تاثیر هشت هفته تمرین استقامتی و مصرف آلکالاین بر بیومارکرهای التهابی و استرس اکسیداتیوی در مردان چاق با سندرم متابولیک

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسنده

استادیار فیزیولوژی ورزش، گروه علوم ورزشی، دانشگاه اردکان، اردکان، ایران.

چکیده

هدف: امروزه مداخله تمرینات بدنی همراه با تغذیه ورزشی به عنوان یک روش درمانی موثر در تعدیل پاسخ­های التهابی و اکسایشی در افراد چاق مبتلا به سندرم متابولیک مطرح است. از این رو، هدف تحقیق حاضر بررسی تاثیر هشت هفته تمرین استقامتی و مصرف آلکالاین بر اینترلوکین-6 (6IL-)، فاکتور نکروز تومور-آلفا (TNF-α)، اکسید نیتریک (NO) و تیول­ تام (T-SH) در مردان چاق مبتلا به سندرم متابولیک بود. روش شناسی: تحقیق حاضر از نوع نیمه تجربی یک سوکور بود. بدین منظور 56 مرد (میانگین سنی 11/3±27/33 سال، میانگین وزنی 91/2±16/94 کیلوگرم و میانگین شاخص توده بدنی 32/1±56/32 کیلوگرم بر مترمربع) داوطلبانه در این تحقیق شرکت کردند. آزمودنی­ها به طور تصادفی به چهار گروه: تمرین استقامتی، تمرین استقامتی با آلکالاین، آلکالاین و کنترل تقسیم شدند. مداخله تمرینـی سه جلسه در هفته به مدت هشت هفته اجرا شد. آلکالاین (5/9pH ) به میزان kg/mL 10پس از هر جلسه تمرین دریافت شد. نمونه­های خونی  قبل از تمرین و 48 ساعت بعد از آخرین جلسه تمرین به منظور سنجش بیومارکرهای التهابی و استرس اکسیداتیو گرفته شد. یافته‌ها: نتایج نشان داد که مقادیر 6IL-، TNF-α در گروه­ تمرین استقامتی همراه با آلکالاین و تمرین استقامتی نسبت به گروه­های آلکالاین و کنترل کاهش معنادار و مقادیر NO و T-SH افزایش معنادار داشتند (05/0>p). بیشترین درصد تغییرات معنادار در مقادیر 6IL-،  TNF-α، NO و T-SH به گروه تمرین همراه با آلکالاین اختصاص داشت. مصرف هشت هفته آلکالاین به تنهایی باعث تغییرات معنا‌دار نشد (05/0<p). نتیجه‌گیری: اثر توام تمرین استقامتی و آلکالاین موجب بهبود بیشتر پاسخ­های التهابی و استرس اکسیداتیوی در مردان چاق با سندرم متابولیک می­شود.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of eight weeks of endurance training and alkaline consumption on inflammatory biomarkers and oxidative stress in obese men with metabolic syndrome

نویسنده [English]

  • حسن naghizadeh
Assistant Professor of exercise physiology, Department of Sport Sciences, Ardakan University, P.O. Box 184, Ardakan, Irann.
چکیده [English]

Aim: Nowadays, the intervention of physical exercises along with sports nutrition is considered as an effective treatment method in modulating inflammatory and oxidative responses in obese people with metabolic syndrome. Therefore, the aim of this research is to investigate the effect of eight weeks of endurance training and alkaline consumption on interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), nitric oxide (NO) and total thiol (T-SH) in Obese men with metabolic syndrome. Methods:  The current research was a semi-experimental one-blind type. For this purpose, 56 men (average age= 33.27±3.11 years, average weight= 94.16±2.91 kg and BMI= 32.56±1.32 kg/m2) voluntarily participated in this research.  Subjects were randomly divided into four groups: endurance training, endurance training with alkaline water, alkaline water and control. The training intervention was implemented three sessions a week for eight weeks. Alkaline water (pH 9.5) was received at the rate of 10 kg/mL after each training session. Blood samples were taken before training and 48 hours after the last training session to measure inflammatory biomarkers and oxidative stress. Results:  The results showed that the values of IL-6 and TNF-α in the group of endurance training with alkaline water and endurance training compared to the groups of alkaline water and control had a significant decrease, and the values of NO and T-SH had a significant increase (p<0.05). The highest percentage of significant changes in the values of IL-6, TNF-α, NO and T-SH were assigned to the training group with alkaline water. Alkaline water alone did not cause significant changes (P>0.05). Conclusions: Therefore, the combined effect of endurance exercise and alkaline water improves inflammatory responses and oxidative stress in obese men with metabolic syndrome.

کلیدواژه‌ها [English]

  • Endurance training
  • Alkaline
  • Inflammation
  • Oxidative stress
  • Metabolic syndrome

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 12، شماره 1
فروردین 1404
صفحه 66-80

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سابقه مقاله

  • تاریخ دریافت: 20 اسفند 1402
  • تاریخ بازنگری: 01 تیر 1403
  • تاریخ پذیرش: 02 تیر 1403

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