تاثیر تمرینات تناوبی با شدت بالا و تداومی با شدت متوسط بر مقادیر پروتئینی CTRP-3 چربی احشایی در رت های تغذیه شده با رژیم غذایی پرچرب

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه کاشان، کاشان، ایران

2 گروه فیزیولوژی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

چکیده

هدف: هدف مطالعه حاضر بررسی تاثیر تمرینات تناوبی با شدت بالا و تداومی با شدت متوسط بر مقادیر پروتئینی CTRP-3 چربی احشایی در رت­های تغذیه ‌شده با رژیم غذایی پرچرب می­باشد. روش پژوهش: 24 سر رت نر، نژاد ویستار، به طور تصادفی به چهار گروه رژیم غذایی استاندارد (ND) (6 سر)، رژیم غذایی پرچرب (HFD) (6 سر)، رژیم غذایی پرچرب با تمرین تناوبی با شدت بالا (HFD+HIIT) (6 سر)، رژیم غذایی پرچرب با تمرین تداومی با شدت متوسط (HFD+MICT) (6 سر)، تقسیم شدند. گروه های HIIT و MICT به مدت 8 هفته، 5 جلسه در هفته، به فعالیت ورزشی مختص گروه خود پرداختند. مقادیر پروتئینی CTRP-3 با استفاده از روش وسترن بلات اندازه گیری شد. داده­ها با استفاده از ازمون­های ANOVA و توکی تجزیه و تحلیل شدند. یافته‌ها: یافته ها نشان دادند که رژیم غذایی پرچرب منجر به کاهش معنادار CTRP-3 چربی احشایی نسبت به گروه رژیم غذایی استاندارد شد (002/0=P). در مقابل هردو HIIT و MICT  منجر به افزایش معنادار CTRP-3 چربی احشایی نسبت به گروه رژیم غذایی پرچرب شد (029/0=P، 004/0=P). با این وجود، تفاوت معنی داری بین گروه های تمرینی وجود نداشت (05/0<P). نتیجه‌گیری: تمرینات تناوبی با شدت بالا و تداومی با شدت متوسط می توانند اثرات منفی القاء شده با رژیم غذایی پرچرب بر CTRP-3 را معکوس کنند که ممکن است به واسطه همین فرایند نقش مهمی در بهبود مقاومت به انسولین ایفا کنند.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 protein levels of visceral fat in rats fed a high-fat diet

نویسندگان [English]

  • Marzieh Faramarzi 1
  • Keyvan Sharifmoradi 1
  • Zahra Pezeshki 2
  • Mousa Khalafi 1
1 Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran
2 Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده [English]

Aim:      The purpose of the present study is to investigate the effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 training and visceral improvement in diets fed with a high-fat diet. Methods: Twenty-four male Wistar rats were randomly divided into four groups: standard diet (ND) (6), high-fat diet (HFD) (6), high-fat diet with high-intensity interval training (HFD+HIIT) (6), high-fat diet with moderate intensity continuous training (HFD+MICT) (6). The HIIT and MICT groups participated in sports activities specific to their group for 8 weeks, 5 sessions per week. CTRP-3 protein levels were measured using western blot method. The data were analyzed using ANOVA and Tukey's tests. Results: The findings showed that the high-fat diet led to a significant decrease in visceral fat CTRP-3 compared to the standard diet group (P=0.002). In contrast, both groups of HIIT and MICT training led to a significant increase in visceral fat CTRP-3 compared to the high-fat diet group (P=0.029, P=0.004). However, there was no significant difference between the training groups (P<0.05). Conclusions: High-intensity intermittent and moderate-intensity continuous training can reverse the negative effects induced by a high-fat diet on CTRP-3, which may play an important role in improving insulin resistance through this process.

کلیدواژه‌ها [English]

  • High-fat diet
  • Exercise training
  • Visceral fat
  • CTRP-3
  • Insulin resistance

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 11، شماره 2
مهر 1403
صفحه 93-105

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سابقه مقاله

  • تاریخ دریافت: 09 بهمن 1402
  • تاریخ بازنگری: 20 اردیبهشت 1403
  • تاریخ پذیرش: 21 اردیبهشت 1403

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