تأثیر هشت هفته تمرین مقاومتی به همراه مکمل عصاره چای سبز بر سطوح سرمی آدیپونکتین و پنتراکسین-3 در مردان چاق

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 گروه تربیت بدنی و علوم ورزشی، دانشکده علوم انسانی و اجتماعی، دانشگاه کردستان

2 گروه فیزیولوژی ورزشی، دانشکده علوم انسانی و اجتماعی، دانشگاه کردستان، سنندج، ایران

10.22049/jahssp.2022.27526.1411

چکیده

هدف: چاقی و اختلالات متابولیکی از عوامل خطرساز سلامتی هستند و فعالیت بدنی و مکمل‌های گیاهی نقش مهمی در کنترل وزن دارند. بنابراین، پژوهش حاضر با هدف بررسی تاثیر هشت هفته تمرین مقاومتی به همراه مکمل عصاره چای سبز بر سطوح سرمی آدیپونکتین و پنتراکسین-3 در مردان چاق انجام گرفت. روش شناسی: در یک کار­آزمایی تجربی- با طرح دو سوکور تعداد 30 مرد سالم با دامنه سنی 38-26 سال و شاخص توده بدنی بیشتر از 30 کیلوگرم بر متر مربع به طور تصادفی در سه گروه 10 نفره شامل گروه مکمل عصاره چای سبز، گروه تمرین+ مکمل عصاره چای سبز و گروه تمرین+ دارونما قرار گرفتند. گروه‌های تمرین، هشت هفته تمرین مقاومتی را سه جلسه در هفته انجام دادند. همه گروه‌ها به مدت هشت هفته روزانه 600 میلی­گرم مکمل عصاره چای سبز یا دارونما را در دو وعده 300 میلی­گرمی دریافت کردند. قبل و بعد از برنامه تمرین شاخص‌های آنتروپومتریکی و سطح سرمی آدیپونکتین و پنتراکسین-3 اندازه‌گیری شد. تجزیه و تحلیل داده­ها با استفاده از آزمون تحلیل واریانس با اندازه‌گیری مکرر به صورت طرح 2×3 در سطح معنی­داری 05/0≥p انجام شد. یافته‌ها: تمرین مقاومتی به همراه مکمل عصاره چای سبز موجب کاهش معنی­دار وزن بدن (02/0=p)، شاخص توده بدنی (02/0=p) و نسبت دور کمر به دور لگن (04/0=p) در گروه تمرین به همراه مکمل عصاره چای سبز می­شود، اما تغییر معنی­داری در سطوح سرمی آدیپونکتین (06/0=p) و پنتراکسین-3 (27/0=p) مشاهده نشد.  نتیجه‌گیری: به نظر می‌رسد که مصرف چای سبز همراه با تمرین مقاومتی می‌تواند در کنترل وزن مردان چاق مفید باشد، اما در مورد تاثیر این دو بر آدیپونکتین و پنتراکسین-3، هنوز امکان نتیجه گیری قطعی وجود ندارد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of Eight Weeks of Resistance Training with Green Tea Extract Supplement On Serum Levels of Adiponectin and Pentraxin-3 In Obese Men

نویسندگان [English]

  • Mehran Shamsi 1
  • Mohammad Rahman Rahimi 2
1 Department of Physical Education and Sports Sciences, Faculty of Humanities and Social Sciences, University of Kurdistan
2 ِDepartment of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
چکیده [English]

Aim: Obesity and metabolic disorders are considered as risk factors for health and both physical activity and herbal supplements have appreciable effects on weight control. Therefore, The aim of present study was to investigate the effect of eight weeks of resistance training with green tea extract supplementation on serum levels of adiponectin and pentraxin-3 in obese men. Methods: In an experimental experiment - with a double-blind design, 30 healthy men with an age range of 26-38 years and a body mass index of more than 30 kg / m2 were randomly divided into three groups of 10, including the green tea extract supplement group, exercise group + Green tea extract supplement and exercise group + placebo were included. The experimental subjects received circuit resistance training, which was performed three times a week. All groups were given 600 mg green tea extract supplements or placebo for eight weeks in two doses of 300 mg daily. Anthropometric indices, and blood sampling were measured before and after eight weeks of circuit resistance training. Data analysis was performed using analysis of variance with cunning measurement as a 3.2 design at a significance level of p≥0.05. Results: The results showed that 8 weeks of resistance training with green tea extract supplement significantly reduced body weight (p≥0.02), body mass index (p≥0.02) and waist to hip ratio (p≥0.04) in the training group with green tea extract supplement, but a significant change in levels. Serum adiponectin (p=0.06) and pentraxin-3 (p=0.27) were not observed. Conclusions: It seems that consumption of green tea extract along with resistance training could be beneficial in obese males’ weight control, however; no firm conclusions can still be drawn on their concomitance.

