اثر مکمل‌یاری اُمگا 3 و ویتامین E بر شاخص‌های آسیب سلولی و کوفتگی عضلانی پس از فعالیت بی‌هوازی در مردان جوان غیرفعال

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه گیلان، گیلان، ایران.

2 گروه فیزیولوژی ورزش، دانشکده علوم ورزشی، دانشگاه گیلان، گیلان، ایران.

چکیده

هدف: مطالعات نشان داده است که مصرف اُمگا-3 و ویتامین E می‌تواند اثرات ضد التهابی و آنتی‌اکسیدانی داشته باشد و در شرایطی که آسیب و التهاب عضلانی متعاقب فعالیت‌های ورزشی رخ می‌دهد، استفاده از این مکمل‌ها پیشنهاد گردیده است. هدف این مطالعه، تعیین اثر مصرف کوتاه‌مدت مکمل­های اُمگا-3 و ویتامین E بر برخی شاخص‌های تجزیه کلاژن (هیدروکسی لیزین و هیدروکسی پرولین سرم) و کوفتگی عضلانی (لاکتات دهیدروژناز، کراتین کیناز) افراد جوان بی تمرین بود. روش شناسی: مطالعات نشان داده است که مصرف اُمگا-3 و ویتامین E می‌تواند اثرات ضد التهابی و آنتی‌اکسیدانی داشته باشد و در شرایطی که آسیب و التهاب عضلانی متعاقب فعالیت‌های ورزشی رخ می‌دهد، استفاده از این مکمل‌ها پیشنهاد گردیده است. هدف این مطالعه، تعیین اثر مصرف کوتاه‌مدت مکمل­های اُمگا-3 و ویتامین E بر برخی شاخص‌های تجزیه کلاژن (هیدروکسی لیزین و هیدروکسی پرولین سرم) و کوفتگی عضلانی (لاکتات دهیدروژناز، کراتین کیناز) افراد جوان بی تمرین بود. یافته­ها: نتایج نشان داد که در نوبت مکمل یاری، مقادیر لاکتات دهیدروژناز (033/0p=) و هیدروکسی پرولین (046/0p=) 48 ساعت پس از فعالیت بی هوازی در مقایسه با مقادیر پایه به‌طور معنی‌داری افزایش یافت. در مقادیر کراتین کیناز (083/0p=) و هیدروکسی لیزین (088/0p=) تغییر معنی‌داری مشاهده نشد. نتیجه گیری: با توجه به یافته‌ها به نظر می‌رسد که مصرف ترکیبی اُمگا 3 و ویتامین  E نتوانست نقش حفاظتی بر برخی شاخص های مربوط به آسیب غشای سلولی و کلاژنی داشته باشد، هرچند برای نتیجه‌گیری دقیق‌تر نیاز به مطالعات بیشتری است.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Effect of omega-3 and vitamin E supplementation on some indices of collagen breakdown, damage and muscle contusion after explosive activity in young non-active

نویسندگان [English]

  • hossein Asadbegi 1
  • javad mehrabani 2
  • abuzar jorbonian 2
1 MSc in Exercise Physiology, Department of exercise physiology, Faculty of sport science, University of Guilan, Guilan, Iran.
2 Department of exercise physiology, Faculty of sport science, University of Guilan, Guilan, Iran.
چکیده [English]

Aim:      Studies have shown that the consumption of omega-3 and vitamin E can have anti-inflammatory and antioxidant effects, and the use of these supplements is suggested in situations where muscle damage and inflammation occurs following exercise activities. The aim of this study was to determine the effect of short-term consumption of omega-3 and vitamin E supplements on some indices of collagen breakdown (hydroxylysine and serum hydroxyproline) and muscle damage (lactate dehydrogenase, creatine kinase) in untrained young people. Materials and methods:   Eight healthy and non-active men (age: 21.33±2.12 years, fat percentage: 19.02±4.46) were selected using statistical methods to determine the sample size. Subjects were randomly divided into two conditions of supplement and placebo. The research design was carried out in a blind way and the subjects did not know about the content of the supplement packages until the end of the research protocol. At the time of taking supplements, they took 3000 mg of omega-3 supplement in three meals daily (1000 mg each) and 400 IU of vitamin E supplement in one meal. Soft gels containing oral paraffin were consumed as a placebo. On the eighth day, for both conditions of the research, the subjects had a bout of intense anaerobic activity, including 8 sets of 12 repetitions of pair jumping on the box and 8 sets of 12 repetitions of landing from the 43 cm box with a one-minute rest between each set. Before supplementing and 24 and 48 hours after performing anaerobic activity, blood samples tests were taken from the subjects. Result:  The results showed that the values of lactate dehydrogenase (p=0.033) and hydroxyproline (p=0.046) increased significantly in 48 hours after anaerobic exercise compared to baseline. No significant change was observed in the values of creatine kinase (p=0.083) and hydroxylysine (p=0.088) variables. Conclusion: According to the findings, it seems that the combined consumption of omega-3 and vitamin E could not have a protective role on some indicators related to cell membrane and collagen damage, although more studies are needed for a more accurate conclusion.

کلیدواژه‌ها [English]

  • Lactate Dehydrogenase
  • Creatine Kinase
  • Hydroxyproline
  • Hydroxylysine

مراجع

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 11، شماره 2
مهر 1403
صفحه 44-53

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سابقه مقاله

  • تاریخ دریافت: 18 آذر 1402
  • تاریخ بازنگری: 12 بهمن 1402
  • تاریخ پذیرش: 20 بهمن 1402

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