تاثیر تمرینات اسپارک بر عامل نروتروفیک مشتق از مغز، مهارت های حرکتی ظریف و درشت در کودکان کم توان ذهنی آموزش پذیر

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 دانشجوی دکترای فیزیولوژی ورزشی، گروه تربیت بدنی، دانشکده هنر و معماری، دانشگاه آزاداسلامی، واحد شیراز، شیراز، ایران

2 دانشیار، گروه تربیت بدنی، دانشکده هنر و معماری، دانشگاه آزاداسلامی، واحد شیراز، شیراز، ایران

3 استادیار رفتار حرکتی، گروه رفتار حرکتی، دانشکده علوم ورزشی، دانشگاه بوعلی سینا، همدان، ایران

4 استادیار گروه رفتار حرکتی ، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی، تهران، ایران.

10.22049/jassp.2020.26796.1302

چکیده

هدف: هدف از این پژوهش تعیین تاثیر یک دوره تمرینات اسپارک بر عامل نروتروفیک مشتق از مغز (BDNF) و مهارت های حرکتی ظریف و درشت در کودکان کم توان ذهنی آموزش پذیر بود. روش‌شناسی:  20 دانش آموز پسر کم توان ذهنی 7 تا 9 سالۀ به صورت تصادفی به دو گروه تجربی (10 نفر) و کنترل (10 نفر) تقسیم شدند. گروه تجربی یک برنامۀ منتخب اسپارک را به مدت 12 هفته هر هفته 3 جلسۀ 45 دقیقه ای اجرا کردند. قبل و بعد از مداخلۀ برنامه مهارت های ظریف و درشت و سطح BDNF تمام آزمودنی ها اندازه گیری شد. جهت تجزیه و تحلیل داده ها از آزمون تحلیل واریانس چند متغیره (مانوا) با اندازه گیری های مکرر و در سطح معنی داری 0/05=α استفاده شد. یافته ها: در پیش آزمون تفاوت معنی داری بین دو گروه تجربی و کنترل در هیچ یک از متغیرهای اندازه گیری شده وجود ندارد. پس از اعمال دوره تمرینی، گروه تجربی به لحاظ فاکتورهای خونی BDNF  بالاتر و در مهارت های حرکتی ظریف وضعیت بهتر و معنی داری نسبت به گروه کنترل داشت. درباره مهارت های حرکتی درشت، تفاوت معنی داری بین گروه های کنترل و تجربی در پس آزمون وجود نداشت. نتیجه‌گیری: برنامه منتخب اسپارک باعث افزایش سطح BDNF و بهبود مهارت های حرکتی ظریف در دانش آموزان کم توان ذهنی آموزش پذیر می شود، اما تأثیر معنی داری بر مهارت های درشت ندارد که به نظر می رسد تا حدی به دلیل افزایش BDNF باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Effects of SPARK Program on Fine and Gross Motor Skills and BDNF in Educable Intellectual Disabled Children

نویسندگان [English]

  • Hamid Arvin 1
  • Mehrzad Moghadasi 2
  • Hassan Rohbanfard 3
  • Saeed Arsham 4
1 PhD Student in Exercise Physiology,Department of Physical Education, Faculty of Art and Architecture, Islamic Azad University, Shiraz Branch,Shiraz Iran
2 Associate Professor, Department of physical education, Faculty of Art and Architecture, Islamic Azad University, Shiraz Branch, Shiraz, Iran
3 Assistant Professor of Motor Behavior,Faculty of Sports Sciences, BU-ALI-SINA University, Hamadan, Iran
4 Assistant Professor of Motor Behavior,Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran
چکیده [English]

Aim: The purpose of this study was to determine the effects of a curriculum known as Sports, Play and Active Recreation for Kids (SPARK) on fine and gross motor skills and brain-derived neurotrophic factor (BDNF) in educable intellectual disabled children. Methods: Twenty intellectual disabled boy students aged 7 to 9 years were randomly divided into experimental (n=10) and control (n=10) groups. The experimental group performed a selected SPARK program 3 days a week for 12 weeks. Fine and gross motor skills and BDNF level were measured before and after the intervention. Multivariate analysis of variance (MANOVA) with repeated measures was used for data analysis (α = 0.05). Results: Data revealed that there were no significant differences between two groups in any of the measured variables at the baseline. After the intervention, the experimental group performed significantly better in fine motor skills and had higher level of BDNF as compared to the control group. Regarding gross motor skills, there were no significant differences between experimental and control groups in the post-test. Conclusion: The selected SPARK protocol increases BDNF level and improves fine motor skills however it has not significant effect on gross motor skills in the educable intellectual disabled boy students; which could be partially attributed to an increased BDNF levels.

