تأثیر تمرین مقاومتی توأم با مصرف اسپیرولینا بر مالون دی آلدهید و ظرفیت تام آنتی اکسیدانی در مردان دارای اضافه وزن و چاق

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 دانشجوی دکتری فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه بیرجند، بیرجند، ایران.

2 استاد فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه بیرجند، بیرجند، ایران.

3 گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه بیرجند، بیرجند، ایران

4 استاد بیوشیمی بالینی، گروه بیوشیمی بالینی، دانشکده پزشکی، مرکز تحقیقات بیماری‌های قلب و عروق، دانشگاه علوم پزشکی بیرجند، بیرجند، ایران.

چکیده

هدف: یکی از مشکلات حاد جامعه­ی بشری کنونی، فقر فعالیت بدنی، اضافه وزن و چاقی است. هدف از پژوهش پیش­رو، بررسی تأثیر 8 هفته تمرین مقاومتی به همراه مصرف اسپیرولینا بر ظرفیت ­تام ­آنتی اکسیدانی و مالون­ دی ­آلدهید در مردان دارای اضافه وزن و چاق بود. روش شناسی: در این پژوهش 44 مرد 30 تا 50 ساله، با شاخص توده­ی بدنی بیشتر از 25 کیلوگرم بر متر مربع، به طور هدفمند انتخاب و تصادفی به چهار گروه تمرین + اسپیرولینا، تمرین + دارونما، اسپیرولینا و دارونما تقسیم شدند. تمرینات مقاومتی در 12 ایستگاه، به مدت هشت هفته و هر هفته سه جلسه، در شدت­های خیلی سبک، سبک–متوسط و سنگین اجرا شد. گروه­های اسپیرولینا و دارونما، به ترتیب روزانه دو عدد قرص (mg 500) اسپیرولینا و دارونما مصرف ‌کردند. خونگیری قبل و بعد از هشت هفته، به دنبال ۱۲ ساعت ناشتایی شبانه انجام گرفت. یافته‌ها: در همه­ی گروه­ها به جز دارونما، مالون دی ­آلدهید به طور معناداری کاهش (00/0=P) و ظرفیت تام ­آنتی اکسیدانی افزایش یافت (00/0=P). همچنین، بین مقادیر مالون دی ­آلدهید و ظرفیت تام ­آنتی اکسیدانی، در گروه تمرین+اسپیرولینا با دیگر گروه­ها، اختلاف معناداری مشاهده شد (00/0=P). گروه تمرین+ دارونما و اسپیرولینا با دارونما، در مقادیر مالون ­دی ­آلدهید و ظرفیت تام ­آنتی اکسیدانی، تفاوت معناداری داشتند (00/0=P). گروه تمرین+دارونما و اسپیرولینا در مقادیر مذکور تفاوت معناداری نداشتند (95/0=P). نتیجه‌گیری: احتمالاً ترکیب تمرین مقاومتی و اسپیرولینا می‌تواند در تعادل پراکسیدانی و آنتی اکسیدانی در مردان دارای اضافه وزن و چاق اثر مثبتی داشته باشد و از فشارهای اکسایشی ناشی از ورزش و همچنین اضافه وزن و چاقی جلوگیری کند.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of resistance training combined with spirulina consumption on malondialdehyde and total antioxidant capacity in overweight and obese men

نویسندگان [English]

  • Mohammad Reza Izadmehr 1
  • Mehdi Mogharnasi 2
  • Marziyeh Saghebjoo 3
  • Asghar Zarban 4
1 PhD student in Exercise Physiology, Faculty of Sports Sciences, University of Birjand, Birjand, Iran.
2 Professor of Exercise Physiology, Faculty of Sports Sciences, University of Birjand, Birjand, Iran.
3 3. Professor of Exercise Physiology, Faculty of Sports Sciences, University of Birjand, Birjand, Iran.
4 Professor of Clinical Biochemistry, Department of Clinical Biochemistry, School of Medicine Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
چکیده [English]

