The effect of Pilates and aerobic training on serum levels of sirtoin-1, plasminogen activator inhibitor-1 and insulin resistance index in women with type 2 diabetes

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Department of Physical Education, Isalmic Azad University, Bojnourd branch, Bojnourd, Iran

2 birjand university

3 bojnord

4 PhD Candidate in Sports Physiology - Islamic Azad University, Bojnord Branch

Abstract

Aim:      Diabetes causes a wide range of serious health problems in humans. Sirtoin-1 and plasminogen activator inhibitor-1 are proteins that can help reduce the complications of type 2 diabetes. The purpose of this study was to investigate the effect of eight weeks of pilates and aerobic exercises on serum levels of sirtuin-1 and plasminogen activator inhibitor-1 and insulin resistance index in women with type 2 diabetes. Methods:  In this semi-experimental research, 33 women with type 2 diabetes (mean age: 60.91±2.37 and mean BMI: 29.89±3.46) were selected based on available and targeted sampling and were Randomly, they were placed in three groups of 11 people: Aerobics, Pilates and Control. The Pilates group performed Pilates exercises with an intensity of 45-65% of the reserve heart rate, and the aerobic group performed running exercises and relaxation exercises with the same intensity for eight weeks and three sessions per week (24 sessions in total). Data analysis was performed using one-way analysis of variance and Tukey's post hoc test. Results:  The results of the present study showed a significant difference between the training groups and the control group in the dependent variables of the research, so that the levels of sirtuin-1 (p=0.001) in the training groups increased significantly and plasminogen activator inhibitor-1 (p=0.001) And insulin resistance (p=0.001) was significantly reduced in these groups. Conclusion:  Aerobic exercises and pilates can have a significant effect in helping those suffering from this disease with the significant effect of effective factors in improving the condition of diabetes.

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References

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History

  • Receive Date: 10 December 2023
  • Revise Date: 23 February 2024
  • Accept Date: 24 February 2024

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