تأثیر هشت هفته تمرین همزمان بر مقاومت انسولینی و مقادیر پلاسمایی رزیستین و گلوکز مردان میانسال دارای اضافه وزن و چاق

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 استادیار فیزیولوژی ورزشی. اداره تربیت بدنی دانشگاه فرهنگیان کرمان. کرمان. ایران.

2 استاد گروه فیزیولوژی ورزش، دانشکده علوم ورزشی، دانشگاه بیرجند، بیرجند، ایران.

3 کارشناسی ارشد فیزیولوژی ورزش، مسئول تربیت بدنی، اداره آموزش و پرورش دهدشت.

10.22049/jahssp.2022.27610.1429

چکیده

هدف: افراد دارای اضافه وزن و چاق که فعالیت بدنی ندارند، معمولا در معرض برخی بیماری­های متابولیکی و قلبی و عروقی مانند دیابت نوع 2 و گرفتگی عروق کرونری و پرفشار خونی قرار دارند. هدف از این تحقیق بررسی تأثیر هشت هفته تمرین همزمان (مقاومتی و استقامتی) بر مقاومت انسولینی و مقادیر پلاسمایی رزیستین و گلوکز مردان میانسال دارای اضافه وزن و چاق شهر یاسوج بود. روش شناسی: روش تحقیق از نوع نیمه تجربی با طرح پیش آزمون و پس آزمون بود. جامعه آماری مردان دارای اضافه وزن و چاق 30 تا 45 ساله شهر یاسوج بودند. روش نمونه گیری هدفمند بود و 30 نفر به عنوان نمونه آماری انتخاب و به صورت تصادفی ساده به 2 گروه تمرین همزمان و کنترل تقسیم شدند. آزمودنی­های گروه تجربی 8 هفته تمرین همزمان و هر هفته 3 جلسه را انجام دادند. داده­های مربوط به مقاومت انسولینی، رزیستین و گلوکز پلاسمایی در قبل و بعد از اجرای تمرینات همزمان با استفاده از آزمون­های کولموگروف اسمیرنوف، t  وابسته و مستقل در سطح معنی­داری 05/0>p تحلیل شدند. یافته‌ها: نتایج پژوهش نشان داد مقاومت انسولینی، سطوح رزیستین و گلوکز پلاسمایی در پس آزمون در گروه تجربی نسبت به گروه کنترل کاهش معناداری داشتند (05/0>p). در مقابل، در گروه کنترل در همه متغیرها تغییر معناداری مشاهده نشد (05/0> p). سطوح رزیستین و گلوکز پلاسمایی در پس آزمون گروه تجربی کاهش معنی دار داشتند ولی در گروه کنترل تفاوت معناداری مشاهده نشد (05/0>p). نتیجه‌گیری: بنابراین، می­توان اجرای 8 هفته تمرین همزمان مقاومتی و استقامتی که در یک جلسه اجرا می­شدند را به عنوان یکی از روش­های پیشگیرانه و غیردارویی برای بهبود وضعیت سلامت متابولیکی و قلبی و عروقی مردان میانسال دارای اضافه وزن و چاق پیشنهاد داد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

The effect of eight weeks of concurrent training on insulin resistance and resistin and glucose plasma levels in middle-aged overweight and obese men

نویسندگان [English]

  • Morad Hosseini 1
  • Mehdi Mogharnasi 2
  • Omid Zafarmand 3
1 Assistant Professor of Sports Physiology. Physical Education Department. Farhangian University of Kerman. Kerman. Iran.
2 Professor of Exersice Physiology, Faculty of Sports Sciences, University of Birjand, Birjand, Iran.
3 Master of Sports Physiology, In charge of physical education, Dehdasht Education Office.
چکیده [English]

