نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I
نویسندگان
1 گروه تربیت بدنی و علوم ورزشی، دانشکده علوم انسانی، دانشگاه کاشان، کاشان، ایران
2 گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه کاشان، کاشان، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
The aim of the meta-analysis is to investigate the effect of exercise training on blood circulating levels of BDNF and IGF-1 in children and adolescents. Method. A comprehensive search was conducted in PubMed, Web of Science, Scopus, and Google Scholar databases, as well as Iranian databases from the inception to December 6, 2023. The inclusion criteria for this study based on the PICOS guidelines (population, intervention, comparison, variable and type of study) include: 1) children and adolescents 2) exercise training with an intervention duration of more than 2 weeks, 3) studies with a control group or measurement values in the pre-test; 4) BDNF, IGF-1 measured in blood circulation (serum and plasma) and 5) single group studies (without control group) and two group studies (with control group). To determine the effect size, SMD and 95% confidence intervals (CIs) were calculated using the random model. Results. A total of 21 studies including 855 children and adolescent individuals with an average age of 7 to 17 years were included in the meta-analysis. Based on meta-analysis results, exercise training leads to a significant increase in BDNF levels with medium effect size [SMD = 0.51, (Cl: 0.91 to 0.11), P=0.01]. Nevertheless, exercise training did not have a significant effect on IGF-1 levels [SMD = 0.25 (Cl: 0.61 to -0.11), P=0.17]. Conclusion. Exercise training may lead to beneficial effects in improving cognitive function and metabolic status of children and adolescents by increasing BDNF. However, exercise training did not have significant effects on IGF-1, and further studies is still needed to determine the role of exercise training.
کلیدواژهها [English]
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