Aim:  One of the acute problems of the current human society is lack of physical activity, overweight and obesity. The aim of the present study was to investigate the effect of 8 weeks of resistance training along with spirulina consumption on total antioxidant capacity and malondialdehyde in overweight and obese men. Methods: In this research, 44 men aged 30 to 50, with a body mass index greater than 25 kg/m2, were purposefully selected and randomly divided into four groups of exercise + spirulina, exercise + placebo, spirulina and placebo. Resistance exercises were performed at 12 stations, for eight weeks and three sessions per week, in very light, light-medium and heavy intensities. The spirulina and placebo groups took two tablets (500 mg) of spirulina and placebo, respectively. Blood sampling was done before and after eight weeks, following a 12 hour overnight fast.  Results: In all groups except placebo, malondialdehyde significantly decreased (P=0.00) and total antioxidant capacity increased (P=0.00). Also, a significant difference was observed between the values ​​of malondialdehyde and total antioxidant capacity in the exercise + spirulina group with other groups (P=0.00). Exercise group + placebo and spirulina had a significant difference with placebo in terms of malondialdehyde and total antioxidant capacity (P=0.00). Exercise+placebo and spirulina group had no significant difference in the mentioned values ​​(P=0.95).. Conclusions: Probably, the combination of resistance training and spirulina can have a positive effect on the peroxidative and antioxidant balance in overweight and obese men and prevent oxidative stress caused by exercise as well as overweight and obesity.

کلیدواژه‌ها [English]

  • Resistance exercise
  • Spirulina
  • Malondialdehyde
  • Antioxidant
  • Oxidative stress