کلیدواژه‌ها [English]

  • resistance training
  • green tea extract
  • adiponectin
  • pentraxin-3

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

مراجع

  1.  

    1. Kraemer WJ, Ratamess NA, French DN. Resistance training for health and performance. Current sports medicine reports. 2002;1(3):165-71.
    2. Medicine ACoS. Progression models in resistance training for healthy adults. Med Sci Spor Exerc. 2002;34:364-80.
    3. Fleck SJ, Kraemer W. Designing resistance training programs, 4E: Human Kinetics; 2014.
    4. Eriksson J, Taimela S, Koivisto V. Exercise and the metabolic syndrome. Diabetologia. 1997;40(2):125-35.
    5. Tofighi A, ghaffari Y, afsarbegi N. The effects of a selected aerobic exercise along with a controlled diet on weight loss in obese men. Iranian Journal of Nutrition Sciences & Food Technology. 2014;9(2):85-94.
    6. Bouchard C, Jean D. Physical activity and health: hypertensive, metabolic, and atheroschorotic diseases. Research Quarterly for Exercise and Sport. 1995;66:268-75.
    7. Nammi S, Koka S, Chinnala KM, Boini KM. Obesity: an overview on its current perspectives and treatment options. Nutrition Journal. 2004;3(1):3.
    8. Abedi B, Poorfahkimi Abarghu J, Ghadami A, Amini Rarani S. The Effects of Resistance Training and Green Tea Supplementation on Lipid Profile and Insulin Resistance in Obese and Overweight Men. complementary Medicine Journal. 2017;7(1):1767-76.
    9. Rahmani-Nia F, Rahnama N, Hojjati Z, Soltani B. Acute effects of aerobic and resistance exercises on serum leptin and risk factors for coronary heart disease in obese females. Sport Sciences for Health. 2008;2(3):118-24.
    10. Jankun J, Selman SH, Swiercz R, Skrzypczak-Jankun E. Why drinking green tea could prevent cancer. Nature. 1997;387(6633):561-.
    11. Mohammadi S, Hasseinzadeh Attar M, Karimi M, Hossainnezhad A, Eshraghian M, Hosseini S, et al. The Effects of Green Tea Extract on Serum Adiponectin Concentration and Insulin Resistance in Patients with Type 2 Diabetes Mellitus. Journal of Zanjan University of Medical Sciences. 2010;18(70):44-57.
    12. Trujillo ME, Scherer PE. Adipose tissue-derived factors: impact on health and disease. Endocrine reviews. 2006;27(7):762-78.
    13. Guzik TJ, Mangalat D, Korbut R. Adipocytokines - novel link between inflammation and vascular function? J Physiol Pharmacol. 2006;57(4):505-28.
    14. Ronti T, Lupattelli G, Mannarino E. The endocrine function of adipose tissue: an update. Clin Endocrinol (Oxf). 2006;64(4):355-65.
    15. Achari AE, Jain SK. Adiponectin, a therapeutic target for obesity, diabetes, and endothelial dysfunction. International journal of molecular sciences. 2017;18(6):1321.
    16. Yokoyama H, Emoto M, Araki T, Fujiwara S, Motoyama K, Morioka T, et al. Effect of aerobic exercise on plasma adiponectin levels and insulin resistance in type 2 diabetes. Diabetes care. 2004;27(7):1756-8.
    17. Okamoto Y, Kihara S, Funahashi T, Matsuzawa Y, Libby P. Adiponectin: a key adipocytokine in metabolic syndrome. Clinical science. 2006;110(3):267-78.
    18. Ibanez J, Izquierdo M. Resistance training improves cardiovascular risk factors in obese women despite a significative decrease in sensitivity and adiponectinemia in healthy men. 2003.
    19. Kraemer RR, Castracane VD. Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin. Experimental biology and medicine. 2007;232(2):184-94.
    20. Watson RR, Zibadi S, Preedy VR. Dietary components and immune function: Springer Science & Business Media; 2010.
    21. Fantuzzi G. Adipose tissue, adipokines, and inflammation. Journal of Allergy and Clinical Immunology. 2005;115(5):911-9.
    22. Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Molecular and cellular endocrinology. 2010;316(2):129-39.
    23. Slusher AL, Shibata Y, Whitehurst M, Maharaj A, Quiles JM, Huang C-J. Exercise reduced pentraxin 3 levels produced by endotoxin-stimulated human peripheral blood mononuclear cells in obese individuals. Experimental Biology and Medicine. 2017;242(12):1279-86.
    24. Norata GD, Marchesi P, Venu VKP, Pasqualini F, Anselmo A, Moalli F, et al. Deficiency of the long pentraxin PTX3 promotes vascular inflammation and atherosclerosis. Circulation. 2009;120(8):699-708.