کلیدواژه‌ها [English]

  • BDNF
  • Intellectual Disabled Children
  • Fine & Gross Motor Skills
  • SPARK Training
  1.  

    1. Duristine J L, More G M, Painter P L, Robert O S. "ACSM,s Exercise Management for Persons with  Chronic Diseases and Disabilities". Human Kinetics 2009; 359-367.
    2. Ghasemzadeh S‚ Naghdi N‚ Afrouz Gh. The impact of games and activities evil-based Share project on the motor skills in children’s slow moving. Motor Learning and Development-Sporting 2017; 9(3):445-456. (Persian).
    3. Khalil Tahmasebi R‚ Ghasemi G‚ Faramarzi S. Effect of rebound exercises on the static and dynamic balance of educable mentally retarded children. Research in Rehabilitation Sciences 2013; 9(6):1050-1062. (Persian).
    4. Ghaji H‚ Kordi H‚ Farrokhi A‚ Bahram A. The effect of local native games and routine games on the development of manipulation skills in educable mentally retarded boys. Finding 2013; 15(5): 61-71. (Persian).
    5. Pahlavanian A‚ Rasoulzadeh M‚ Amozadeh Khalili M. Comparison of motor skills of mentally retarded and normal children rational with age of 6-7 years. Koomesh 2012; 13(4): 460-465. (Persian).   
    6. Gallahue DL, Ozmun JC. Understanding Motor Development: Infant, Children, Adolescents, Adults. 7th ed. Newyork (NY): McGraw-Hill; 2011.
    7. Fujimura H, Altor C A,Chen R, Nakamura T, Kambayashi J, et al. "Brain –Derived Neurotrophic Factoe is Stored in Human Platelets and Released by Agonist Stimulation". Thromb Haemost 2002; 87: 728-734.
    8. Ernfors P‚ Kucera J‚ Lee KF‚ Loring J‚ Jaenisch R. Studies on the physiological role of the brain-derived neurotrophic factor and neurotrophin-3 in knockout mice. The Inter Jour of Deve Bio. 1995; 39 (5): 799-807.
    9. Gharai F‚ Arabameri E‚ Humaniyan D. The effect of environmental enrichment (perceptual-motor and musical) on the age-related equilibrium of fine and gross motor in 5-8 month-old infants. Motor Learning and Development-Sporting 2014; 6(1): 75-89. (Persian).
    10. Rusanescu G‚ Mao J. Immature spinal cord neurons are dynamic regulators of adult nociceptive sensitivity. Jour of Cell and Mole Med 2015; 19 (10): 2352-64.
    11. Paterson S L, Abel T, Deuel T A, Martin KC, Rose J C, Kandel E R. "Recombinant BDNF Resurs Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice". Neuron 1996; 16: 1137-1145.
    12. Cotman CW, Engesser – Cesar C (2002). Exercise Enhances and Protects Brain Function. Exerc Spot Sci Rev; 30: 75-79.
    13. Zhong L‚ Yan CH‚ Lu CQ‚ Xu J‚ Huang H‚ Shen XM. Calmodulin activation is required for the enhancement of hippocampal neurogenesis following environmental enrichment. Neurol Res 2009; 31 (7): 707-13.
    14. Maina G‚ Rosso G‚ Zanardini R‚ Bogetto F‚ Gennarelli M‚ Bocchio-Chiavetto L. "Serum levels of Brain-derived neurotrophic factor in drug-naïve obsessive-compulsive patients: a case-control study". Journal of Affective Disorders 2010; 122 (1-2): 174-8.
    15. Zajac MS‚ Pang TY‚ Wong N‚ Weinrich B‚ Leang LS‚ Craig JM‚ Saffery R‚ Hannan AJ. "Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wide-type and pre-motor symptomatic male and female Huntington’s disease mice". Hippocampus 2010; 20(5):621-36.  
    16. Xiu MH‚ Hui L‚ Dang TF‚ Hou TD‚ Zhang CX‚ Zheng YL‚ Chen DC‚ Kosten TR‚ Zhang XY. "Decreased serum BDNF levels in chronic institutionalized schizophrenia on long-term treatment with typical and atypical antipsychotics". Progress in Neuropsychopharmacology & Biological Psychiatry 2009; 33(8): 1508-12.
    17. Brunion AR‚ Lopes M‚ Fregni F. "A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression". The International Journal of Neuropsychopharmacology 2008; 11(8):1169-80.
    18. Dwivedi Y. " Brain-derived neurotrophic factor: role in depression and suicide". Neuropsychiatric Disease and Treatment 2009; 5:433-49.
    19. Aracio O. Chao MV. "Neurotrophins‚ synaptic plasticity and dementia" Current Opinion in Neurology 2007; 17(3): 325-30.
    20. Zuccato C‚ Cattaneo E. " Brain-derived neurotrophic factor in neurodegenerative diseases". Nature Reviews Neurology 2009; 5(6): 311-22.
    21. Zeev Bb‚ Bebbington A‚ Ho G‚ Leonard H‚ De Klerk N‚ Gak E‚ Vecsler M‚ Vecksler M‚ Christodoulou J. "The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome". Neurology 2009; 72(14): 1242-7. 
    22. Mercader JM‚ Fernandez-Aranda F‚ Gratacos M‚ Ribases M‚ Badia A‚ Villarojo C‚ et al. Blood levels of Brain-derived neurotrophic factor correlate with several psychopathological symptoms in anorexia nervosa patients. Neuropsycho 2007; 56 (4): 185-90.
    23. Vargas-Perez H‚ Ting-A Kee R‚ Walton CH‚ Hansen DM‚ Razavi R‚ Clarke L‚ et al. Ventral tegmental area BDNF induces an opiate-dependent-like reward state in naïve rats. Sci 2009; 328 (5935): 1732-4.
    24. Thoenen H‚ Sendtner M. "Neurotrophins : from enthusiastic expectations through sobering experiences to rational therapeutic approaches". Nature Neuroscience. 5 Suppl 2002; 1046-50.
    25. Moghaddasi M‚ Edalatmanesh MA‚ Moini A‚ Nematollahzadeh Mahani M. Effect of 8 weeks resistance training on the among of brain-derived neurotrophic factor in women with multiple sclerosis. Koomesh 2015; 17 (1): 45-57. (Persian).  
    26. Szuhany KL‚ Buatti M‚ Otto MW. A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor. Jour of Psychi Res 2015; 60: 56-64.
