1. Strissel KJ, Stancheva Z, Miyoshi H, Perfield JW, DeFuria J, Jick Z, et al. Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes. 2007;56(12):2910-8.
2. Lafontan M. Adipose tissue and adipocyte dysregulation. Diabetes & metabolism. 2014;40(1):16-28.
3. Spalding KL, Arner E, Westermark PO, Bernard S, Buchholz BA, Bergmann O, et al. Dynamics of fat cell turnover in humans. Nature. 2008;453(7196):783-7.
4. Van Gaal LF, Mertens IL, Christophe E. Mechanisms linking obesity with cardiovascular disease. Nature. 2006;444(7121):875-80.
5. Hall JE. The kidney, hypertension, and obesity. Hypertension (Dallas, Tex : 1979). 2003;41(3):625-33.
6. Kotsis V, Stabouli S, Bouldin M, Low A, Toumanidis S, Zakopoulos N. Impact of obesity on 24-hour ambulatory blood pressure and hypertension. Hypertension (Dallas, Tex : 1979). 2005;45(4):602-7.
7. Stabouli S, Kotsis V, Papamichael C, Constantopoulos A, Zakopoulos N. Adolescent obesity is associated with high ambulatory blood pressure and increased carotid intimal-medial thickness. The Journal of pediatrics. 2005;147(5):651-6.
8. Tanaka M. Improving obesity and blood pressure. Hypertension Research. 2020;43(2):79-89.
9. Villareal DT, Chode S, Parimi N, Sinacore DR, Hilton T, Armamento-Villareal R, et al. Weight loss, exercise, or both and physical function in obese older adults. New England Journal of Medicine. 2011;364(13):1218-29.
10. Bouchonville M, Armamento-Villareal R, Shah K, Napoli N, Sinacore DR, Qualls C, et al. Weight loss, exercise or both and cardiometabolic risk factors in obese older adults: results of a randomized controlled trial. International journal of obesity. 2014;38(3):423-31.
11. Dezhkam N, Rezaeian N. Effect of Six Weeks of Aerobic Training on Meteorin Like Factor Response and Insulin Resistance Index in Overweight and Obese Young Women. Journal of Applied Health Studies in Sport Physiology. 2021;8(1):28-35.
12. Jakicic JM, Clark K, Coleman E, Donnelly JE, Foreyt J, Melanson E, et al. Appropriate intervention strategies for weight loss and prevention of weight regain for adults. Medicine & Science in Sports & Exercise. 2001.
13. Johns DJ, Hartmann-Boyce J, Jebb SA, Aveyard P, Group BWMR. Diet or exercise interventions vs combined behavioral weight management programs: a systematic review and meta-analysis of direct comparisons. Journal of the Academy of Nutrition and Dietetics. 2014;114(10):1557-68.
14. DiPietro L, Stachenfeld NS. Exercise treatment of obesity. Endotext [Internet]. 2017.
15. Catenacci VA, Ogden LG, Stuht J, Phelan S, Wing RR, Hill JO, et al. Physical activity patterns in the national weight control registry. Obesity. 2008;16(1):153-61.
16. MacLean PS, Higgins JA, Wyatt HR, Melanson EL, Johnson GC, Jackman MR, et al. Regular exercise attenuates the metabolic drive to regain weight after long-term weight loss. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2009;297(3):R793-R802.
17. King NA, Hopkins M, Caudwell P, Stubbs RJ, Blundell JE. Beneficial effects of exercise: shifting the focus from body weight to other markers of health. British journal of sports medicine. 2009;43(12):924-7.
18. Jakicic JM, Rogers RJ, Davis KK, Collins KA. Role of physical activity and exercise in treating patients with overweight and obesity. Clinical chemistry. 2018;64(1):99-107.
19. Sari-Sarraf V, Amirsasan R, Parnian Khajehdizaj N. Effects of HIIT and MICT Combined with ICR on FM and LBM in Overweight Women. Journal of Applied Health Studies in Sport Physiology. 2020;7(2):20-8.
20. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. Jama. 2010;303(3):235-41.
21. Cornelissen VA, Smart NA. Exercise training for blood pressure: a systematic review and meta‐analysis. Journal of the American heart association. 2013;2(1):e004473.
22. Saneei P, Salehi-Abargouei A, Esmaillzadeh A, Azadbakht L. Influence of Dietary Approaches to Stop Hypertension (DASH) diet on blood pressure: a systematic review and meta-analysis on randomized controlled trials. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2014;24(12):1253-61.