Publisher: Azarbaijan Shahid Madani University          Copyright © The Authors   

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

مراجع

  1. Hecksteden A, Wegmann M, Steffen A, Kraushaar J, Morsch A, Ruppenthal S, et al. Irisin and exercise training in humans – Results from a randomized controlled training trial. BMC Medicine. 2013;11(1):235.
  2. Malek M. Is Obesity a Disease? Yes. Iranian Journal of Endocrinology and Metabolism. 2021(6):449-53 [In Persian].
  3. Carbone S, Del Buono MG, Ozemek C, Lavie CJ. Obesity, risk of diabetes and role of physical activity, exercise training and cardiorespiratory fitness. Progress in cardiovascular diseases. 2019;62(4):327-33.
  4. Kim M-J, Park M, Jeong MK, Yeo J, Cho W-I, Chang P-S, et al. Radical scavenging activity and anti-obesity effects in 3T3-L1 preadipocyte differentiation of Ssuk (Artemisia princeps Pamp.) extract. Food Science and Biotechnology. 2010;19(2):535-40.
  5. Olusi S. Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotectic enzymes in humans. International journal of obesity. 2002;26(9):1159-64.
  6. Khan SA, Ali A, Khan SA, Zahran SA, Damanhouri G, Azhar E, et al. Unraveling the complex relationship triad between lipids, obesity, and inflammation. Mediators of inflammation. 2014;2014.
  7. Urso ML, Clarkson PM. Oxidative stress, exercise, and antioxidant supplementation. Toxicology. 2003;189(1-2):41-54.
  8. Atashak S, Peeri M, Azarbayjani MA, Stannard SR, Haghighi MM. Obesity-related cardiovascular risk factors after long-term resistance training and ginger supplementation. Journal of sports science & medicine. 2011;10(4):685 [In Persian].
  9. Hosseini M, Mogharnasi M, Zafarmand O. The effect of eight weeks of concurrent training on Insulin resistance and plasma Resistin and Glucose levels in overweight and obese middle-aged men. Journal of Applied Health Studies in Sport Physiology. 2022;9(1):35-47 [In Persian].
  10. Radak Z, Chung HY, Goto S. Systemic adaptation to oxidative challenge induced by regular exercise. Free Radical Biology and Medicine. 2008;44(2):153-9.
  11. Ismaeel A, Holmes M, Papoutsi E, Panton L, Koutakis P. Resistance training, antioxidant status, and antioxidant supplementation. International journal of sport nutrition and exercise metabolism. 2019;29(5):539-47.
  12. Inal M, AKYÜZ F, Turgut A, Getsfrid WM. Effect of aerobic and anaerobic metabolism on free radical generation swimmers. Medicine & Science in Sports & Exercise. 2001;33(4):564-7.
  13. Ji LL. Free radicals and antioxidants in exercise and sports. Exercise and sport science. 2000:299-317.
  14. McBRIDE JM, Kraemer WJ, Triplett-McBride T, Sebastianelli W. Effect of resistance exercise on free radical production. Medicine and science in sports and exercise. 1998;30(1):67-72.
  15. Azizbeigi Boukani K, Atashak S, Etemad Z, Mohammad Zadeh Salamat K, Yekta Yar M. Effect of moderate-intensity resistance exercise training on plasma antioxidant capacity and inflammation factors in healthy males. Scientific Journal of Kurdistan University of Medical Sciences. 2013;18(4):1-7 [In Persian].
  16. Azizbeigi K, Azarbayjani MA, Peeri M, Agha-Alinejad H, Stannard S. The effect of progressive resistance training on oxidative stress and antioxidant enzyme activity in erythrocytes in untrained men. International journal of sport nutrition and exercise metabolism. 2013;23(3):230-8 [In Persian].
  17. Parise G, Brose AN, Tarnopolsky MA. Resistance exercise training decreases oxidative damage to DNA and increases cytochrome oxidase activity in older adults. Experimental gerontology. 2005;40(3):173-80.
  18. LIU JF, CHANG WY, CHAN KH, TSAI WY, LIN CL, HSU MC. Blood lipid peroxides and muscle damage increased following intensive resistance training of female weightlifters. Annals of the New York Academy of Sciences. 2005;1042(1):255-61.
  19. Azizbeigi K, Azarbayjani M, Peeri M. Agha alinejad H, Stannard S. The effect of progressive resistance training on oxidative stress and antioxidant enzyme activity in erythrocytes in untrained men. Int J Sport Nutr Exerc Metab. 2013;23(3):230 [In Persian].
  20. Amini H, Azarbayjani MA, Azizbeigi Boukani K. The Effect of 8 Weeks of Resistance Training on Gene Expression Lymphocyte Antioxidant Enzymes and Malondialdehyde in Healthy Inactive Men. Qom University of Medical Sciences Journal. 2018;12(2):74-83 [In Persian].
  21. Atashak S. SHarafi h, Azarbayjani M, Goli A, Batorak K. Karimi V Effect of omega-3 fatty acid supplementation on lipid peroxidation and total antioxidant capacity of plasma following a resistance exercise session in young athletes Sci J Kurdistan Univ Med Sci. 2013;17:51-9 [In Persian].
  22. Kordi MR, Attarzade Hosseini SR, Davaloo T. Aerobic exercises and Supplement Spirulina reduce inflammation in diabetic men. Journal of Jahrom University of Medical Sciences. 2018;16(4):10-8 [In Persian].
  23. Chacón‐Lee T, González‐Mariño G. Microalgae for “healthy” foods—possibilities and challenges. Comprehensive reviews in food science and food safety. 2010;9(6):655-75.
  24. Fabregas J, Herrero C. Vitamin content of four marine microalgae. Potential use as source of vitamins in nutrition. Journal of Industrial Microbiology and Biotechnology. 1990;5(4):259-63.
  25. Lu H-K, Hsieh C-C, Hsu J-J, Yang Y-K, Chou H-N. Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress. European journal of applied physiology. 2006;98(2):220-6.
