پاسخ فاکتورهای انعقادی و فیبرینولیز به یک جلسه تمرین مقاومتی در مردان ورزشکار و غیرورزشکار

نوع مقاله : مقاله پژوهشی Released under CC BY 4.0 license I Open Access I

نویسندگان

1 کارشناسی ارشد فیزیولوژی ورزشی کاربردی، گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه زنجان، زنجان ، ایران

2 دانشیار، گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه زنجان، زنجان ، ایران .

3 استادیار، گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه زنجان، زنجان ، ایران

10.22049/jahssp.2021.27347.1376

چکیده

هدف: هدف این پژوهش، بررسی اثر تمرین مقاومتی یک جلسه­ای بر سطح انعقاد و عملکرد سیستم فیبرینولیتیک مردان ورزشکار و غیرورزشکار بود. روش شناسی: تحقیق حاضر از نوع نیمه تجربی بود. 18 مرد ورزشکار و غیرورزشکار (9 ورزشکار و 9 غیر ورزشکار) با میانگین سنی 20 تا 30 سال به روش نمونه گیری در دسترس انتخاب شدند. بعد از صرف صبحانه استاندارد، اولین مرحله خونگیری (5 میلی­لیتر) در حالت نشسته انجام شد. سپس آزمودنی ها  تمرین مقاومتی دایره ای را در 10 ایستگاه با 60٪ تکرار بیشینه (هر ایستگاه شامل 12 تکرار ، 30 ثانیه فعالیت و 30 ثانیه استراحت) و 3 دقیقه استراحت بین هر دور را انجام دادند. یک ساعت پس از پایان پروتکل تمرین ، خونگیری مرحله دوم دقیقاً همانند مرحله اول انجام شد. زمان نسبی ترومبوپلاستین  و زمان پروترومبین پلاسما با روش انعقاد اندازه گیری شد. برای اندازه گیری D-dimer از دستگاه mini-Vidas استفاده شد. تجزیه و تحلیل داده ها با استفاده از آزمون T مستقل ، T زوجی و کوواریانس انجام شد.یافته­ها: بر طبق نتایج تمرین مقاومتی یک جلسه ای بر زمان پروترومبین ، زمان نسبی ترومبوپلاستین و سطح D-dimer پلاسما مردان ورزشکار و غیر ورزشکار تأثیری ندارد (05/ 0P>). پروترومبین و زمان نسبی ترومبوپلاستین و سطح D-dimer پلاسما گروه غیر ورزشکار تغییر قابل توجهی نداشت  (05/ 0P>). با این حال ، تجزیه و تحلیل درون گروهی نشان داد پس از یک جلسه تمرین مقاومتی در گروه ورزشکار، زمان پروترومبین و زمان ترومبوپلاستین پلاسما کاهش قابل توجهی دارد(05/0p <).  نتیجه گیری: با توجه به عدم تأثیر تمرین مقاومتی یک جلسه ای بر زمان پروترومبین ، زمان نسبی ترومبوپلاستین و سطح D-dimer در مردان ورزشکار و غیر ورزشکار، احتمالاً بتوان گفت که تمرینات مقاومتی دایره ای در مردان ورزشکاران و غیر ورزشکاران بی خطر بوده و هیچ تاثیری بر مارکرهای انعقادی و فیبرینولیز ندارد.

کلیدواژه‌ها


عنوان مقاله [English]

Response of coagulation factors and fibrinolysis to a resistance training session in male athletes and non-athletes

نویسندگان [English]

  • Mehrnaz Zolfeghari Narestan 1
  • Agha Ali Ghasemnian 2
  • Hasan Ghareh Khani 3
1 Master student in sport physiology, Zanjan university, Zanjan, Iran
2 Associate Professor, Department of Sport Sciences, Faculty of Humanities, University of Zanjan, Zanjan, Iran
3 Assistant Professor,Department of Sport Sciences, Faculty of Humanities, University of Zanjan, Zanjan, Iran
چکیده [English]