Aim: Overweight and obese people who do not engage in physical activity or exercise are usually at risk for certain metabolic, cardiovascular, and type 2 diseases, such as type 2 diabetes, coronary artery disease, and hypertension. The aim of this study was to investigate the effect of eight weeks of concurrent training (resistance and endurance) on insulin resistance and plasma levels of resistin and glucose in overweight and obese middle-aged men in Yasuj. Methods: The research method was quasi-experimental with pre-test and post-test design.  The statistical population was overweight and obese men aged 30 to 45 years in Yasuj. The sampling method was purposeful and 30 people were selected as a statistical sample and were randomly divided into two groups of  concurrent training and control. The subjects in the experimental group performed 8 weeks of  concurrent training and 3 sessions per week. Data on insulin resistance,  plasma resistin and glucose before and after concurrent training were analyzed using Kolmogorov-Smirnov, dependent and independent t-tests at a significant level of p<0.05. Results: The results showed that insulin resistance, resistin and plasma glucose levels in the post-test in the experimental group were significantly reduced compared to the control group (p <0.05). In contrast, no significant change was observed in all variables in the control group (p > 0.05). Conclusions: Therefore, it is can to suggest 8 weeks of concurrent resistance and endurance training that were performed in one session as one of the preventive and non-pharmacological methods to improve the metabolic, cardiovascular health status of overweight and obese middle-aged men.

کلیدواژه‌ها [English]

