تأثیر انواع تمرین تناوبی با شدت بالا بر نیم‌رخ لیپیدی و هومئوستاز گلوکز در زنان میانسال اضافه وزن/چاق

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دکتری فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران.

2 دانشیار فیزیولوژی ورزشی-مولکولی، گروه علوم زیستی ورزش، دانشکده علوم ورزشی و تندرستی، دانشگاه شهید بهشتی، تهران، ایران.

3 استادیار ژنتیک، گروه ژنتیک پزشکی، دانشکده پزشکی، دانشگاه علوم پزشکی و خدمات بهداشتی درمانی تبریز، تبریز، ایران.

10.22049/jassp.2020.14018

چکیده

سابقه و هدف: چاقی به‌عنوان یک چالش جهانی، ناشی از تعادل مثبت انرژی است و به‌کارگیری بهترین پروتکل تمرینی یکی از روش‌های مدیریت وضعیت چاقی و اختلالات مرتبط می‌باشد. بر این اساس، مطالعه حاضر با هدف بررسی تأثیر دو نوع تمرین تناوبی با شدت بالا (HIIT) به‌تنهایی و همراه با تمرین مقاومتی (ترکیبی CHRT) بر عوامل نیم‌رخ لیپیدی، گلوکز، انسولین و مقاومت انسولین در زنان میان‌سال مبتلا به اضافه‌وزن/چاق انجام شد. مواد و روش‌ها: ۲۴ زن میان‌سال اضافه‌وزن/چاق به‌مدت ۸ هفته (۵ روز/هفته) در دو گروه همگن (12 نفری) تمرین HIIT به‌تنهایی و ترکیبی CHRT (3 روز HIIT و 2 روز تمرین مقاومتی) شرکت کردند؛ تمرین HIIT شامل وهله‌های دویدن به‌صورت پنج تکرار چهار دقیقه‌ای با ۸۰ تا ۸۵٪ Vo2max و دو دقیقه استراحت فعال با 60% Vo2max بین تکرارها بود و برنامه تمرین مقاومتی نیز به‌صورت دایره‌ای و با %80-75 1-RM انجام شد. نمونه‌های خونی طی ۴۸ ساعت قبل و بعد از دوره تمرین، جمع‌آوری شد، سپس داده‌های حاصل با استفاده از نرم افزار SPSS تجزیه تحلیل شد. یافته‌ها: یافته‌ها نشان دادند که کاهش توده بدنی و WHR متعاقب پروتکل‌های تمرینی در گروه HIIT معنی‌دار نبود، درصورتی‌که هر دو نوع تمرین منجر به کاهش معنا‌دار درصد چربی بدنی، کلسترول، TG، HDL، LDL، گلوکز، انسولین و مقاومت به انسولین شدند که مقادیر فاکتورهای WHR و نیم‌رخ لیپیدی میان دو گروه تفاوت معنا‌داری داشتند. نتیجه‌گیری: نتایج مطالعه حاضر نشان داد که انجام تمرین CHRT به‌نحو مطلوب‌تری می‌تواند منجر به کاهش وزن و تعدیل عوامل متابولیکی در زنان میان‌سال اضافه‌وزن/چاق شود.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of high intensity interval training on lipid profile and glucose homeostasis in overweight / obese middle-aged women

نویسندگان [English]

  • Zhaleh Pashaei 1
  • Afshar Jafari 2
  • Mohammadreza Alivand 3
1 PhD of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Tabriz University. Tabriz - Iran.
2 Associate Professor in Molecular Exercise Physiology, Department of Sport Biological Sciences, School of Sport Sciences and Health, Shahid Beheshti University, Tehran, Iran.
3 Assistant Professor, Department of Medical Genetics, School of Medicine, Tabriz University of Medical sciences, Tabriz, Iran
چکیده [English]