Aim:  The purpose of this study  was to investigate the response of coagulation and fibrinolysis factors to a circuit resistance training session in male athletes and non-athletes.
Methods: This research was a semi-experimental study. 18 male athletes and non-athletes (9 athletes and 9 non-athletes) with 20 to 30 years old average age were selected by the available sampling method. After consuming a standard breakfast, the first stage of blood collection (5 ml ) was performed in the Sitting Position. Then Subjects performed a circular resistance training at 10 stations with 60% of a maximum repetition (each station consists of 12 repetitions, 30 seconds activity, and 30 seconds rest) and 3 minutes of rest between each set. Then, one hour after the end of the training protocol, the second blood sampling was performed exactly as same as the first stage. Prothrombin time and relative plasma thromboplastin time were measured by Coagulation Method. A mini-Vidas device was used to measure of D-dimer. Data were analyzed using independent-sample- T-test, paired- sample-T test, and Covariance. 
 Results: Results showed that one session resistance training did not affect plasma prothrombin time, relative plasma thromboplastin time, and plasma D-dimer level of male athletes and non-athletes (P>0.05). Also, in-group changes in Prothrombin and relative thromboplastin time and plasma D-dimer level in the non-athlete group did not change significantly (P>0.05). However, the in-group analysis showed that after one session of resistance training in the athlete group, prothrombin time and plasma thromboplastin time was significantly decreased (p < 0.05).
 Conclusion: Regarding lack of effect one session resistance training on plasma prothrombin time, relative thromboplastin time and 
D-dimer level in male athletes and non-athletes, it can probably be said that circular strength training is safe in athletes and non-athletes. also, it does not affect coagulation markers and fibrinolysis.

کلیدواژه‌ها [English]

