بررسی اثر 12 هفته تمرین تداومی با شدت Fatmax و آستانه بی هوازی و تمرین تناوبی شدید بر شاخص مقاومت به انسولین بیماران پیش دیابتی

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دکتری فیزیولوژی ورزشی دانشگاه گیلان ایران

2 استاد فیزیولوژی ورزشی دانشکده تربیت بدنی و علوم ورزشی دانشگاه گیلان.

3 استادیار فیزیولوژی ورزشی، پژوهشگاه تربیت بدنی و علوم ورزشی تهران

چکیده

زمینه و هدف: هدف از مطالعۀ حاضر بررسی اثر 12 هفته تمرین تداومی و تناوبی شدید بر شاخص مقاومت به انسولین بیماران پیش دیابتی بود.
روش کار: 32 بیمار پیش دیابتی در 4 گروه 8 نفری کنترل (CON)، گروه تمرین تناوبی (HIT)، گروه تمرین تداومی با شدت Fatmax (FAT) و شدت آستانه بی هوازی (IAT) قرار گرفتند. قبل و بعد از 12 هفته تمرین ورزشی گلوکز و انسولین خون آزمودنی ها در آزمایشگاه سنجش و از آزمون آماری ANOVA برای تجزیه و تحلیل داده ها استفاده شد.
یافته ها: نتایج نشان داد که میزان تاثیر تمرین ورزشی بر گلوکز خون و شاخص مقاومت به انسولین فقط در گروه HIT با گروه IAT معنی دار است. همچنین میزان تاثیر تمرین ورزشی بر انسولین خون بین گروه FAT و HIT با IAT معنی دار است.
نتیجه گیری: نتایج تحقیق نشان داد که شدت و نوع فعالیت ورزشی از عوامل تاثیر گذار بر بهبود شاخص مقاومت به انسولین در افراد پیش دیابتی است.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

The effect of 12 weeks of continuous training at Fatmax intensity and anaerobic threshold and high intensity interval training on insulin resistance index in Pre Diabetes Patient

نویسندگان [English]

  • seyed saleh safari mosavi 1
  • Hamid Mohebbi 2
  • Hadi Rohani 3
1 Department of Exercise Physiology, Faculty of Sport Science,University of Guilan, Iran.
2 Professor in Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Guilan, Rasht, Iran.
3 Assistant Professor in Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Science, Sport Science Research Institute, Tehran, Iran.
چکیده [English]

Background and Objective: the aim of this study was the effect of 12 weeks continuous and high intensity interval training on insulin resistance index in pre diabetes patient.
Materials and Methods: Thirty tow pre diabetes patients were divided into 4 groups of 8 people control (CON), high intensity interval training group (HIT), continuous training at Fatmax intensity group (FAT) and anaerobic threshold (IAT). Pre and post of exercise training for 12 weeks blood glucose and insulin was determined in laboratory and the ANOWA was used to analyze the variables.
results: results showed that the effect of exercise training on Blood glucose and insulin resistance index the difference was significantly in the HIT than in IAT groups. also, the effect of exercise training on Blood insulin in FAT, IAT, and HIT groups was 26%, 17% and 26% respectively, the difference was significantly in the FAT and HIT than in IAT groups.
Conclusion: Results showed that the intensity and type of exercise factors effective on insulin resistance index in pre diabetes patient.

کلیدواژه‌ها [English]

  • Blood glucose
  • Blood insulin
  • pre diabetes
  • continuous and high intensity interval training
 