    25. Miyaki A, Maeda S, Yoshizawa M, Misono M, Sasai H, Shimojo N, et al. Is pentraxin 3 involved in obesity-induced decrease in arterial distensibility? Journal of atherosclerosis and thrombosis. 2010;17(3):278-84.
    26. Osorio-Conles O, Guitart M, Chacón M, Maymo-Masip E, Moreno-Navarrete J, Montori-Grau M, et al. Plasma PTX3 protein levels inversely correlate with insulin secretion and obesity, whereas visceral adipose tissue PTX3 gene expression is increased in obesity. American Journal of Physiology-Endocrinology and Metabolism. 2011;301(6):E1254-E61.
    27. Oliveira Ed, Gotschlich C, Liu T. Primary structure of human C-reactive protein. Journal of Biological Chemistry. 1979;254(2):489-502.
    28. Salio M, Chimenti S, De Angelis N, Molla F, Maina V, Nebuloni M, et al. Cardioprotective function of the long pentraxin PTX3 in acute myocardial infarction. Circulation. 2008;117(8):1055-64.
    29. Mahmoudi A, Siauhkouhian M, Iranparvar M, Anari H, Seifi F. Plasma Changes of Chemerin and Pentraxin-3 Following Eight Weeks of Endurance Exercise in Men with Non-Alcoholic Fatty Liver Disease. Journal of Ardabil University of Medical Sciences. 2018;17(4):476-86.
    30. Zempo-Miyaki A, Fujie S, Sato K, Hasegawa N, Sanada K, Maeda S, et al. Elevated pentraxin 3 level at the early stage of exercise training is associated with reduction of arterial stiffness in middle-aged and older adults. Journal of human hypertension. 2016;30(9):521.
    31. Azali Alamdari K, khalafi m, Ghorbanian B. Effect of Aerobic Training on Serum Adiponectin and Ctrp-3 in Males with Metabolic Syndrome %J Iranian Journal of Endocrinology and Metabolism. 2017;18(5):368-77.
    32. Azali Alamdari K, Khalafi M. The Effect of Aerobic Exercise on Serum Levels of Adiponectin and CRP and Insulin Resistance in Women with Metabolic Syndrome %J Sport Physiology & Management Investigations. 2019;11(4):53-63.
    33. Azali Alamdari k, Khodaei O. The effect of high intensity interval training on serum adiponectin, insulin resistance and markers of metabolic syndrome in men with metabolic syndrome %J Journal of Applied Health Studies in Sport Physiology. 2018;5(1):69-76.
    34. Jahandideh AA, Rohani H, Rajabi H, Shariatzade Joneidi M. Effect of 8-weeks Combined Training on Leptin and Adiponectin levels in Obese Boys %J Journal of Applied Health Studies in Sport Physiology. 2021;8(2):31-40.
    35. Foroutan Y, Parnow AH, Daneshyar S. Independent and combined effects of intense aerobic training and detraining on serum levels of leptin, adiponectin and factors associated with overweight %J Journal of Applied Health Studies in Sport Physiology. 2017;4(2):34-41.
    36. Atashak S, Jafari A, Azarbayjani MA. The Influences of long-term resistance training on Adiponectin and lipid profiles levels in obese men. Razi Journal of Medical Sciences. 2011;18(86):1-11.
    37. Klimcakova E, Polak J, Moro C, Hejnova J, Majercik M, Viguerie N, et al. Dynamic strength training improves insulin sensitivity without altering plasma levels and gene expression of adipokines in subcutaneous adipose tissue in obese men. The Journal of Clinical Endocrinology & Metabolism. 2006;91(12):5107-12.
    38. Sone T, Kuriyama S, Nakaya N, Hozawa A, Shimazu T, Nomura K, et al. Randomized controlled trial for an effect of catechin-enriched green tea consumption on adiponectin and cardiovascular disease risk factors. Food & nutrition research. 2011;55(1):8326.
    39. Rashidi E, Hosseini Kakhak SAR, Askari R. The Effect of 8 Weeks Resistance Training With Low Load and High Load on Testosterone, Insulin-like Growth Factor-1, Insulin-like Growth Factor Binding Protein-3 Levels, and Functional Adaptations in Older Women. Salmand: Iranian Journal of Ageing. 2019;14(3):356-67.
    40. Bettuzzi S, Brausi M, Rizzi F, Castagnetti G, Peracchia G, Corti A. Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer research. 2006;66(2):1234-40.
    41. Hamidnejad Z, Avandi SM, Haghshenas R, Pakdel A. Effect of Five Weeks Circuit Resistance Training with Garlic Supplementation on Serum Levels of Adiponectin in Over Weight Female. Journal of Medicinal Plants. 2017;16(64):45-57.
