نوع مقاله : مقاله مروری Released under (CC BY-NC 4.0) license I Open Access I
نویسندگان
1 کارشناسی ارشد فیزیولوژی ورزش، گروه تربیت بدنی و علوم ورزشی، دانشگاه یاسوج، یاسوج، ایران.
2 گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی دانشگاه فردوسی مشهد، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Background: Overweight and obesity are related to many diseases. Leptin and acylated ghrelin hormones play a role in regulating energy balance. Physical activity can improve leptin and acylated ghrelin in humans. The aim of the present study was the effect of aerobic exercise on leptin and acylated ghrelin in overweight and obese people.
Methods: A systematic search of English and Farsi articles published in PubMed, Web of Science, Scopus, Sid and Magiran databases was conducted until January 2024. The present meta-analysis was conducted to investigate the effect of aerobic exercise on leptin and acylated ghrelin in overweight and obese people. Mean difference and 95% confidence interval (CI) were calculated using random effect model. Heterogeneity was evaluated using the (I2) test, and publication bias was evaluated by visual analysis of the funnel plot and Egger's test..
Findings: In total, 33 studies on 1157 overweight and obese subjects, which were meta-analyzed, the results showed that aerobic exercise in overweight and obese subjects caused a significant decrease in leptin with the mean weight difference of -0.33 mg/dL (p=0.001) and the significant increase of acylated ghrelin was compared to the control group by the weighted mean difference of 0.48 mg/dL (p=0.002).
Conclusions: The results showed that aerobic exercises with a significant effect on reducing leptin and increasing acylated ghrelin can be a suitable and efficient method to regulate appetite in overweight and obese people.
کلیدواژهها [English]