  • Insulin esistance
  • Resistin
  • Glucose

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

1. KhajehLandi M, Bolboli L, Bolbol S, Zabihi B. Effect of One Course Pilates Exercise Program on Serum Levels of Resistin, Visfatin, and Chemerin in Overweight Women. The Horizon of Medical Sciences. 2020;27(1):93-113. [In Persian]
2.Ferrari F, Bock PM, Motta MT, Helal L. Biochemical and molecular mechanisms of glucose uptake stimulated by physical exercise in insulin resistance state: role of inflammation. Arquivos brasileiros de cardiologia. 2019;113:1139-48.
3.Gholamimoghadam S, Mogharnasi M. The Effect of Spirulina Supplementation and Circuit Resistance Training (CRT) on Plasma Values of Resistin, and Some Indicators of Body Composition of Overweight, and Obese Police Officers. Journal of Police Medicine. 2021;10(3):149-58. [In Persian]
4.Baigzadeh M, Hossienpour Delavar S, Safikhani H. The Effect of Training (Aerobic and concurrent) and Cinnamon Supplementation on the Plasma Levels of Visfatin and Adiponectin in Overweight Diabetic Men. Journal of Clinical Research in Paramedical Sciences. 2020;9(2). [In Persian]
5.Tan Y, Tam CC, Rolston M, Alves P, Chen L, Meng S, et al. Quercetin ameliorates insulin resistance and restores gut microbiome in mice on high-fat diets. Antioxidants. 2021;10(8):1251.
6.Kojta I, Chacińska M, Błachnio-Zabielska A. Obesity, bioactive lipids, and adipose tissue inflammation in insulin resistance. Nutrients. 2020;12(5):1305.
7.Liu S-X, Zheng F, Xie K-L, Xie M-R, Jiang L-J, Cai Y. Exercise reduces insulin resistance in type 2 diabetes mellitus via mediating the lncRNA MALAT1/microRNA-382-3p/resistin axis. Molecular Therapy-Nucleic Acids. 2019;18:34-44.
8.Ghalandari K, Shabani M, Khajehlandi A, Mohammadi A. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes. Archives of Physiology and Biochemistry. 2020:1-6. [In Persian]
9.Gutierrez AD, Flores CA, Naik S, Lee M, Asgarisabet P, Resman M, et al. Resistin levels decrease as insulin resistance increases in a Mexican-American cohort. Cytokine. 2021;148:155687.
10.TaheriChadorneshin H, Cheragh-Birjandi S, Goodarzy S, Ahmadabadi F. The impact of high intensity interval training on serum chemerin, tumor necrosis factor-alpha and insulin resistance in overweight women. Obesity medicine. 2019;14:100101. [In Persian]
11.Wolfe BE, Jimerson DC, Orlova C, Mantzoros CS. Effect of dieting on plasma leptin, soluble leptin receptor, adiponectin and resistin levels in healthy volunteers. Clinical endocrinology. 2004;61(3):332-8.
12.Marcell TJ, McAuley KA, Traustadóttir T, Reaven PD. Exercise training is not associated with improved levels of C-reactive protein or adiponectin. Metabolism. 2005;54(4):533-41.
13.Perseghin G, Burska A, Lattuada G, Alberti G, Costantino F, Ragogna F, et al. Increased serum resistin in elite endurance athletes with high insulin sensitivity. Diabetologia. 2006;49(8):1893-900.
14.Abella V, Scotece M, Conde J, López V, Lazzaro V, Pino J, et al. Adipokines, metabolic syndrome and rheumatic diseases. Journal of immunology research. 2014;2014.
15.Karimi N, Roshan VD, Bayatiyani ZF. Individually and combined water-based exercise with ginger supplement, on systemic inflammation and metabolic syndrome indices, among the obese women with breast neoplasms. Iranian journal of cancer prevention. 2015;8(6). [In Persian]
16.Shahgholi Abasi R, Izadi M, Soheili S, Imanzadeh R. Serum resistin and insulin resistance responses to long-term physical exercise in the absence of diet control in middle-aged obese men. Journal of Mazandaran University of Medical Sciences. 2012;21(86):126-30. [In Persian]
17.Kadoglou NP, Perrea D, Iliadis F, Angelopoulou N, Liapis C, Alevizos M. Exercise reduces resistin and inflammatory cytokines in patients with type 2 diabetes. Diabetes care. 2007;30(3):719-21.
18.Gray SR, Baker G, Wright A, Fitzsimons CF, Mutrie N, Nimmo MA, et al. The effect of a 12 week walking intervention on markers of insulin resistance and systemic inflammation. Preventive Medicine. 2009;48(1):39-44.
19.Uslu S, Kebapçı N, Kara M, Bal C. Relationship between adipocytokines and cardiovascular risk factors in patients with type 2 diabetes mellitus. Experimental and therapeutic medicine. 2012;4(1):113-20.
20.Monzillo LU, Hamdy O, Horton ES, Ledbury S, Mullooly C, Jarema C, et al. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obesity research. 2003;11(9):1048-54.
21.Osawa H, Tabara Y, Kawamoto R, Ohashi J, Ochi M, Onuma H, et al. Plasma resistin, associated with single nucleotide polymorphism− 420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population. Diabetes care. 2007;30(6):1501-6.
22.Fealy CE, Nieuwoudt S, Foucher JA, Scelsi AR, Malin SK, Pagadala M, et al. Functional high‐intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2 diabetes. Experimental physiology. 2018;103(7):985-94.
23.Jung SH, Park HS, Kim K-S, Choi WH, Ahn CW, Kim BT, et al. Effect of weight loss on some serum cytokines in human obesity: increase in IL-10 after weight loss. The Journal of nutritional biochemistry. 2008;19(6):371-5.
24.Suh S, Jeong I-K, Kim MY, Kim YS, Shin S, Kim SS, et al. Effects of resistance training and aerobic exercise on insulin sensitivity in overweight korean adolescents: a controlled randomized trial. Diabetes & metabolism journal. 2011;35(4):418-26.
25.Suntraluck S, Tanaka H, Suksom D. The relative efficacy of land-based and water-based exercise training on macro-and microvascular functions in older patients with type 2 diabetes. Journal of aging and physical activity. 2017;25(3):446-52.
26. Dadashzadeh, A., Poozesh Jadidi, R. Effect of HIIT and curcumin consumption on serum troponin I and creatine kinase levels in isopretrenol-treated male mice. Journal of Applied Health Studies in Sport Physiology, 2021; 8(1): 44-53. [In Persian]
27.Riyahi Malayeri S, Saei M. Changes in Insulin resistance and serum levels of resistin after 10 weeks high intensity interval training in overweight and obese men. Sport Physiology & Management Investigations. 2019;10(4):31-42. [In Persian]