Background and aim: Obesity is a global challenge that due to the positive energy balance and the use of the best exercise protocol is one of the methods for obesity and related disorders management. Therefore, the present study was conducted to determine the effect of eight-week high- intensity interval training (HIIT) alone and combined with resistance training (CHRT) on lipid profiles and glucose, insulin and insulin resistance in overweight/ obese middle-aged women. Materials and Methods: Twenty-four middle-aged overweight/obese women participated in two homogeneous HIIT (5 days/week, n=12) and CHRT (3 days/week HIIT with 2 days/week resistance training, n=12) groups for eight-week. The HIIT protocol consisted of alternating bouts of high-intensity exercise at 80%–85% of VO2max with active breaks at 60% of VO2max and resistance training protocol conducted to a circuit-weight training with 75-80% of 1-RM. Blood samples were collected 48 hours before and after the training period, and then the data were analyzed using SPSS software. Results: The findings showed that the reduction of BMI and WHR was not significant in the HIIT group, but body fat%, cholesterol, TG, HDL, LDL, glucose, insulin and insulin resistance significantly decreased in both group, that WHR and lipid profiles were significantly different between the two groups. Conclusion: Results of this study showed that CHRT can lead to weight loss and adjusted metabolic status in middle-aged overweight/obese women.

کلیدواژه‌ها [English]

  • Overweight
  • Obesity
  • High-intensity interval training. lipid profiles and insulin resistance
Avigdor D. A, Fred J. D, Naketa T, Jacqueline T-H, Richard W, Allan G, and Jeanine B. A. (2015). High-Intensity Interval Training without Weight Loss Improves Exercise but not Basal or Insulin-Induced Metabolism in Overweight/Obese African American Women. Journal of Applied Physiology; 119(4): 352–362.

Arslan E, Can S, Demirkan E. (2017). Effect of Short-Term Aerobic and Combined Training Program on Body Composition, Lipids Profile and Psychological Health in Premenopausal Women. Science sports; 32(2):106-118.

Alvarez C, Ramirez-Campillo R, Henriquez-Olguin C, CastroSepulveda M, Carrasco V, Martinez C. (2014). Eight Weeks of Combined High Intensity Intermittent Exercise Normalized Altered Metabolic Parameters in Women. Revista Medica de Chile; 142(4):458–66.

Almenning I, Rieber-Mohn A, Lundgren KM, Shetelig Løvvik T, Garnæs KK, Moholdt T. (2015). Effects of High Intensity Interval Training and Strength Training on Metabolic, Cardiovascular and Hormonal Outcomes in Women with Polycystic Ovary Syndrome: A Pilot Study. PLOS ONE; 10(9): e0138793.

Abedi B, Okhovat E, Banitalebi E. (2016). Comparing the Effects of Intense Sprint and Combined Aerobic-Strength Training on Serum Adiponectin Level and Insulin Resistance among the Women with Type 2 Diabetes.Journal of Kashan University of Medical Sciences; 20(4):352-360.

Arazi H, Joorbonyan A, Asghari E. (2012). Comparison of the Effect of a Combined and Aerobic Training on the Maximum Oxygen Consumption, Lipid Profile, Blood Glucose and Blood Pressure in Middle-Aged Men with Cardiovascular Risk Factors. Journal of Shahid Sadoughi University of Medical Sciences; 20(5):627-638.

Arazi H, Faraji H, Moghadam MG, Samadi A. (2011). Effects of Concurrent Exercise Protocols on Strength, Aerobic Power, Flexibility and Body Composition. Kinesiology; 34(2):155-62. [Full Text in Persian].

Bahrami A, Saremi A. (2011). Effect of Caloric Restriction with or without Aerobic Training on Body Composition, Blood Lipid Profile, Insulin Resistance, and Inflammatory Marker in Middle-Age Obese/Overweight Men. Arak Medical University Journal (AMUJ); 14(56): 11-9.

Cervantes J, Hernández J. (2017). Effect of High-Intensity and Concurrent Training in Body Composition in Costa Rican Overweight and Obese Women. Arch Sports Med; 1(2):65-74.

Cuff DJ, Meneilly GS, Martin A, Ignaszewski A, Tildesley HD, Frohlich JJ. (2003). "Effective Exercise Modality to Reduce Insulin Resistance in Women with Type 2 Diabetes". Diabetes care; 26(11): 2977-2982.

Ciolac E.G, Bocchi E.A, Bortolotto L.A, Carvalho V.O, Greve, JM, Guimarães GV. (2010). Effects of High-Intensity Aerobic Interval Training vs. Moderate Exercise on Hemodynamic, Metabolic and Neuro-Humoral Abnormalities of Young Normotensive Women at High Familial Risk for Hypertension. Hypertension Research; 33(8): 836-843.