    42. Mohamadzadeh salamat K. THE EFFECT OF CONTINUES AND PROGRESSIVE RESISTANCE TRAINING ON SERUM ADIPONECTIN AND VASPIN CONCENTRATION AND INSULIN RESISTANCE IN OVERWEIGHT MEN. Iranian Journal of Diabetes and Lipid Disorders. 2018;17(6):317-24.
    43. Park KM, Park SC, Kang S. Effects of resistance exercise on adipokine factors and body composition in pre-and postmenopausal women. Journal of exercise rehabilitation. 2019;15(5):676.
    44. Fatouros I, Tournis S, Leontsini D, Jamurtas A, Sxina M, Thomakos P, et al. Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related. The Journal of Clinical Endocrinology & Metabolism. 2005;90(11):5970-7.
    45. Ahmadizad S, Haghighi AH, Hamedinia MR. Effects of resistance versus endurance training on serum adiponectin and insulin resistance index. European journal of Endocrinology. 2007;157(5):625-31.
    46. Jürimäe J, Purge P, Jürimäe T. Adiponectin is altered after maximal exercise in highly trained male rowers. European journal of applied physiology. 2005;93(4):502-5.
    47. Mazzali G, Di Francesco V, Zoico E, Fantin F, Zamboni G, Benati C, et al. Interrelations between fat distribution, muscle lipid content, adipocytokines, and insulin resistance: effect of moderate weight loss in older women. The American journal of clinical nutrition. 2006;84(5):1193-9.
    48. ABEDI B, AZARBAYJANI MA, PEERI M, RASAEE MJ. The effect of a single session of resistance training on serum adiponectin level and insulin resistance index in sedentary men. Arak Medical University Journal. 2011;14(5):53-620.
    49. Kriketos AD, Gan SK, Poynten AM, Furler SM, Chisholm DJ, Campbell LV. Exercise increases adiponectin levels and insulin sensitivity in humans. Diabetes care. 2004;27(2):629-30.
    50. Olson T, Dengel D, Leon A, Schmitz K. Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women. International journal of obesity. 2007;31(6):996.
    51. Hara T, Fujiwara H, Nakao H, Mimura T, Yoshikawa T, Fujimoto S. Body composition is related to increase in plasma adiponectin levels rather than training in young obese men. European journal of applied physiology. 2005;94(5-6):520-6.
    52. Krakoff J, Funahashi T, Stehouwer CD, Schalkwijk CG, Tanaka S, Matsuzawa Y, et al. Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian. Diabetes care. 2003;26(6):1745-51.
    53. Matsubara M, Maruoka S, Katayose S. Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women. European journal of endocrinology. 2002;147(2):173-80.
    54. Esposito K, Pontillo A, Di Palo C, Giugliano G, Masella M, Marfella R, et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. Jama. 2003;289(14):1799-804.
    55. Monzillo LU, Hamdy O, Horton ES, Ledbury S, Mullooly C, Jarema C, et al. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obesity. 2003;11(9):1048-54.
    56. Abdel-lateif DM, El-Shaer SS. Association between changes in serum vaspin concentrations and changes of anthropometric and metabolic variables in obese subjects after weight reduction. Journal of American Science. 2012;8(4):261-77.
    57. Lau DC, Douketis JD, Morrison KM, Hramiak IM, Sharma AM, Ur E. 2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children [summary]. Cmaj. 2007;176(8):S1-S13.
    58. Yang W-S, Lee W-J, Funahashi T, Tanaka S, Matsuzawa Y, Chao C-L, et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. The Journal of Clinical Endocrinology & Metabolism. 2001;86(8):3815-9.
    59. Chu SH, Park J-H, Lee MK, Jekal Y, Ahn KY, Chung JY, et al. The association between pentraxin 3 and insulin resistance in obese children at baseline and after physical activity intervention. Clinica Chimica Acta. 2012;413(19-20):1430-7.
    60. Slusher AL, Mock JT, Whitehurst M, Maharaj A, Huang C-J. The impact of obesity on pentraxin 3 and inflammatory milieu to acute aerobic exercise. Metabolism-Clinical and Experimental. 2015;64(2):323-9.
    61. Miyaki A, Maeda S, Choi Y, Akazawa N, Tanabe Y, Ajisaka R. Habitual aerobic exercise increases plasma pentraxin 3 levels in middle-aged and elderly women. Applied physiology, nutrition, and metabolism. 2012;37(5):907-11.

     

مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 8، شماره 2
مهر 1400
صفحه 94-101

فایل ها

سابقه مقاله

  • تاریخ دریافت: 03 آذر 1400
  • تاریخ بازنگری: 13 دی 1400
  • تاریخ پذیرش: 13 دی 1400

هم رسانی

ارجاع به این مقاله

آمار