نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I
نویسندگان
1 گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی و تندرستی، پردیس بین المللی دانشگاه تهران، تهران، ایران
2 دانشیار ، گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی دانشگاه تهران، دانشگاه تهران، ایران
3 دانشیار، گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی دانشگاه تهران، دانشگاه تهران، ایران
4 استاد، گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی دانشگاه تهران، دانشگاه تهران، ایران
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Introduction and Objective: Muscle damage occurs in not only pathological conditions (muscular dystrophy) but also physiological challenging due to eccentric exercises and causes muscle dysfunction, inflammation of muscle fibers and muscle pain. New blood biomarkers to assess exercise-induced muscle damage have attracted the attention of many researchers. The aim of this study was to determine the changes in circulating myomesin 3 fragments as a new biomarker for exercise induced muscle injury Methodology: 36 inactive women were selected and randomly assigned to three groups of eccentric exercise, concentric exercise and control. After a familiarization period, while the eccentric exercise group performed one session of running on a treadmill with negative slope (negative slope of 10 degrees, at 60% VO2max and for 30 minutes) and concentric exercise group performed one session of running on a treadmill with positive slope (positive slope of 10 degrees, at 60% VO2max and for 30 minutes), the control group had no exercise. 48 hours before and after exercise, blood sampling was taken to evaluate the effects of training response Results: one session of running at a negative and positive slope significantly increased serum levels of myomesin 3 and creatine kinase compared to the control group(p≤0.001,p≤021 respectively). The increase in the levels of myomesin 3 and creatine kinase in the negative slope exercise group was more than the positive inclination exercises, but this difference was not significant.
Conclusion: One session of eccentric exercise can increase serum levels of myomesin 3 in comparison with the concentric group. It seems that myomesin 3 can be confirmed as a new biomarker of muscle injury after exercise.
کلیدواژه‌ها [English]
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