نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I
نویسندگان
1 گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران.
2 گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Background& purpose: Fibroblast growth factors (FGFs) constitute a large family of growth factors that act on different receptors (FGFRs), resulting in diversity and redundancy in biological responses. The aim of the present study was to compare the effects of eight weeks of high-intensity resistance, endurance, and interval training on the expression of fibroblast growth factor-1 (FGF-1) and its receptor (FGFR-1) in adipose tissue of obese male rats. Methods: Twenty-four male Wistar rats with an average age of 10 weeks and a weight of 150 to 250 grams were purchased. After six weeks of high-fat diet, and after matching based on body weight, the rats were divided into four groups of six including control, high-intensity interval training, resistance and endurance training. They trained five sessions per week for eight weeks. Real Time-PCR was used to measure FGF-1 and FGFR-1 gene expression. One-way analysis of variance and Tukey's post hoc test were used to determine the difference between groups at a significance level of p<0.05. Results: FGF-1 gene expression increased significantly in the high-intensity interval training and resistance training groups compared to the control group. However, this increase was not significant in the endurance training group. Also, the expression of this gene showed a significant increase in the high-intensity interval training and resistance training groups compared to the endurance group. FGFR-1 gene expression increased significantly in the high-intensity interval training and resistance training groups compared to the control group. However, this increase was not significant in the endurance training group. Also, no difference in the increase in gene expression was observed between the training groups.Conclusions: The hypothesis of the influence of the FGF-1 and FGFR-1 signaling pathway on the control of glucose metabolism seems plausible.
کلیدواژهها [English]
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