اثر تمرین مقاومتی بر سطوح سرمی بیومارکرهای منتخب قلبی مردان سالمند دیابتی

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 استادیار گروه تربیت بدنی و علوم ورزشی، واحد بوئین زهرا، دانشگاه آزاد اسلامی، بوئین زهرا، ایران.

2 استاد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت، ایران.

3 استادیار گروه تربیت بدنی و علوم ورزشی، دانشگاه صنعتی امیر کبیر، تهران، ایران.

10.22049/jahssp.2022.27711.1449

چکیده

هدف: سن یک عامل خطر مهم برای دیابت نوع 2 و بیماری­های قلبی عروقی است. هدف از پژوهش حاضر، بررسی تأثیر تمرینات مقاومتی بر سطوح سرمی بیومارکرهای منتخب قلبی از جمله hs-CTnI و GDF-15 در مردان سالمند دیابتی می­باشد. روش شناسی: این تحقیق از نوع تجربی با طرح پیش آزمون - پس آزمون بود؛ بدین منظور 24 نفر به­ صورت انتخابی از بین مردان سالمند دیابتی (سن: 6/6±7/71 سال، وزن: 5/13±1/74 کیلوگرم، شاخص توده بدنی: 4/4±7/26 کیلوگرم بر مجذور متر) به عنوان آزمودنی­های تحقیق انتخاب و به صورت تصادفی در 2 گروه تمرین مقاومتی (12 نفر) و کنترل (12 نفر) تقسیم شدند. پروتکل تمرینی به ­مدت هشت هفته با سه جلسه در هفته، هشت حرکت و هر حرکت با 70 درصد یک تکرار بیشینه برای گروه تمرینی طراحی گردید. گروه کنترل نیز به ­منظور مقایسه با گروه تجربی و بررسی تأثیر زمان هشت هفته­ای خونگیری پیش­آزمون با پس­آزمون، در آسایشگاه سالمندان کهریزک بدون هیچ فعالیت ورزشی تحت نظر بودند. برای اندازه­گیری سطوح سرمی hs-CTnI و GDF-15 به­ ترتیب از روش کِمی لومینسانس و الایزای ساندویچی استفاده گردید. داده­ها با استفاده از نرم افزار SPSS نسخه 24 تحلیل گردید. یافته­ها: سطوح سرمی hs-CTnI پس از هشت هفته تمرینات مقاومتی کاهش معنی­داری داشت (001/0=P). در­ حالی­که سطوح سرمی GDF-15 تغییر معنی­داری نشان نداد (71/0=P). نتیجه­گیری: تمرینات مقاومتی منجر به بروز نتایج متفاوتی از بیومارکرهای قلبی در مردان سالمند دیابتی می­گردد. با این­حال، داده­های پژوهش تأیید می­کند که تمرین مقاومتی ممکن است عوامل خطرزای قلبی را در مردان سالمند دیابتی بهبود بخشد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of resistance training on serum levels of selected cardiac biomarkers of diabetic elderly men

نویسندگان [English]

  • Ebrahim Rangraz 1
  • Bahman Mirzaei 2
  • Hojat Hatami 1
  • Hadi Miri 3
1 Assistant Professor, Department of Physical Education and Sport Sciences, Buinzahra Branch, Islamic Azad University, Buinzahra, Iran
2 Professor, Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Rasht, Iran.
3 Assistant Professor, Department of Physical Education and Sport Sciences, Amirkabir University of Technology, Tehran, Iran.
چکیده [English]

Aim:   age is an  important risk factor for type 2 diabetes mellitus and cardiovascular diseases. The aim of the present study was to investigate the effect of resistance training on serum levels of selected cardiac biomarkers including hs-CTnI and GDF-15 in elderly diabetic men. Methods: This research was an experimental study with a pretest-posttest design. For this purpose, 24 people were selected from among diabetic elderly men (Age: 71.7±6.6 years, weight: 74.1±13.5 kg, body mass index: 26.7±4.4 kg/m2) as research subjects and randomly divided into 2 groups of resistance training (12 people) and control (12 people). The training protocol was designed for eight weeks with three sessions per week, eight movements and each movement with 70% of one maximum repetition for the training group. The control group was also monitored in Kahrizak nursing home without any exercise to compare with the experimental group and to evaluate the effect of eight-week pre-test and post-test blood sampling time. Chemiluminescence and sandwich ELISA were used to measure serum levels of hs-CTnI and GDF-15, respectively. Data was analyzed using SPSS version 24 software. Results: Serum hs-CTnI levels decreased significantly after eight weeks of resistance training (p=0.001). While, Serum GDF-15 levels did not show significant changes (p=0.71). Conclusions: Resistance training leads to different outcomes of cardiac biomarkers in elderly diabetic men. However, our data confirm that resistance training may improve cardiac risk factors in elderly diabetic men.

کلیدواژه‌ها [English]

  • Resistance Training
  • Troponin
  • Growth Differentiation Factor 15
  • aging
  • Type 2 Diabetes

Publisher: Azarbaijan Shahid Madani University          Copyright © The Authors   

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 10، شماره 1
فروردین 1402
صفحه 27-38

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  • تاریخ دریافت: 17 اسفند 1400
  • تاریخ بازنگری: 03 خرداد 1401
  • تاریخ پذیرش: 03 خرداد 1401

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