    27. Minkyung lee, Jinyoung won, Seonghoon,Yunkyung Hong, Joo-Heon kim, Yonggeun Hong. "Benefits of Physical Exercise for Individuals with Fragile X Syndrome in Human". Journal of Lifestyle Medicin 2015;  5(2),35-38.
    28. Salari Scor M‚ Zarezadeh M‚ Amiri Khorasani M. The effect of 12 weeks of perceptual-motor exercises on the dynamic balance in mentally retarded boys aged 11-14 years. Research in Rehabilitation Sciences 2014; 10(1): 139-150. (Persian).   
    29. John Mohammadi F. The effect of 8 weeks SPARK training on malondiadehyde  and brain-derived neuroyrophic factor in Down syndrome children. Master’s Thesis. Islamic Azad University of Marvdasht Branch 2017.  (Persian).
    30. Parrini M, Ghezzi D, Deidda G, Medrihan L, Castroflorio E, Alberti M, Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome. Sci Rep 2017; 7(1):16825.
    31. Bruininks RH, Bruininks BD. Bruininks-Oseretsky test of motor proficiency. 2nd ed. Minneapolis (MN): NCS Pearson; 2005.
    32. McKenzie TL, Alcaraz JE, Sallis JF, Faucette FN. Effects of a physical education program on children's manipulative skills. Teach Physic Educ 1998; 17 (3): 327-341
    33. Soltani Khadiv K‚ Kamali M‚ Rafiei S‚ Taghizadeh G. A correlation study between Bruiniks-Oseretsky test of motor proficiency and Peabody development motor scale in assessing motor skills of educable retarded children. Res in Rehab Sci 2014; 2 (10): 306-314. (Persian).   
    34. Haywood K, Getchell N. Lifespan motor development. 6th ed. Champaign (IL): Human Kinetics; 2014.
    35. Payne VG, Isaacs LD. Human motor development: A lifespan approach. 8th ed. Newyork (NY): Routledge; 2016.
    36. Zeng N, Ayyub M, Sun H, Wen X, Xiang P, Gao Z. Effects of physical activity on motor skills and cognitive development in early childhood: A systematic review. BioMed Res Inter 2017; 43: 1-13.
    37. Munir KM. The co-occurrence of mental disorders in children and adolescents with intellectual disability/intellectual developmental disorder. Curr Opin Psychiatry 2016; 29(2): 95–102.
    38. Minkyung lee, Jinyoung won, Seonghoon,Yunkyung Hong, Joo-Heon kim, Yonggeun Hong. "Benefits of Physical Exercise for Individuals with Fragile X Syndrome in Human". Journal of Lifestyle Medicin 2015; 5(2),35-38.
    39. Lee IHSeo EJLim IS. Effects of aquatic exercise and CES treatment on the changes of cognitive function, BDNF, IGF-1, and VEGF of persons with intellectual disabilities. J Exerc Nutrition Biochem 2014; 18: 19-24.
    40. Hashimoto K, Iwata Y, Nakamura K, Tsujii M, Tsuchiya KJ, Sekine Y, et al. Reduced serum levels of brain-derived neurotrophic factor in adult male patients with autism. Prog Neuropsychopharmacol Biol Psychiatry 2006; 30: 1529-1531.
    41. Donnelly, C. H. Hillman, D. Castelli et al. “Physical Activity, Fitness, Cognitive Function, and Academic Achievement in Children,” Med & Sci in Sports & Exerc 2016; 48 (6): 1197–1222.
    42. .Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: exercise effect on brain and cognition. Nature Rev Neurosci 2008; 9: 58-65.
    43. Ferris LT, Williams JS, Shen, CL. The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function. Med Sci Sports Exerc 2007; 39: 728-734.
    44. Machado SFilho ASWilbert MBarbieri GAlmeida VGurgel A, et al. Physical exercise as stabilizer for Alzheimer's disease cognitive decline: Current status. Clin Pract Epidemiol Ment Health 2017; 13: 181-184.
    45. Shahbazi M‚ Shayan A‚ Samadi A‚ Nenati Z. The effect of resistant exercise on memory and neurotrophic factors in inactive students. Motor Learning and Development-Sporting 2015; 7(1): 1-19. (Persian).
    46. Isa-Nejad A‚ Parno A‚ Kazemi A‚ Islami R‚ Pieri S‚ Hosseini SA. The effect of regular physical activity on changes in serum level of brain-derived neurotrophic factor‚ IQ and motor proficiency of mentally retarded children. Motor Behavior 2017; 28: 109-128. (Persian).
    47. Hosseinpour Delaware S‚ Behpour N‚ Taadibi V‚ Khani R. Effect of 12 weeks of motor integrated exercises on brain-derived neurotrophic factor in elderly with dementia. Life Sciences of Sports 2017; 9(2): 223-241. (Persian).
    48. Faal Moghanloo H‚ Hosseini F‚ Mikaeli F. The effect of SPARK’s motor program and basketball techniques on improving the motor skills educable mentally retarded boys. Journal of Birjand University of Medial Sciences 2013; 20(3):54-61. (Persian).
    49. Bayani H‚ Mohammadi F‚ Ziafazelzadeh M. Effect of two types of aerobic and anaerobic physical activity on serum levels of nutritional brain-derived factor and cortisol in active men. Sport and Life Sciences 2014; 6(1): 49-57. (Persian).
    50. Ghasempour L‚ Hosseini F‚ Mohammadzadeh H. Influence of emotional-motor integrity training on the development of fine motor skills in mentally retarded children. Disability Studies 2013; 3(1): 27-36. (Persian).
    51. Moutaghed G. The effect of 8 week SPARK exercises on physical fitness in 9-14 year old educable mentally retarded girl in Boyer Ahmad township. Master’s Thesis. Islamic Azad University of Yasouj Branch.2016; (Persian).
    52. Rohbanfard H. The effect of a special motor program on perceptual-motor abilities of 10-13 years-old educational retarded students in Tehran. Master’s thesis. Tehran: University of Tehran. 2006; (In persian).