23. Gay HC, Rao SG, Vaccarino V, Ali MK. Effects of Different Dietary Interventions on Blood Pressure: Systematic Review and Meta-Analysis of Randomized Controlled Trials. Hypertension (Dallas, Tex : 1979). 2016;67(4):733-9.
24. Wan X, Wang W, Liu J, Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC medical research methodology. 2014;14(1):1-13.
25. Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC medical research methodology. 2005;5(1):1-10.
26. Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. Cochrane handbook for systematic reviews of interventions: John Wiley & Sons; 2019.
27. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. Bmj. 2003;327(7414):557-60.
28. Khalafi M, Malandish A, Rosenkranz SK, Ravasi AA. Effect of resistance training with and without caloric restriction on visceral fat: A systemic review and meta‐analysis. Obesity Reviews. 2021:e13275.
29. Khalafi M, Symonds ME, Akbari A. The impact of exercise training versus caloric restriction on inflammation markers: a systemic review and meta-analysis. Critical Reviews in Food Science and Nutrition. 2021:1-16.
30. Vandenbroucke JP. Bias in meta-analysis detected by a simple, graphical test. Experts' views are still needed. BMJ: British Medical Journal. 1998;316(7129):469.
31. Khalafi M, Symonds ME. The impact of high‐intensity interval training on inflammatory markers in metabolic disorders: A meta‐analysis. Scandinavian Journal of Medicine & Science in Sports. 2020;30(11):2020-36.
32. Said MA, Abdelmoneem M, Alibrahim MC, Elsebee MA, Kotb AAH. Effects of diet versus diet plus aerobic and resistance exercise on metabolic syndrome in obese young men. Journal of Exercise Science & Fitness. 2020;18(3):101-8.
33. Murakami T, Horigome H, Tanaka K, Nakata Y, Katayama Y, Matsui A. Effects of diet with or without exercise on leptin and anticoagulation proteins levels in obesity. Blood coagulation & fibrinolysis. 2007;18(5):389-94.
34. Nordstrand N, Gjevestad E, Hertel J, Johnson L, Saltvedt E, Røislien J, et al. Arterial stiffness, lifestyle intervention and a low‐calorie diet in morbidly obese patients—A nonrandomized clinical trial. Obesity. 2013;21(4):690-7.
35. Anderssen S, Holme I, Urdal P, Hjermann I. Diet and exercise intervention have favourable effects on blood pressure in mild hypertensives: the Oslo Diet and Exercise Study (ODES). Blood Pressure. 1995;4(6):343-9.
36. Andrews R, Cooper A, Montgomery A, Norcross A, Peters T, Sharp D, et al. Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial. The Lancet. 2011;378(9786):129-39.
37. Balkestein EJ, van Aggel-Leijssen DP, van Baak MA, Struijker-Boudier HA, Van Bortel LM. The effect of weight loss with or without exercise training on large artery compliance in healthy obese men. Journal of hypertension. 1999;17(12):1831-5.
38. Christiansen T, Paulsen SK, Bruun JM, Pedersen SB, Richelsen B. Exercise training versus diet-induced weight-loss on metabolic risk factors and inflammatory markers in obese subjects: a 12-week randomized intervention study. American Journal of Physiology-Endocrinology and Metabolism. 2010;298(4):E824-E31.
39. Cooper JN, Columbus ML, Shields KJ, Asubonteng J, Meyer ML, Sutton-Tyrrell K, et al. Effects of an intensive behavioral weight loss intervention consisting of caloric restriction with or without physical activity on common carotid artery remodeling in severely obese adults. Metabolism: clinical and experimental. 2012;61(11):1589-97.
40. Dengel DR, Galecki AT, Hagberg JM, Pratley RE. The independent and combined effects of weight loss and aerobic exercise on blood pressure and oral glucose tolerance in older men. American journal of hypertension. 1998;11(12):1405-12.
41. Fernández JM, Rosado-Álvarez D, Da Silva Grigoletto ME, Rangel-Zúñiga OA, Landaeta-Díaz LL, Caballero-Villarraso J, et al. Moderate-to-high-intensity training and a hypocaloric Mediterranean diet enhance endothelial progenitor cells and fitness in subjects with the metabolic syndrome. Clinical Science. 2012;123(6):361-73.
