تاثیر مصرف کوتاه مدت سیترولین مالات بر نیتریک اکساید، لاکتات و شاخص‌های گردش خونی آسیب عضلانی در مردان سالم تمرین کرده

نوع مقاله : مقاله پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزش، گروه فیزیولوژی ورزش، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

2 استاد فیزیولوژی ورزش، گروه فیزیولوژی ورزش، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

10.22049/jassp.2020.26862.1314

چکیده

هدف: سیترولین مالات (CM) یک مکمل غذایی است که با هدف بهبود عملکرد ورزشی از طریق افزایش تولید نیتریک اکساید (NO) استفاده می­شود. هدف از پژوهش حاضر بررسی تاثیر مصرف کوتاه مدت CM بر بر عملکرد ورزشی و مقدار نیتریک اکساید، لاکتات و شاخص‌های گردش خونی آسیب عضلانی در مردان سالم تمرین کرده بود. روش­ شناسی: در پژوهشی تجربی با طرح تصادفی معکوس، هشت آزمودنی پس از شرکت در جلسه اول جهت اندازه­گیری ویژگی های آنتروپومتری و فاکتورهای عملکردی پایه، سه جلسه دارونما (8 گرم دکستروز) و یا مکمل CM  (8 گرم) را به صورت دوسوکور دریافت کردند و در طی سه مرحله، استقامت عضلانی، استقامت هوازی و توان بی­هوازی با آزمون­های شنا­سوئدی، کوپر و رست سنجیده شدند. داده­ها با استفاده از آزمون­های تحلیل واریانس مکرر و آزمون تعقیبی بونفرونی در سطح معناداری 0/05 مقایسه شدند. یافته ­ها: مصرف CM به کاهش معنادار پاسخ CK به فعالیت ورزشی (0/041=ϼ) افزایش پاسخ NO به فعالیت ورزشی(0/006=ϼ)، افزایش میانگین توان بی­هوازی ( 0/037=ϼ) و افزایش استقامت عضلانی (0/005=ϼ) منجر ­­شد. با این حال اثر معناداری بر توان بی­هوازی اوج( 0/13=ϼ) و استقامت هوازی (0/08=ϼ) و پاسخ LDH و لاکتات به فعالیت ورزشی (0/99=ϼ) ایجاد نکرد. نتیجه ­گیری: بهره گیری کوتاه مدت از مکمل CM احتمالا به بهبود عملکرد بی­هوازی، رگ گشایی و کاهش آسیب­های عضلانی بیانجامد.

کلیدواژه‌ها


عنوان مقاله [English]

Effects of Short Term Citrulline Malate Supplementation on Circulatory Nitric Oxide, Lactate and Muscle Damage Markers in Healthy Trained Men

نویسندگان [English]

  • AhmadReza Eshaghian 1
  • Ali Asghar Ravasi 2
  • Abbas Ali Gaeini 2
1 M.Sc, Department of Exercise Physiology, Faculty of Physical Education, University of Tehran, Tehran, Iran
2 Professor, Department of Exercise Physiology, Faculty of Physical Education, University of Tehran, Tehran, Iran
چکیده [English]

Aim: Citrulline malate (CM) as a dietary supplement is used to enhance exercise performance vua increasing nitric oxide production. The aim of this study was to investigate the effect of short term CM supplementation on exercise performance and circulatory nitric oxide, lactate and muscle damage markers in healthy trained men. Methods: In a cross over designed experimental study, eight subjects consumed CM or placebo (Starch) or (8g) for three consecutive days in a double blind order. Muscular endurance with both aerobic and anaerobic power were measured by pushup, cooper and RAST tests respectively. The data were compared using ANOVA for repeated measurements and Bonfroni post hoc tests, at a significance level of 0/05. Results: CM consumption significantly reduced CK response to exercise (ϼ=0.041), while increased NO response to exercise (ϼ=0.006), average anaerobic power (ϼ=0.037) and muscular endurance (ϼ=0.005). Nevertheless, it had’nt significant effects on LDH and lactate response to exercise (ϼ=0.99) or aerobic (ϼ=0.08) and anaerobic power (ϼ=0.13). Conclusions: Short term CM supplementation may lead to an improved anaerobic performance, vasodilation as well as a lowered level of muscular damage.

کلیدواژه‌ها [English]

  • Ergogenic
  • Muscle Damage
  • Citrulline malate
  • Nitric oxide
 
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