تأثیر 12 هفته تمرین تناوبی شدید و مصرف کورکومین بر شاخص‌های گلایسمیک، آدیپونکتین و پروفایل لیپیدی در مردان چاق مبتلا به دیابت نوع دو با چربی خون بالا

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 استادیار گروه علوم ورزشی، دانشکده علوم انسانی و اجتماعی، دانشگاه اردکان، اردکان، ایران.

2 گروه تربیت بدنی و علوم ورزشی، دانشگاه فنی و حرفه ای، تهران، ایران

3 دکتری فیزیولوژی ورزش، گروه تربیت بدنی، واحد تبریز، دانشگاه آزاد اسلامی، تبریز، ایران

چکیده

هدف: تمرینات بدنی و مصرف گیاهان دارویی با خواص ضدالتهابی یکی از پرکاربردترین روش­ها برای کاهش عوارض دیابت نوع دو است. هدف از این پژوهش بررسی اثر تعاملی 12 هفته تمرین تناوبی شدید و مصرف کورکومین بر شاخص‌های گلایسمیک، آدیپونکتین و پروفایل لیپیدی در مردان چاق مبتلا به دیابت نوع دو با چربی خون بالا بود. روش شناسی: پژوهش حاضر از نوع نیمه تجربی دوسوکور بود. جامعه آماری شامل مردان مبتلا به دیابت نوع دو با میانگین سنی 05/2±76/38 سال و وزنی96/2±00/89 کیلوگرم بودند که تعداد 60 نفر در این پژوهش شرکت کردند. آزمودنی­ها به طور تصادفی در چهار گروه، تمرین تناوبی شدید، تمرین تناوبی شدید + مصرف کورکومین، کورکومین و کنترل-دارونما قرار گرفتند. مداخله تمرینـی سه جلسه در هفته و مصرف کورکومین روزانه 2100 میلی‌گرم در سه وعده 700 میلی‌گرمی به مدت 12 هفته اجرا شد. قبل و بعد از تمرین شاخص‌های ترکیب بدنی و بیوشیمیایی سنجش شدند. از تحلیل واریانس تک راهه، تحلیل واریانس عاملی (2×2) اندازه­گیری مکرر و آزمون تی همبسته برای تحلیل داده­ها استفاده شد. یافته‌ها: اثر تعاملی تمرین و کورکومین موجب افزایش معنی‌دار آدیپونکتین (010/0=P)؛ و کاهش معنی‌دار گلوکز (0001/0=P)، انسولین (021/0=P)، هموگلوبین گلیکوزیله (021/0=P)، مقاومت انسولینی (001/0=P)، (0001/0=P) TC، (001/0=P) TG، (002/0=P) LDL و (011/0=P) HDL شد. تمرین به تنهایی باعث تغییرات معنی‌دار در تمام متغیرهای بیوشیمیایی شد، ولی مصرف کورکومین به تنهایی باعث تغییرات معنی‌دار نشد (05/0<P). نتیجه‌گیری: بنابراین، 12 هفته تمرین تناوبی شدید با مصرف کورکومین، وضعیت گلایسمیک و نیمرخ لیپیدی را در مردان مبتلا به دیابت نوع دو با چربی خون بالا در مقایسه با اثر اصلی تمرین و کورکومین، بیشتر بهبود بخشید.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of 12 weeks of high-intensity interval training and curcumin consumption on glycemic index, adiponectin and lipid profile in obese men with type2 diabetes hyperlipidemia

نویسندگان [English]

  • Hasan Naghizadeh 1
  • Faeze Heydari 2
  • Gabrial Pouzesh Jadidi 3
1 Associate Professor, Department of Exercise Physiology, Faculty of Humanities and Social, Ardakan University, Ardakan, Iran.
2 Department of Physical Education and sport science, Technical and Vocational University (TVU), Tehran, Iran.
3 PhD of exercise physiology, Department of Physical Education, Tabriz branch, islamic azad university, tabriz, Iran.
چکیده [English]

Aim:   Physical exercises and the consumption of medicinal plants with anti-inflammatory properties are one of the most widely used methods to reduce the complications of type 2 diabetes. The aim of this study was to investigate the interactive effect of 12 weeks of high-intensity interval training and curcumin consumption on glycemic index, adiponectin and lipid profile in obese men with type2 diabetes hyperlipidemia. Methods: The current research was a double-blind semi-experimental type. The statistical population included men with type 2 diabetes (mean age 38.76±2.05 years and weight 89.00±2.96 kg), 60 people participated in this research. Subjects were randomly divided into four groups: high-intensity interval training, high-intensity interval training + curcumin, curcumin, and placebo-control. The training intervention was performed three times a week and the consumption daily of curcumin was 2100 mg in three servings of 700 mg, for 12 weeks. Body composition and biochemical indices were measured before and after exercise. One-way ANOVA, two-way factorial ANOVA for repeated measurements and paired samples t test were used to analyze the data. Results: Interactive effect of exercise and curcumin significantly increased adiponectin (p= 0.010), and significantly decreased glucose (p= 0.0001), insulin (p= 0.0001), HbA1c (p= 0.021), insulin resistance (p= 0.001), TC (p= 0.0001), TG (p= 0.001), LDL (p= 0.002) and HDL (p= 0.011). Exercise alone caused significant changes in all biochemical variables (p<0.05), but curcumin consumption alone did not cause significant changes (P>0.05). Conclusions: Therefore, high-intensity interval training with curcumin consumption more improved glycemic status and lipid profiles in hyperlipidemia type 2 diabetes men more than the main effect of training and curcumin.

کلیدواژه‌ها [English]

  • HIIT
  • Anti-inflammatory supplement
  • Insulin resistance
  • metabolic syndrome

Publisher: Azarbaijan Shahid Madani University          Copyright © The Authors   

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 10، شماره 1
فروردین 1402
صفحه 50-66

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  • تاریخ دریافت: 12 مهر 1401
  • تاریخ بازنگری: 24 آذر 1401
  • تاریخ پذیرش: 06 دی 1401

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