Esmaeili M, Bijheh N, GHahramani Moghadam M. (2018). Effect of Combined (aerobic-resistance) Training on Aerobic Fitness, Muscle Strength, Blood Glucose, Insulin Resistance, and Serum Beta-Endorphin Levels in Type 2 Diabetic Women. IJOGI; 21(6): 34-46. [Full Text in Persian].

Fisher G, Brown AW, Bohan Brown MM, Alcorn A, Noles C, Winwood L and et al. (2015). High Intensity Interval- vs Moderate Intensity-Training for Improving Cardiometabolic Health in Overweight or Obese Males: A Randomized Controlled Trial. PLOS One; 10:1–15.

Ghafari M, Banitalebi E, Heidari A. (2017). Impact of High-Intensity Interval Training and at Concurrent Strength-Endurance Training on the Levels of Some Adipokines Associated with Insulin Resistance in Women with Diabetes Mellitus. Health Research Journal; 2(3):193-206.

Ivy JL. (1997). Role of Exercise Training in the Prevention and Treatment of Insulin Resistance and non-Insulin-Dependent Diabetes Mellitus. Sports medicine; 24(5):321-336.

José GN, Barbara M.M. A, Eduardo Z.C, Jhennyfer R, Gustavo D.F, José C.RN and et al. (2016). Impact of Long-Term High-Intensity Interval and Moderate Intensity Continuous Training on Subclinical Inflammation in Overweight/Obese Adults. Journal of Exercise Rehabilitation; 12(6):575-580.

José Gerosa-Neto, Barbara M.M. Antunes, Eduardo Z. Campos, Jhennyfer Rodrigues and et all. (2016). Impact of long-term high-intensity interval and moderate intensity continuous training on subclinical inflammation in overweight/obese adults. Journal of Exercise Rehabilitation; 12(6):575-580.

Jackson J. Fyfe, David J. Bishop, Evelyn Zacharewicz, Aaron P. Russell and et all. (2016). Concurrent exercise incorporating high-intensity interval or continuous training modulates mTORC1 signaling and microRNA expression in human skeletal muscle. J Physiol Regul Integr Comp Physiol; 310(11):R1297-311.

Jackson AS, Pollock ML. (1978). Generalized Equations for Predicting Body Density of Men. British Journal of Nutrition; 40(3): 497-504.

Khammassi M, Ouerghi N, Hadj-Taieb S, Feki M, Thivel D, Bouassida A. (2018). Impact of a 12-Week High-Intensity Interval Training without Caloric Restriction on Body Composition and Lipid Profile in Sedentary Healthy Overweight/Obese Youth. Journal of Exercise Rehabilitation; 14(1):118-125.

Kessler H. S, Sisson S. B, and Short K. R. (2012). "The Potential for High-Intensity Interval Training to Reduce Cardiometabolic Disease risk." Sports medicine; 42(6):489-509.

Keating S.E, Machan E. A, Connor H.T.O, Gerofi J. A, Sainsbury A, Caterson I.D, Johnson N.A. (2014). Clinical Study Continuous Exercise but Not High Intensity Interval Training Improves Fat Distribution in Overweight Adults. Journal of Obesity; 25–36.

Kannan U, Vasudevan K, Balasubramaniam K, Yerrabelli D, Shanmugavel K, John NA. (2014). Effect of Exercise Intensity on Lipid Profile in Sedentary Obese Adults. Journal of Clinical & Diagnostic Research; 8(7):BC08-10.

Leggate M, Carter WG, Evans MJ, Vennard RA, Sribala-Sundaram S, Nimmo MA. (2012). Determination of inflammatory and prominent proteomic changes in plasma and adipose tissue after high-intensity intermittent training in overweight and obese males. Journal of Applied Physiology; 112(8): 1353–1360.

Lee S, Bacha F, Hannon T, Kuk JL, Boesch C, Arslanian S. (2012). Effects of Aerobic Versus Resistance Exercise without Caloric Restriction on Abdominal Fat, Intrahepatic Lipid, and Insulin Sensitivity in Obese Adolescent Boys: A Randomized, Controlled Trial. Diabetes; 61(11):2787– 95.

