عنوان مقاله [English]
The aim of current study is investigation effectiveness of three months of aerobic exercise with Origanum majorana extract on male rats’ soleus muscle apoptosis. In current experimental study, 35 heads of male rats were alternated randomize in 5 groups (aerobic exercise, Origanum majorana extract, exercise+ Origanum majorana extract, 6 months controlling and also 3 months controlling. Exercise and exercise+ Origanum majorana extract groups implemented aerobic exercises during 12 weeks (5 days per week, 15% inclination, 10-60 minutes and 24-33 m/m speed). After 48 hours of last exercise, male rats’ soleus muscle was extracted and involved genes expression in apoptosis (Caspase 9 and Cythocrome C) were investigated by PCR. Data were analyzed by one-way variance analysis test at 0.05 significant levels. Results showed that, after intervention; soleus muscle weight and its proportion against body weight had significant difference (P<0.05) between groups. Also caspase 9 relative expression amount between groups had significant difference (P<0.05) after intervention, but there wasn't significant difference between groups according to Cythocrome C relative expression amount. (P>0.05) Aging cause to increasing rats body weight and reducing soleus muscle weight against body weight and also Caspase 9 increase simultaneously, but Cythocrome C expression amount doesn’t change. So, exercise and consumption of Origanum majorana extract lower mentioned increasing cases.