تاثیر تمرینات پیلاتس و هوازی بر سطح سرمی سیرتوئین-1، مهارکننده فعال کننده پلاسمینوژن-1 و شاخص مقاومت به انسولین در زنان مبتلا به دیابت نوع دو

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 گروه تربیت بدنی و علوم ورزشی، دانشگاه آزاد واحد بجنورد، بجنورد، ایران

2 استادیار رفتار حرکتی، دانشگاه صنعتی بیرجند، بیرجند، ایران.

3 کارشناس ارشد فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران.

4 دانشجوی دکتری فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران.

چکیده

هدف: دیابت سبب بروز طیف گسترده‎ای از مشکلات جدی سلامتی در انسان می‌شود. سیرتوئین‌-1 و مهارکننده فعال کننده پلاسمینوژن-1 پروتئین‌هایی هستند که می‌توانند به کاهش عوارض بیماری دیابت نوع 2 کمک نمایند. هدف از پژوهش حاضر، بررسی تأثیر هشت هفته تمرینات پیلاتس و هوازی بر سطوح سرمی سیرتوئین-1 و مهارکننده فعال کننده پلاسمینوژن-1 و شاخص مقاومت به انسولین در زنان مبتلا به دیابت نوع دوم بود. روش شناسی: در این پژوهش نیمه‌تجربی، تعداد 33 نفر از زنان مبتلا به دیابت نوع دوم (میانگین سن: 37/2±91/60 سال و میانگین BMI: 46/3±89/29 کیلوگرم بر متر مربع) بر اساس نمونه‌گیری در دسترس و هدفمند انتخاب شدند و  به صورت تصادفی ساده، در سه گروه 11 نفری هوازی، پیلاتس و کنترل قرار گرفتند. گروه پیلاتس، حرکات رشته پیلاتس را با شدت 45 تا 65 درصد ضربان قلب ذخیره و گروه هوازی، تمرینات دویدن و حرکات نرمشی را با همان شدت، به مدت هشت هفته و سه جلسه در هفته (در مجموع 24 جلسه) انجام دادند. تجزیه و تحلیل داده‌ها با استفاده از آنالیز واریانس یکطرفه و آزمون تعقیبی توکی انجام شد. یافته­ها: نتایج پژوهش حاضر نشان دهنده تفاوت معنا‌دار گروه‌های تمرین با گروه کنترل در متغیرهای وابسته پژوهش بود  به طوری که سطوح سیرتوئین-1 (001/0=p) در گروه‌های تمرین افزایش معنا‌دار و مهارکننده فعال کننده پلاسمینوژن-1 (001/0=p)  و مقاومت به انسولین (001/0=p) در این گروه‌ها کاهش معنا‌داری داشت. نتیجه گیری: تمرینات هوازی و پیلاتس با تاثیر معنا‌دار عوامل موثر در بهبود شرایط بیماری دیابت، می تواند تأثیر بسزایی در کمک به مبتلایان به این بیماری داشته باشد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of Pilates and aerobic training on serum levels of sirtoin-1, plasminogen activator inhibitor-1 and insulin resistance index in women with type 2 diabetes

نویسندگان [English]

  • Sadegh Cheragh-Birjandi 1
  • ali kheyrandish 2
  • seyedeh sepide tara 3
  • seyedeh sahar sharifian 3
  • halimeh masoodi 3
  • sara Asghari 4
1 Department of Physical Education, Isalmic Azad University, Bojnourd branch, Bojnourd, Iran
2 Assistant Professor, Birjand University of Technology, Birjand, Iran.
3 Department of Physical Education and Sport Sciences, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
4 Ph.D Candidate, Department of Physical Education and Sport Sciences, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
چکیده [English]

Aim:      Diabetes causes a wide range of serious health problems in humans. Sirtoin-1 and plasminogen activator inhibitor-1 are proteins that can help reduce the complications of type 2 diabetes. The purpose of this study was to investigate the effect of eight weeks of pilates and aerobic exercises on serum levels of sirtuin-1 and plasminogen activator inhibitor-1 and insulin resistance index in women with type 2 diabetes. Methods:  In this semi-experimental research, 33 women with type 2 diabetes (mean age: 60.91±2.37 and mean BMI: 29.89±3.46) were selected based on available and targeted sampling and were Randomly, they were placed in three groups of 11 people: Aerobics, Pilates and Control. The Pilates group performed Pilates exercises with an intensity of 45-65% of the reserve heart rate, and the aerobic group performed running exercises and relaxation exercises with the same intensity for eight weeks and three sessions per week (24 sessions in total). Data analysis was performed using one-way analysis of variance and Tukey's post hoc test. Results:  The results of the present study showed a significant difference between the training groups and the control group in the dependent variables of the research, so that the levels of sirtuin-1 (p=0.001) in the training groups increased significantly and plasminogen activator inhibitor-1 (p=0.001) And insulin resistance (p=0.001) was significantly reduced in these groups. Conclusion:  Aerobic exercises and pilates can have a significant effect in helping those suffering from this disease with the significant effect of effective factors in improving the condition of diabetes.

کلیدواژه‌ها [English]

  • Pilates training
  • aerobic training
  • sirtoin-1
  • plasminogen activator inhibitor-1
  • insulin resistance

مراجع

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 11، شماره 2
مهر 1403
صفحه 1-11

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سابقه مقاله

  • تاریخ دریافت: 19 آذر 1402
  • تاریخ بازنگری: 04 اسفند 1402
  • تاریخ پذیرش: 05 اسفند 1402

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