  • Prothrombin (PT)
  • Thromboplastin (PTT)
  • D-dimer
  • resistance training
1.          Nazar Ali P., Hosseini AS, Hojjati P., Jafari M. The effect of RAST anaerobic test on the main markers of blood coagulation system in active and inactive healthy young women. Applied research in sports health and performance. 2013; 2(1). 49-58.
2.          Azimpour M, Shahdadi A. Response of coagulation indices to two types of exercise of eccentric and isometric in male bodybuilding athletes. Qom University of Medical Sciences Journal. 2016;10(2):13-21.
3.          Bick RL. Disorders of thrombosis and hemostasis: clinical and laboratory practice: Lippincott Williams & Wilkins; 2002.
4.          Gelfer Y, Tavor H, Oron A, Peer A, Halperin N, Robinson D. Deep vein thrombosis prevention in joint arthroplasties: continuous enhanced circulation therapy vs low molecular weight heparin. The Journal of arthroplasty. 2006;21(2):206-14.
5.          El-Sayed MS, Ali ZE-S, Ahmadizad S. Exercise and training effects on blood haemostasis in health and disease. Sports medicine. 2004;34(3):181-200.
6.          El-Sayed MS, Ali N, Ali ZE-S. Aggregation and activation of blood platelets in exercise and training. Sports medicine. 2005;35(1):11-22.
7.          Guyton A, Hall J. Textbook of medical physiology, 11th. Elsevier Inc.; 2006.
8.          Dikshit S. Fibrinogen Degradation Products and Periodontitis: Deciphering the Connection. Journal of Clinical and Diagnostic Research: Jcdr. 2015;9(12):ZC10.
9.          Patil HR, O’Keefe JH, Lavie CJ, Magalski A, Vogel RA, McCullough PA. Cardiovascular damage resulting from chronic excessive endurance exercise. Missouri medicine. 2012;109(4):312.
10.        deJong AT, Womack CJ, Perrine JA, Franklin BA. Hemostatic responses to resistance training in patients with coronary artery disease. Journal of Cardiopulmonary Rehabilitation and Prevention. 2006;26(2):80-3.
11.        Daiber A, Steven S, Weber A, Shuvaev VV, Muzykantov VR, Laher I, et al. Review for Themed Issue ‘Redox biology and oxidative stress in health and.
12.        Shad R, Bijeh N, Fathi M. Response of Lipoprotein a, Blood Coagulation and Fibrinolysis Factors to Aerobic Exercise in Overweight Women. Journal of Payavard Salamat. 2019;12(6):447-57.
13.        Hoseinzadeh M, Dabidi Roshan V, Ghanbari A. The effect of physical activity and sauna bathing on some of the Cardiovascular parameters of healthy young men. Metabolism and Exercise. 2011;1(2):141-53.
14.        Kupchak BR, Creighton BC, Aristizabal JC, Dunn-Lewis C, Volk BM, Ballard KD, et al. Beneficial effects of habitual resistance exercise training on coagulation and fibrinolytic responses. Thrombosis research. 2013;131(6):e227-e34.
15.        Nagelkirk P, Scalzo R, Harber M, Kaminsky L. The influence of acute resistance training and body composition on coagulation and fibrinolytic activity in low-risk women. International journal of sports medicine. 2010;31(07):458-62.
16.        Kahraman S, Demirkan F, Bediz C, Alacacioglu I, Aksu I. The effect of exercise on fibrinolytic and coagulation systems in healthy volunteers. J of Thromb Haemost. 2007;2:362-8.
17.        Ghanbari Niaki A , Tayebi SM , Ghorbanalizadeh Ghaziani F ,Hakimi   J ,The effect of a single-circuit weight-training session on lipid profiles and serum lipoprotein changes in students of physical education. Journal of Applied Exercise Physiology 2006;2(4):35-44.
18.        Satarifard S, Gaeini AA, Choobineh S. The Effect of Exercise on the Serum Interleukin-17, Interferon-γ and CRP of the Endurance Athletes in Cold and Normal Temperature Condition. Medical Journal of Tabriz University of Medical Sciences & Health Services. 2012;34(4):93-86.
19.        Satarifard S, Gaeini AA, Choobineh S. The Effect of Exercise on the Serum Interleukin-17, Interferon-γ and CRP of the Endurance Athletes in Cold and Normal Temperature Condition. Medical Journal of Tabriz University of Medical Sciences & Health Services. 2012;34(4).
20.        Asouri M. Acute Effects of Jujube Ziziphus Solution Feeding before a Single Session of Circuit Resistance Exercise on Apoptosis of Human Neutrophil. Journal of Applied Exercise Physiology. 2017;13(25):97-114.
21.        Shamsoddini A, Sobhani V, Chehreh MEG, Alavian SM, Zaree A. Effect of aerobic and resistance exercise training on liver enzymes and hepatic fat in Iranian men with nonalcoholic fatty liver disease. Hepatitis monthly. 2015;15(10).