 
1-      Tabak AG, Herder C, Rathmann W, Brunner EJ, Kivimaki M. Prediabetes: a high-risk state for diabetes development. Lancet. 2012; 379: 2279–2290.
2-      Earnest CP. Exercise interval training: an improved stimulus for improving the physiology of pre-diabetes. Med Hypotheses. 2008; 71:752-761.
3-      American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2011; 34: S62–69.
4-      Gerstein HC, Santaguida P, Raina P, et al. Annual incidence and relative risk of diabetes in people with various categories of dysglycemia: a systematic overview and meta-analysis of prospective studies. Diabetes Res Clin Pract 2007; 78: 305–312.
5-      Li G, Zhang P, Wang J. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing diabetes prevention study: a 20-year follow-up study. Lancet. 2008; 371:1783–1789.
6-      Hordern MD, Dunstan DW, Prins JB, Baker MK, Singh MA, Coombes JS. Exercise prescription for patients with type 2 diabetes and pre-diabetes: a position statement from Exercise and Sport Science Australia. J Sci Med Sport. 2012; 15:25-31.
7-      Venables M, Jeukendrup A. Endurance training and obesity: effect on substrate metabolism and insulin sensitivity. Med Sci Sports Exer. 2008; 40:495–502.
8-      Hordern  MD,  Coombes  JS,  Cooney  LM,  et  al.  Effects  of  exercise  intervention  on  myocardial  function  in  type  2  diabetes.  Heart 2009; 95:1343–1349.
9-      Achten J, Venables MC, Jeukendrup AE. Fat oxidation rates are higher during running compared with cycling over a wide range of intensities. Metabolism. 2003; 52: 747–752.
10-    Ben Ounis O, Elloumi M, Amri M, Zbidi A, Tabka, Z, Lac G. Impact of diet, exercise and diet combined with exercise programs on plasma lipoprotein and adiponectin levels in  obese  girls. J of Sport Sci and Med. 2008; 7: 437-445.
11-    Mayer-Davis EJ, E’Agostino R, Karter AJ, Haffner SM, Rewers MJ, Saad M, Bergman RN. Intensity, and amount of physical activity in relation  to  insulin  sensitivity:  the  Insulin  Resistance  Atherosclerosis Study. JAMA 1998; 279: 669–674.
12-    Mohebbi H, Nourshahi M, Ghasemikaram M, Safarimosavi S. Effects of exercise at individual anaerobic threshold and maximal fat oxidation intensities on plasma levels of nesfatin-1 and metabolic health biomarkers. J Physiol Biochem. 2015; 71:79-88.
13-    Boule NG, Haddad E, Kenny GP, et al. Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. JAMA 2001; 286:1218–1227.
14-    Oliveira BR, Slama FA, Deslandes AC, Furtado ES, Santos TM. Continuous and high-intensity interval training: which promotes higher pleasure?. PLoS One. 2013; 268: 782-95.
15-    Larsen S, Danielsen JH, Søndergård SD, Søgaard D, Vigelsoe A, Dybboe R, Skaaby S, Dela F, Helge JW. The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. Scand J Med Sci Sports. 2015; 25: 59-69.
16-    Little JP, Gillen JB, Percival ME, Safdar A, Tarnopolsky MA, Punthakee Z, Jung ME, Gibala MJ. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. J Appl Physiol. 2011; 111:1554-1560.
17-    Riddell MC, Jamnik VK, Iscoe KE, Timmons BW, and Gledhill N. Fat oxidation rate and the exercise intensity that elicits maximal fat oxidation decreases with pubertal status in young male subjects. J Appl Physiol. 2008; 105: 742–748.
18-    Jeukendrup AE and Wallis GA. Measurement of substrate oxidation during exercise by means of gas exchange measurements. Int J Sports Med. 2005; 26:S28–37.
19-    Martin JG, Jonathan PL, Maureen JM, John AH. Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol. 2012; pp:1077–1084
20-    Ferrannini E, Gastaldelli A, Iozzo P. Pathophysiology of prediabetes. Med Clin North Am 2011; 95: 327–339.
21-    Tabák AG, Jokela M, Akbaraly TN, Brunner EJ, Kivimäki M, Witte DR. Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study. Lancet 2009; 373: 2215–2221.
22-    Haskell WL, Lee IM, Pate RR, et al. Physical activity and Public Health:   updated recommendation for Adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 2007; 39: 1423–1434.
23-    Hansen D, Dendale P, Jonkers RA, et al. Continuous low- to moderate intensity exercise training is as effective as moderate- to high-intensity exercise training at lowering blood hba(1c) in obese type 2 diabetes patients. Diabetologia 2009.
24-    Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, et al. PGC1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003; 34: 267–273.
25-    Earnest CP. Exercise interval training: an improved stimulus for improving the physiology of pre-diabetes. Med Hypotheses 2008; 71:752-761.
26-    Ahmadizad S., Haghighi A.H., Hamedinia M.R. (2007). Effects of resistance versus endurance training on serum adiponectin and insulin resistance index. Eur J Endocrinol; 157  625-631.
27-    Houmard JA, Tanner CJ, Slentz CA, Duscha BD, McCartney JS, Kraus WE. (2004). Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol; 96:101–116
28-    Mohebbi H, Mighadasi M, Rahmaninia F, Hassannia S. Effect of 12 weeks high intensity aerobic training and a week detraining on plasma adiponectin, insulin resistance and central and peripheral fat volume in obese middle aged men. Olampic. 2010; 18: 33-46.
29-    Bruce CR, Kriketos AD, Cooney GJ, Hawley JA. Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with type 2 diabetes. Diabetologia 2004; 47:23–30.