42. Gordon NF, Scott CB, Levine BD. Comparison of single versus multiple lifestyle interventions: are the antihypertensive effects of exercise training and diet-induced weight loss additive? The American journal of cardiology. 1997;79(6):763-7.
43. Kleist B, Wahrburg U, Stehle P, Schomaker R, Greiwing A, Stoffel-Wagner B, et al. Moderate walking enhances the effects of an energy-restricted diet on fat mass loss and serum insulin in overweight and obese adults in a 12-week randomized controlled trial. The Journal of nutrition. 2017;147(10):1875-84.
44. Lefevre M, Redman LM, Heilbronn LK, Smith JV, Martin CK, Rood JC, et al. Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis. 2009;203(1):206-13.
45. Masuo K, Rakugi H, Ogihara T, Lambert GW. Different mechanisms in weight loss-induced blood pressure reduction between a calorie-restricted diet and exercise. Hypertension Research. 2012;35(1):41-7.
46. Okura T, Nakata Y, Lee D, Ohkawara K, Tanaka K. Effects of aerobic exercise and obesity phenotype on abdominal fat reduction in response to weight loss. International journal of obesity. 2005;29(10):1259-66.
47. Ryan AS, Ge S, Blumenthal JB, Serra MC, Prior SJ, Goldberg AP. Aerobic exercise and weight loss reduce vascular markers of inflammation and improve insulin sensitivity in obese women. Journal of the American Geriatrics Society. 2014;62(4):607-14.
48. Ryan AS. Improvements in insulin sensitivity after aerobic exercise and weight loss in older women with a history of gestational diabetes and type 2 diabetes mellitus. Endocrine research. 2016;41(2):132-41.
49. Snel M, Gastaldelli A, Ouwens DM, Hesselink MK, Schaart G, Buzzigoli E, et al. Effects of adding exercise to a 16-week very low-calorie diet in obese, insulin-dependent type 2 diabetes mellitus patients. The Journal of Clinical Endocrinology & Metabolism. 2012;97(7):2512-20.
50. Straznicky NE, Lambert EA, Nestel PJ, McGrane MT, Dawood T, Schlaich MP, et al. Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects. Diabetes. 2010;59(1):71-9.
51. Weiss EP, Albert SG, Reeds DN, Kress KS, McDaniel JL, Klein S, et al. Effects of matched weight loss from calorie restriction, exercise, or both on cardiovascular disease risk factors: a randomized intervention trial. The American journal of clinical nutrition. 2016;104(3):576-86.
52. Wycherley T, Brinkworth GD, Noakes M, Buckley J, Clifton P. Effect of caloric restriction with and without exercise training on oxidative stress and endothelial function in obese subjects with type 2 diabetes. Diabetes, Obesity and Metabolism. 2008;10(11):1062-73.
53. Yoshimura E, Kumahara H, Tobina T, Matsuda T, Watabe K, Matono S, et al. Aerobic exercise attenuates the loss of skeletal muscle during energy restriction in adults with visceral adiposity. Obesity Facts. 2014;7(1):26-35.
54. Nybacka Å, Hellström PM, Hirschberg AL. Increased fibre and reduced trans fatty acid intake are primary predictors of metabolic improvement in overweight polycystic ovary syndrome—Substudy of randomized trial between diet, exercise and diet plus exercise for weight control. Clinical endocrinology. 2017;87(6):680-8.
55. Oh M, Kim S, An K-Y, Min J, Yang HI, Lee J, et al. Effects of alternate day calorie restriction and exercise on cardio-metabolic risk factors in overweight and obese adults: an exploratory randomized controlled study. BMC public health. 2018;18(1):1-10.
56. Otten J, Andersson J, Ståhl J, Stomby A, Saleh A, Waling M, et al. Exercise training adds cardiometabolic benefits of a Paleolithic diet in type 2 diabetes mellitus. Journal of the American Heart Association. 2019;8(2):e010634.
57. Shah K, Stufflebam A, Hilton TN, Sinacore DR, Klein S, Villareal DT. Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity. 2009;17(12):2162-8.
58. Svendsen OL, Hassager C, Christiansen C. Effect of an energy-restrictive diet, with or without exercise, on lean tissue mass, resting metabolic rate, cardiovascular risk factors, and bone in overweight postmenopausal women. The American journal of medicine. 1993;95(2):131-40.
59. Brochu M, Malita MF, Messier V, Doucet E, Strychar I, Lavoie J-M, et al. Resistance training does not contribute to improving the metabolic profile after a 6-month weight loss program in overweight and obese postmenopausal women. The Journal of Clinical Endocrinology & Metabolism. 2009;94(9):3226-33.
