ارتباط تغییرات سختی شریانی متعاقب مصرف گلوکز و فعالیت هوازی با سطوح پایه قندخون (FBS) و مالون‌دی‌آلدئید (MDA) در زنان غیرفعال

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 استادیار گروه تربیت‌بدنی و علوم ورزشی، دانشکده تربیت بدنی، دانشگاه صنعتی شاهرود، شاهرود، ایران.

2 کارشناس ارشد فیزیولوژی ورزشی، دانشکده تربیت بدنی، دانشگاه صنعتی شاهرود، شاهرود، ایران.

3 دانشیار گروه تربیت‌بدنی و علوم ورزشی، دانشکده تربیت بدنی، دانشگاه صنعتی شاهرود، شاهرود، ایران.

10.22049/jahssp.2023.28706.1560

چکیده

هدف: با عنایت به اهمیت فاکتورهای فشار اکسایشی و همچنین قند خون در سلامت و عملکرد عروقی، این تحقیق با هدف بررسی ارتباط سطوح پایه مالون‌دی‌آلدئید (MDA) و قند‌خون‌ناشتایی (FBS) با شاخص‌های سختی‌شریانی (شامل: شاخص عروقی قلبی- مچ پایی (CAVI) و شاخص مچ پایی بازویی (ABI))، متعاقب مصرف گلوکز و فعالیت ورزشی هوازی انجام شد. روش‌شناسی: این پژوهش به صورت نیمه تجربی روی 40 آزمودنی زن غیرفعال در رده سنی ۲۰ تا ۴۵ سال شهرستان شاهرود انجام گرفت. بعد از ۱۲ ساعت ناشتایی نمونه‌خون وریدی از آزمودنی‌ها برای اندازه‌گیری FBS و MDA و نیز اندازه‌گیری‌های وزن, قد, ترکیب بدن و سختی‌شریانی (CAVI و ABI) پایه انجام شد؛ در ادامه ۳۰ دقیقه فعالیت استقامتی حاد با ۶۵٪ حداکثر ضربان قلب ذخیره بر روی نوار‌گردان اجرا شد. آزمودنی‌ها ۷۵ گرم گلوکز محلول در ۲۲۵ میلی‌لیتر آب را پس از 30 دقیقه از اتمام فعالیت مصرف کردند و پس از آن یک ساعت دیگر استراحت غیر فعال انجام شد؛ در انتها سختی‌شریانی و قند‌خون مجدد اندازه‌گیری شد. یافته‌ها: بین سطوح پایه MDA و FBS با سطوح پایه  CAVIارتباط معنی‌داری وجود دارد (001/0p=)، اما بین سطوح پایه MDA و FBS با تغییرات  CAVIبعد از فعالیت و مصرف گلوکز ارتباط معنی‌داری وجود نداشت (05/0p˃). همچنین سطوح پایه MDA و FBS با شاخص  ABIدر هر دو سطح پایه (001/0p=) و نیز تغییرات این شاخص در مرحله دوم اندازه‌گیری پس از مداخله به نسبت سطوح استراحت (003/0p=) ارتباط معناداری داشتند. نتیجه‌گیری: بطور کل می‌توان نتیجه گرفت سختی‌شریانی پایه با سطوح پایه MDA و FBS ارتباط دارد اما در مواجه با شرایط بر هم زننده هموستاز هم‌چون فعالیت ورزشی استقامتی با شدت متوسط و مصرف گلوکز تنها پاسخ شاخص سختی شریانی محیطی (ABI) با این موارد ارتباط دارد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Correlation between arterial stiffness changes following glucose ingestion and aerobic exercise with baseline levels of blood sugar factors (FBS) and Malondialdehyde (MDA) in inactive women

نویسندگان [English]

  • Adel Donyaei 1
  • Mehrnegar rojhannezhad 2
  • Farhad Gholami 3
1 Assistant Professor, Department of Physical Education and Sport Sciences, Faculty of Physical Education, Shahrood University of Technology, Shahrood, Iran.
2 MSc of Exercise Physiology, Faculty of Physical Education, Shahrood University of Technology, Shahrood, Iran.
3 Associate Professor, Department of Physical Education and Sport Sciences, Faculty of Physical Education, Shahrood University of Technology, Shahrood, Iran.
چکیده [English]

Aim:      The purpose of this research was to investigate the relationship between basal levels of malondialdehyde (MDA) and fasting blood glucose (FBS) with arterial stiffness indices (including cardiovascular-ankle vascular index (CAVI) and ankle-brachial index (ABI)) following glucose ingestion and aerobic exercise. Method: This semi-experimental research was conducted on 40 inactive women subjects in the age group of 20 to 45 years, Shahrood city. After 12 hours of fasting, FBS and MDA were measured. Then the measurements of weight, height, body composition and arterial stiffness (CAVI and ABI) were taken at baseline and response; 30 minutes, acute endurance activity with 65% maximum heart rate was performed on the treadmill. Consumption of 75 grams of glucose in 225 ml of water was done after 30 minutes of finishing the activity, and after that, another hour of inactive rest was done, and at the end, arterial stiffness and blood sugar were measured again. Results: There is a significant relationship between the baseline levels of MDA and FBS with the baseline levels of CAVI (p=0.001), but there was no significant relationship between these baseline levels of these two variables with changes in CAVI after exercise and glucose ingestion (p>0.05). ABI was also significantly related to baseline levels of MDA and FBS in both baseline (p=0.001) and response (p=0.003) levels. Conclusion: In general, it can be concluded that baseline arterial stiffness is related to baseline levels of MDA and FBS, but in the face of conditions disturbing homeostasis such as exercise and glucose ingestion, only the changes in peripheral arterial stiffness (ABI) are related to these cases.

کلیدواژه‌ها [English]

  • Arterial Stiffness
  • Blood Sugar
  • Malondialdehyde
  • Endurance Exercise

مراجع

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 11، شماره 1
فروردین 1403
صفحه 82-95

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سابقه مقاله

  • تاریخ دریافت: 12 خرداد 1402
  • تاریخ بازنگری: 07 مهر 1402
  • تاریخ پذیرش: 08 مهر 1402

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