تاثیر تمرین ترکیبی بر تغییرات غلظت و همبستگی نوروتروفین مشتق مغزی و آیریزین سرمی

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دکتری فیزیولوژی ورزشی از دانشگاه شهید چمران اهواز

2 کارشناس ارشد فیزیولوژی ورزشی، مجتمع آموزش عالی سراوان

10.22049/jassp.2019.26523.1198

چکیده

چکیده
زمینه و هدف: نوروتروفین مشتق مغزی نه تنها در سیستم عصبی، بلکه با فرایند‌های مولکولی مرکزی و محیطی متابولیسم انرژی و هموستاز مرتبط است. آیریزین نیز، میوکین تازه شناسایی شده است که از عضلات اسکلتی ترشح می‌شود و ارتباط مهمی بین فعالیت بدنی و سلامتی دارد.
مواد و روش‌‌ها: نمونه آماری تحقیق 20 نفر مرد دارای اضافه وزن می‌باشند که بصورت تصادفی انتخاب و به دو گروه کنترل و تجربی تقسیم شدند. نمونه‌گیری‌های خونی در دو مرحله، قبل از شروع فعالیت و نمونه‌گیری دوم، 48 ساعت بعد از اتمام دوره تمرینی گرفته شد.
یافته‌ها: سطوح آیریزین پس از دوره تمرین ترکیبی نسبت به قبل از فعالیت، افزایش معنی‌داری داشت. همچنین غلظت BDNF نیز، بعد از دوره تمرینی نسبت به قبل از فعالیت، بطور معنی‌داری افزایش داشت. ولی با این وجود، همبستگی معنی‌داری بین مقادیر غلظت آیریزین و BDNF آزمودنی‌ها مشاهده نشد.
نتیجه‌گیری: آیریزین می‌تواند سبب تغییرات متابولیکی و فیزیولوژیکی داخل بدن شود و نقش محافظتی در برابر وضعیت‌های مرتبط با بی‌تحرکی نظیر چاقی داشته باشد. BDNF نیز در نتیجه فعالیت بدنی افزایش می‌یابد و علاوه بر نقش حیاتی در تمایز نرونی و سلامت مغزی، نقش متابوتروپیکی دارد که نقش کلیدی از طریق مسیر هیپوتالاموس در کنترل وزن و هموستاز انرژی ایفا می‌کند.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Investigating The Changes of Irisin and Brain-derived neurotrophic factor Levels due to The Combined Training

نویسندگان [English]

  • Yazgaldi Nazari 1
  • Araz Nazari 2
1 Ph.D in Exercise Physiology, Shahid Chamran University, Iran.
2 Department of Physical Education and Sport sciences, Higher Educational Complex of Saravan, Iran.
چکیده [English]

Abstract
Background and Objectives: brain derived neurotrophic factor not only important in the nervous system, but also in central and peripheral molecular processes that related to energy metabolism and homeostasis. Also irisin, a novel myokine that is secreted from skeletal muscles, has an important relationship between physical activity and health.
Materials & Methods: In this study, 20 overweight men that were randomly selected and equally divided into control and experimental groups. Blood samples were taken two times, before the start of training, and final samples, 48 hours after the end of the eight-week training.
Results: Serum Irisin levels, after the completion of combined training than pre training significantly increased. Also, BDNF levels in the training group, after acute and chronic exercise training significantly increased. But significant correlation between the concentrations of Irisin and BDNF levels of the subjects was not observed.
Conclusion: Serum irisin and brain-derived neurotrophic factor levels, influenced by physical activity. Irisin can cause metabolic and physiological changes within the body and play a protective role against conditions such as obesity that associated with inactivity. Likewise, brain-derived neurotrophic factor increased as a result of physical activity and also the critical role in the differentiation of neurons and mental health, do a key role in controlling body weight and energy homeostasis.

کلیدواژه‌ها [English]

  • Combined training
  • Irisin
  • Myokine
  • Brain-derived neurotrophic factor
  • Overweigh
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