60. Dunstan DW, Daly RM, Owen N, Jolley D, De Courten M, Shaw J, et al. High-intensity resistance training improves glycemic control in older patients with type 2 diabetes. Diabetes care. 2002;25(10):1729-36.
61. Figueroa A, Vicil F, Sanchez-Gonzalez MA, Wong A, Ormsbee MJ, Hooshmand S, et al. Effects of diet and/or low-intensity resistance exercise training on arterial stiffness, adiposity, and lean mass in obese postmenopausal women. American journal of hypertension. 2013;26(3):416-23.
62. Sénéchal M, Bouchard DR, Dionne IJ, Brochu M. The effects of lifestyle interventions in dynapenic-obese postmenopausal women. Menopause. 2012;19(9):1015-21.
63. Wycherley TP, Noakes M, Clifton PM, Cleanthous X, Keogh JB, Brinkworth GD. A high-protein diet with resistance exercise training improves weight loss and body composition in overweight and obese patients with type 2 diabetes. Diabetes care. 2010;33(5):969-76.
64. Brinkley TE, Wang X, Kume N, Mitsuoka H, Nicklas BJ. Caloric restriction, aerobic exercise training and soluble lectin-like oxidized LDL receptor-1 levels in overweight and obese post-menopausal women. International journal of obesity. 2011;35(6):793-9.
65. Okura T, Nakata Y, Tanaka K. Effects of exercise intensity on physical fitness and risk factors for coronary heart disease. Obesity research. 2003;11(9):1131-9.
66. Fogelholm M, Kukkonen-Harjula K, Nenonen A, Pasanen M. Effects of walking training on weight maintenance after a very-low-energy diet in premenopausal obese women: a randomized controlled trial. Archives of Internal Medicine. 2000;160(14):2177-84.
67. Thomson RL, Buckley JD, Noakes M, Clifton PM, Norman RJ, Brinkworth GD. The effect of a hypocaloric diet with and without exercise training on body composition, cardiometabolic risk profile, and reproductive function in overweight and obese women with polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism. 2008;93(9):3373-80.
68. Geliebter A, Ochner CN, Dambkowski CL, Hashim SA. Obesity-related hormones and metabolic risk factors: a randomized trial of diet plus either strength or aerobic training versus diet alone in overweight participants. Journal of diabetes and obesity. 2014;1(1):1.
69. Meckling KA, Sherfey R. A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women. Applied physiology, nutrition, and metabolism. 2007;32(4):743-52.
70. Bray GA, Frühbeck G, Ryan DH, Wilding JP. Management of obesity. The Lancet. 2016;387(10031):1947-56.
71. Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension (Dallas, Tex : 1979). 2003;42(5):878-84.
72. Staessen J, Fagard R, Amery A. The relationship between body weight and blood pressure. Journal of human hypertension. 1988;2(4):207-17.
73. Mertens IL, Van Gaal LF. Overweight, obesity, and blood pressure: the effects of modest weight reduction. Obesity research. 2000;8(3):270-8.
74. Koh H, Hayashi T, Sato KK, Harita N, Maeda I, Nishizawa Y, et al. Visceral adiposity, not abdominal subcutaneous fat area, is associated with high blood pressure in Japanese men: the Ohtori study. Hypertension Research. 2011;34(5):565-72.
75. Hayashi T, Boyko EJ, Leonetti DL, McNeely MJ, Newell-Morris L, Kahn SE, et al. Visceral adiposity is an independent predictor of incident hypertension in Japanese Americans. Annals of internal medicine. 2004;140(12):992-1000.
76. Rhéaume C, Arsenault BJ, Bélanger S, Pérusse L, Tremblay A, Bouchard C, et al. Low cardiorespiratory fitness levels and elevated blood pressure: what is the contribution of visceral adiposity? Hypertension (Dallas, Tex : 1979). 2009;54(1):91-7.
77. Fisher G, Hyatt TC, Hunter GR, Oster RA, Desmond RA, Gower BA. Effect of diet with and without exercise training on markers of inflammation and fat distribution in overweight women. Obesity. 2011;19(6):1131-6.
78. Satou R, Penrose H, Navar LG. Inflammation as a regulator of the renin-angiotensin system and blood pressure. Current hypertension reports. 2018;20(12):1-9.
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