بررسی تاثیر فعالیت بدنی بر تروپونین‌های قلبی: یک مرور سیستماتیک

نوع مقاله : مقاله مروری Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 استادیار، گروه فیزیولوژی ورزشی، واحد کرمانشاه، دانشگاه آزاد اسلامی، کرمانشاه، ایران.

2 دانشجوی دکتری فیزیولوژی ورزشی، واحد کرمانشاه، دانشگاه آزاد اسلامی، کرمانشاه، ایران.

3 متخصص قلب و عروق، فلوشیپ اینترونشنال کاردیولوژی، استادیار و عضو هیئت علمی دانشگاه علوم پزشکی کرمانشاه، مرکز تحقیقات قلب و عروق،

10.22049/jahssp.2021.27158.1346

چکیده

هدف: انفارکتوس حاد میوکارد از شایع­ترین بیماری­های قلبی است، تروپونین I و تروپونین T نشانگرهای زیستی برای تشخیص نکروز سلول­های قلبی در بیماران مبتلا به سندرم کرونری حاد هستند. علاوه بر سکته قلبی، ورزش و فعالیت بدنی شدید می­تواند باعث افزایش حاد تروپونین I و تروپونین T شود. هدف از پژوهش حاضر، مروری سیستماتیک بر روی مطالعات انجام شده جهت بررسی اثر فعالیت­های بدنی و ورزش بر تروپونین­های قلبی می­باشد. روش شناسی: مطالعات مربوط به پاسخ تروپونین I و تروپونین T به ورزش و فعالیت­های بدنی در مقالات منتشر شده را در Springer, Hindawi,PubMed,Google Scholar, Scopus,  ,SID وISC  با استفاده از کلید واژه­های Exercise induced troponin, Exercise-induced cardiac injury, Troponin release, Exercise and troponin و Myocardial infarction and troponin جستجو کردیم. یافته­ها: در مطالعات مربوط به مسابقات ماراتن، 11 مطالعه بررسی شد، تعداد آزمودنی­ها 881 نفر بودند، در 67 درصد افراد ، افزایش تروپونین مشاهده شده است، در مسابقات دو استقامتی 4 مقاله بررسی شد، تعداد ورزشکاران 118 نفر بودند، که در 65 درصد افراد افزایش تروپونین دیده شده است. در 5 مطالعه در ارتباط با تاثیر پیاده روی بر تروپونین، 194 ورزشکار تحت مطالعه قرار گرفته­اند که در 8 درصد موارد افزایش تروپونین مشاهده شده است. در بررسی 3 مطالعه در ورزش سه گانه مردان هم، 58 نفر تحت مطالعه قرار گرفتند که در 69 درصد موارد افزایش تروپونین رخ داده است. همچنین در 5 مطالعه­ی تاثیر ورزش دوچرخه سواری بر تروپونین، 94 نفر تحت مطالعه قرار گرفتند که در 27 درصد از ورزشکاران افزایش تروپونین دیده شده است. نتیجه گیری: تروپونین I و تروپونین T در ورزش طولانی مدت یا شدید بایستی به دقت بررسی شود، هر چه شدت و زمان ورزش بیشتر باشد، افزایش تروپونین نیز بیشتر است. در چنین مواقعی احتمال خطر سکته قلبی وجود دارد. آگاهی از تفاوت زمان تقریبی افزایش و کاهش تروپونین بعد از سکته قلبی و ورزش می­تواند در تشخیص پاتولوژیک یا فیزیولوژیک بودن افزایش تروپونین کمک کننده باشد.

کلیدواژه‌ها

عنوان مقاله [English]

Investigation Effect of Exercise and Physical Activity on Cardiac Troponins: A Systematic Review

نویسندگان [English]

  • Mehran Ghahramani 1
  • Peyman Kaikhosro Doulatyari 2
  • Mohammad Rouzbahani 3
1 Assistant Professor , Department of Exercise Physiology,Kermanshah Branch, Islamic Azad University, Kermanshah, Iran
2 Ph.D Student Department of Exercise Physiology, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran.
3 Interventional cardiologist, assistant professor of Cardiology Kermanshah University of Medical Sciences, Cardiovascular Reserch Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
چکیده [English]

Aim:  Acute myocardial infarction is one of the most common heart diseases. Troponin I and troponin T are biomarkers for the diagnosis of cardiac cell necrosis in patients with acute coronary syndrome.In addition to myocardial infarction, exercise and strenuous physical activity can cause acute increases in troponin I and troponin T. The purpose of this study was to provide a systematic review of studies on the effects of physical activity and exercise on cardiac troponins. Methods: Search for studies on troponin I and troponin T in exercise and physical activity in the reputable databases Springer, Hindawi, PubMed, Google Scholar, Scopus, SID and ISC using the keyword Exercise induced troponin, Exercise-induced cardiac injury, Troponin release, Exercise and troponin, and Myocardial infarction and troponin were performed. Results: In a review of marathon studies showing 11 studies were reviewed, the number of athletes was 881, in 593 (67%), increase in troponin was observed, In the endurance Running competitions with the mentioned conditions, 4 articles were reviewed, The number of athletes was 118, with a 65% increase in troponin. In 5 studies related to the effect of walking on troponin, 194 athletes were studied, which in 8% of cases showed increase in troponin. In a review of three studies in the Ironman Triathlon, 58 athletes were studied, with a 69% increase in troponin. Also, in 5 studies on the effect of cycling exercise on troponin, 94 athletes were studied, As a result, increase in troponin was seen in 27% of athletes. Conclusion: Troponin I and troponin T in prolonged or strenuous exercise should be monitored carefully. The more intense and time the exercise, The increase in troponin is also greater. In such cases, there is a risk of Myocardial infarction. Knowing the difference between the approximate time of increase and decrease of troponin after myocardial infarction and exercise can be helpful in diagnosing whether the increase in troponin is pathological or physiological.

کلیدواژه‌ها [English]

  • Myocardial infarction
  • Physical activity
  • Troponin I
  • Troponin T

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 8، شماره 1
فروردین 1400
صفحه 12-20

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سابقه مقاله

  • تاریخ دریافت: 08 اسفند 1399
  • تاریخ بازنگری: 28 فروردین 1400
  • تاریخ پذیرش: 14 اردیبهشت 1400

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