0.05. Results: The levels of preptin (P=0.002), insulin (P=0.007), glucose (P=0.001), insulin resistance (P=0.001) decreased significantly in the experimental group compared to the control group. While the level of adropin showed a significant increase (P=0.003). Paired t results showed a significant decrease in preptin (P=0.001, -0.20 percent), an increase in adropin (P=0.001, 21.5 percent), and a decrease in indicators related to diabetes insulin (P = 0.001) P, -17.5 percent), glucose (P=0.001, -19.1 percent) and insulin resistance (P=0.001, -17.5 percent) in response to the exercise protocol (P<0.05). Conclusion: Probably, HIRT exercises can have a beneficial effect on adropin, preptin and some diabetes indicators and body composition in pre-diabetic obese men.

کلیدواژه‌ها [English]

  • High-Intensity Circuit Training
  • Preptin
  • Adropin
  • Prediabetes
  • Insulin Resistance

مراجع

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  • تاریخ دریافت: 21 دی 1402
  • تاریخ بازنگری: 26 اسفند 1402
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