اثر جنسیت بر سطوح p53 متعاقب دویدن سراشیبی در غیرورزشکاران

نوع مقاله : مقاله پژوهشی

نویسندگان

1 استادیار، گروه تربیت بدنی و علوم ورزشی، واحد مریوان، دانشگاه آزاد اسلامی ، مریوان، ایران

2 کارشناسی ارشد فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، واحد مریوان، دانشگاه آزاد اسلامی ، مریوان، ایران

10.22049/jassp.2019.26615.1260

چکیده

هدف: اثر جنسیت بر آپوپتوزش ناشی از فعالیت ورزشی مشخص نیست. هدف از این مطالعه بررسی اثر جنسیت بر سطوح p53، بعنوان شاخص آپوپتوزیس، بعد از دویدن سراشیبی در غیر ورزشکاران بود. روش­شناسی:18نفر با دامنه سنی بین 18 تا 30 سال به به صورت تصادفی به عنوان آزمودنی انتخاب و به دوگروه 9 نفره (9 نفر مرد و 9 نفر زن) تقسیم شدند. آزمودنی­ها 40 دقیقه دویدن سراشیبی (12% شیب) با شدت70 درصد ضربان قلب بیشینه را انجام دادند و نمونه های خونی قبل و بلافاصله پس از فعالیت گرفته شد. نمونه های خونی جهت تعیین سطح سرمی p53 ارزیابی شد. یافته­ ها: نتایج نشان داد که p53 بعد از دویدن سراشیبی نسبت به قبل فعالیت در هر دو گروه مرد و زن بطور معناداری افزایش داشت اما مقدار این افزایش در بین دو گروه مردان و زنان تفاوت معناداری نداشت. نتیجه ­گیری: اگرچه نیاز به مطالعات بیشتری است، اما این پژوهش نشان داد که جنسیت نقش مهمی در واکنش آپوپتوزیس به دویدن سراشیبی در غیرورزشکاران ندارد.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of Gender on p53 Levels After Downhill Running in Non-Athletes

نویسندگان [English]

  • Hassan Faraji 1
  • Fatemeh Rostami 2
1 Assistant Professor, Department of Physical Education, Marivan branch, Islamic Azad University, Marivan, Iran
2 MSc of Exercise Physiology, Department of Physical Education, Marivan branch, Islamic Azad University, Marivan, Iran
چکیده [English]

Aim: The effect of gender on related-exercise apoptosis is unclear. The aim of this study was to investigate the effect of gender on the p53 level, as apoptosis marker, after downhill running in non-athletes. Methods: Eighteen individuals between the ages of 18 and 30 years were randomly selected and divided into 9 groups (9 males and 9 females). Subjects performed downhill running (12% incline) at 70% of HRmax for 40 min and blood samples were taken before exercise and immidatly after exercise. Blood samples were assayed for serum level of p53. Results:The results showed that p53 was significantly increased after running downhill compared to pre-test in both male and female groups, but this increase was not significantly different between the two groups of men and women. Conclusions: Although more research is needed, we showed that gender was not found to play an important role in apoptosis response to downhill running in non-athletes.

کلیدواژه‌ها [English]

  • Downhill running
  • p53
  • Apoptosis
  • Gender
 
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