      1. Kubilay N, Yildirin Y, Kara B. "Effect of balance training and posture Rehabilitasyon". exercises on functional level in mental retardation. Fizyotoraphi 2011;  22(2): 55-64.
      2. Goodway TD, Branta CF. "Influence of a Motor Skill Intervention on Fundemental Motor Skill Development of Disadvantaged Preschool Children". Research quarterly exercise sport 2003; 74(1):36-46.
      3. Yilmaz I, Ergan N, Konukman F, Agbuga B ,Zorba E, Cimen Z. "The effect of  water exercise and swimming on Physical fitness of children with mental retardation. Journal of Human Kinetics" 2009; 21(88):105-111.
      4. Emarati F‚ Namazizadeh M‚ Mokhtari P‚ Mohammadian F. Effect of primary school games on perceptual-motor development and social development in 8-9 year old girls. Research in Rehabilitation Sciences 2011; 7(5): 661-673. (Persian).
      5. Nazari H‚Haydarpour S‚Rahimizadeh S‚Banitalebi A. Effect  of acute plyometric exercise activity with and without vitamin C supplementation on the serum concentration brain-derived neurotrophic factor of inactivity men. Sport Life Sciences 2016; 8(4): 563-574. (Persian).              
      6. Rechards SD, Pilly J, Friz E. "The Use of Sand Tray Techniques by School Counsellors to Assist Children Whit Emotional and Behavioural Problems". The Arts in Psychothrapy 2012; 39(5): 367-73.