22.        Mirsaeidi B, B N, M S. The effect of 8 weeks of combined training (aerobic-resistance) on blood coagulation, fibrinolytic factors in elderly men. nursing of the vulnerable journal. 2016;3(7):1-11.
23.        amini a, Kordi MR, Gaini AA, Ahmadi A, Veysi K. Effect of resistance exercise on coagulation and fibrinolytic factors in inactive aged men. Quarterly of Horizon of Medical Sciences. 2012;18(3):103-8.
24.        Tofighi A, Karimnia Saheb V. The Effect of An Acute High Intensity Resistance Exercise on Blood Coagulation and Fibrinolysis Factors Pre-and Post 10 Weeks Resistance Training in Obese Children. Sport Physiology. 2017;9(35):147-64.
25.        Menzel K, Hilberg T. Coagulation and fibrinolysis are in balance after moderate exercise in middle-aged participants. Clinical and Applied Thrombosis/Hemostasis. 2009;15(3):348-55.
26.        Menzel K, Hilberg T. Blood coagulation and fibrinolysis in healthy, untrained subjects: effects of different exercise intensities controlled by individual anaerobic threshold. European journal of applied physiology. 2011;111(2):253-60.
27.        Connes P, Tripette J, Chalabi T, Beltan E, Etienne-Julan M, Chout R, et al. Effects of strenuous exercise on blood coagulation activity in sickle cell trait carriers. Clinical hemorheology and microcirculation. 2008;38(1):13-21.
28.        Ribeiro J, Almeida-Dias A, Oliveira A, Mota J, Appell H-J, Duarte J. Exhaustive exercise with high eccentric components induces prothrombotic and hypofibrinolytic responses in boys. International journal of sports medicine. 2007;28(03):193-6.
29.        Cohen R, Epstein S, Cohen L, Dennis L. Alterations of fibrinolysis and blood coagulation induced by exercise, and the role of beta-adrenergic-receptor stimulation. The Lancet. 1968;292(7581):1264-6.
30.        Peat E, Dawson M, McKenzie A, Hillis WS. The effects of acute dynamic exercise on haemostasis in first class Scottish football referees. British journal of sports medicine. 2010;44(8):573-8.
31.        Amini A, Kordi MR, Gaini AA, Ahmadi A, Ayoubian H, Lahoorpour F. The effects of aerobic exercises on coagulation and fibrinolytic factors in inactive aged men. Scientific Journal of Kurdistan University of Medical Sciences. 2011;15(4):25-32.
32.        Posthuma JJ, van der Meijden PE, Ten Cate H, Spronk HM. Short-and Long-term exercise induced alterations in haemostasis: a review of the literature. Blood reviews. 2015;29(3):171-8.
33.        Lund T, Kvernmo H, Osterud B. Cellular activation in response to physical exercise: the effect of platelets and granulocytes on monocyte reactivity. Blood coagulation & fibrinolysis: an international journal in haemostasis and thrombosis. 1998;9(1):63-9.
34.        Boldt L-H, Fraszl W, Röcker L, Schefold JC, Steinach M, Noack T, et al. Changes in the haemostatic system after thermoneutral and hyperthermic water immersion. European journal of applied physiology. 2008;102(5):547-54.
35.        Ghanbari A, Tayebi S, Delrouz H. The effect of a single session eccentric resistance exercise on some blood coagulation factors of inactive male students. Scientific Journal of Iranian Blood Transfusion Organization. 2011;8(3).
36.        Van den Burg P, Hospers J, Van Vliet M, Mosterd W, Huisveld I. Unbalanced haemostatic changes following strenuous physical exercise: a study in young sedentary males. European heart journal. 1995;16(12):1995-2001.
37.        Khademi A., Tofiqi A., Tolouei Azar C: The effect of resistance training, aerobics and parallelism on some factors affecting blood homeostasis, International Conference on Physical Education, Nutrition and Sports Medicine Type of Conference: Non-Governmental Organizations and Centers, Mashhad University of Medical Sciences, Salman Institute of Higher Education, 1398, Volume 1 and COI Code Article: CONFPN01_068
38.        Smith DL, Fernhall B. Advanced cardiovascular exercise physiology: Human Kinetics; 2011.
39.        Hilberg T, Gläser D, Reckhart C, Prasa D, Stürzebecher J, Gabriel HH. Blood coagulation and fibrinolysis after long-duration treadmill exercise controlled by individual anaerobic threshold. European journal of applied physiology. 2003;90(5):639-42.
40.        El-Sayed M, Lin X, Rattu A. Blood coagulation and fibrinolysis at rest and in response to maximal exercise before and after a physical conditioning programme. Blood coagulation & fibrinolysis: an international journal in haemostasis and thrombosis. 1995;6(8):747-52.
دوره 8، شماره 1
فروردین 1400
صفحه 110-119
  • تاریخ دریافت: 02 مرداد 1400
  • تاریخ بازنگری: 01 شهریور 1400
  • تاریخ پذیرش: 13 شهریور 1400
  • تاریخ اولین انتشار: 13 شهریور 1400