Little JP, Gillen JB, Percival ME, Adeel S, Mark A.T, Zubin P and et al. (2011). Low-Volume High Intensity Interval Training Reduces Hyperglycemia and Increases Muscle Mitochondrial Capacity in Patients with Type 2 Diabetes. Journal of Applied Physiology; 111:1554–1560.

Malmivara S. (2015). The Effect of High-Intensity Interval Exercise Program on Blood Lipids and Hormones in Recreationally Active Adults. [Master’s Dissertation]. Exercise Physiology. Department of Biology of Physical Activity University of Jyväskylä.

McCormack SE, McCarthy MA, Harrington SG, Farilla L, Hrovat MI, Systrom DM and et al. (2014). Effects of Exercise and Lifestyle Modification on Fitness, Insulin Resistance, Skeletal Muscle Oxidative Phosphorylation and Intramyocellular Lipid Content in Obese Children and Adolescents. Pediatr Obes; 9(4): 281-91.

Ogden CL, Carroll MD, Kit BK, Flegal KM. (2014). Prevalence of Childhood and Adult Obesity in the United States, 2011-2012. JAMA; 311: 806–814.

Ouerghi N, Ben Fradj M K, Bezrati I, Feki M, Kaabachi N, Bouassida A. (2017). Effect of High-Intensity Interval Training on Plasma Omentin-1 Concentration in Overweight/Obese and Normal-Weight Youth. Obes Facts; 10:323–331.

Sheikholeslami Vatani D, Ebrahimi A. Effect of Moderate Continuous Training vs. (2018). High-Intensity Interval Training on Visceral and Subcutaneous Fats in Obese Women. Journal of Rafsanjan University of Medical Sciences; 16:999-1012. [Full Text in Persian].

Sarmadian M, Khorshidi D. (2016). Effect of Combined Training on Body Composition, Lipids and Metabolic Syndrome Index in Obese and Overweight Menopausal Women. JOGE; 1(2): 36-44. [Full Text in Persian].

Shabani R, Jalali Z, Nazari M. (2018). Effects of Concurrent Strength and Aerobic Training on Blood Glucose Homeostasis and Lipid Profile in Females with Overweight and Obesity. Zahedan Journal Research Medical Sciences; 20(4):e13746. [Full Text in Persian].

Simbo SY. (2013). Effects of Exercise and Diet-Induced Weight Loss in Overweight/Obese Women on Characterization of Serum/White Blood Cells, MicroRNAs and Cytokine Gene Transcription [Ph.D. Dissertation]. Texas: A&M University.

Sugiura H, Kajima K, Iwata H, Matsuoka T, Mirbod SM. (2002). Effects of Long Term Moderate Exercise and Increase in Number of Daily Steps on Serum Lipids in women: randomized controlled trial. BMC Women's Health; 2(1)3.

Schwingshackl L, Dias S, Strasser B, Hoffmann G. (2013). Impact of Different Training Modalities on Anthropometric and Metabolic Characteristics in Overweight/Obese Subjects: A Systematic Review and Network Meta-Analysis. PLOS One; 8(12). e82853.

Schwingshackl L, Missbach B, Dias S, Konig J, Hoffmann G. (2014). Impact of Different Training Modalities on Glycaemic Control and Blood Lipids in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis. Diabetologia; 57(9):1789–97.

Torabi S, Asadi MR, Tabrizi A. (2017). The Effect of 8 Weeks of Moderate-Intensity Endurance Training on Serum Levels of Liver Enzymes and Insulin Resistance Index in Women with Type 2 Diabetes. Qom University of Medical Sciences Journal; 11(7):47-55. [Full Text in Persian].

World health organization. Global Recommendations on Physical Activity for Health. (2010).

Weston KS, Wisloff U & Coombes JS. (2014). High-Intensity Interval Training in Patients with Lifestyle-Induced Cardiometabolic Disease: A Systematic Review and Metaanalysis. British Journal of Sports Medicine; 48: 1227-1234.

Zaer Ghodsi N, Zolfaghari MR, Fattah A. (2016). The Impact of High Intensity Interval Training On Lipid Profile, Inflammatory Markers and Anthropometric Parameters in Inactive Women. mljgoums; 10(1):56-60.

Zouhal H, Jacob C, Delamarche P, Gratas-Delamarche A. (2008). Catecholamines and the Effects of Exercise, Training and Gender. Sports Medicine; 38:401–423.