  26. Nikseresht M, Agha-Alinejad H, Azarbayjani MA, Ebrahim K. Effects of nonlinear resistance and aerobic interval training on cytokines and insulin resistance in sedentary men who are obese. The Journal of Strength & Conditioning Research. 2014;28(9):2560-8 [In Persian].
  27. Brzycki M. A practical approach to strength training: Masters Press Grand Rapids, MI; 1989.
  28. Ghazizahedi S, Nouri M, Norouzy A, Nemati M, Safarian M, Mohajeri SA, et al. Scientific: validity and reproducibility of Iranian food frequency questionnaire. 2014 [In Persian].
  29. Gholamimoghadam S, Mogharnasi M. The Effect of Spirulina Supplementation and Circuit Resistance Training (CRT) on Plasma Values of Resistin, and Some Indicators of Body Composition of Overweight, and Obese Police Officers. Journal of Police Medicine. 2021;10(3):149-58 [In Persian].
  30. Dehghani K, Mogharnasi M, Sarir H, Malekaneh M. Changes in lipocalin-2 levels after resistance training (RT) and consumption of spirulina microalgae in overweight and obese men. KAUMS Journal (FEYZ). 2021:0- [In Persian].
  31. Dehghani K, Mogharnasi M, Saghebjoo M, Sarir H, Malekaneh M. The effect of eight weeks of circuit resistance training and spirulina supplementation on plasma levels of irisin and some body composition in overweight and obese men. Armaghane danesh. 2020;25(3):332-45 [In Persian].
  32. Fallah E, Agha-Alinejad H, Peeri M, Samadi M, editors. The effect of 8 weeks of resistance training with L-carnitine supplementation on total antioxidant capacity and lipid peroxidation in untrained men. 9th International Congress on Physical Education and Sport Sciences; 2016 [In Persian].
  33. Dantas FFO, Brasileiro-Santos MdS, Batista RMF, do Nascimento LS, Castellano LRC, Ritti-Dias RM, et al. Effect of strength training on oxidative stress and the correlation of the same with forearm vasodilatation and blood pressure of hypertensive elderly women: a randomized clinical trial. PloS one. 2016;11(8):e0161178.
  34. Alikhani S, Sheikholeslami‐Vatani D. Oxidative stress and anti‐oxidant responses to regular resistance training in young and older adult women. Geriatrics & Gerontology International. 2019;19(5):419-22 [In Persian].
  35. Bouzid MA, Hammouda O, Matran R, Robin S, Fabre C. Low intensity aerobic exercise and oxidative stress markers in older adults. Journal of Aging and Physical Activity. 2014;22(4):536-42.
  36. Samjoo I, Safdar A, Hamadeh M, Raha S, Tarnopolsky M. The effect of endurance exercise on both skeletal muscle and systemic oxidative stress in previously sedentary obese men. Nutrition & diabetes. 2013;3(9):e88-e [In Persian].
  37. Azizbeigi K, Azarbayjani MA, Peeri M, Agha-alinejad H, Stannard S. The effect of progressive resistance training on oxidative stress and antioxidant enzyme activity in erythrocytes in untrained men. Int J Sport Nutr Exerc Metab. 2013;23(3):230-8 [In Persian].
  38. Ahmadiasl N, Najafipour H, Soufi FG, Jafari A. Effect of short-and long-term strength exercise on cardiac oxidative stress and performance in rat. Journal of physiology and biochemistry. 2012;68(1):121-8 [In Persian].
  39. Rall LC, Roubenoff R, Meydani SN, Han SN, Meydani M. Urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG) as a marker of oxidative stress in rheumatoid arthritis and aging: effect of progressive resistance training. The Journal of nutritional biochemistry. 2000;11(11-12):581-4.
  40. McAnulty SR, McAnulty LS, Nieman DC, Morrow JD, Utter AC, Dumke CL. Effect of resistance exercise and carbohydrate ingestion on oxidative stress. Free radical research. 2005;39(11):1219-24.
  41. Marwick TH, Hordern MD, Miller T, Chyun DA, Bertoni AG, Blumenthal RS, et al. Exercise training for type 2 diabetes mellitus: impact on cardiovascular risk: a scientific statement from the American Heart Association. Circulation. 2009;119(25):3244-62.
  42. Aissaoui O, Amiali M, Bouzid N, Belkacemi K, Bitam A. Effect of Spirulina platensis ingestion on the abnormal biochemical and oxidative stress parameters in the pancreas and liver of alloxan-induced diabetic rats. Pharmaceutical biology. 2017;55(1):1304-12.
  43. Balakrishnan S, Anuradha C. Exercise, depletion of antioxidants and antioxidant manipulation. Cell Biochemistry and Function: Cellular biochemistry and its modulation by active agents or disease. 1998;16(4):269-75.
  44. Gad AS, Khadrawy YA, El-Nekeety AA, Mohamed SR, Hassan NS, Abdel-Wahhab MA. Antioxidant activity and hepatoprotective effects of whey protein and Spirulina in rats. Nutrition. 2011;27(5):582-9.
  45. Leaf DA, Kleinman MT, Hamilton M, Deitrick RW. The exercise-induced oxidative stress paradox: the effects of physical exercise training. The American journal of the medical sciences. 1999;317(5):295-300.
  46. Golestani F, Mogharnasi M, Erfani-Far M, Abtahi-Eivari SH. The effects of spirulina under high-intensity interval training on levels of nesfatin-1, omentin-1, and lipid profiles in overweight and obese females: A randomized, controlled, single-blind trial. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences. 2021;26 [In Persian].
  47. MA A. Effects of combination of long-term ginger consumption and resistance training on lipid peroxidation and insulin resistance in obese men. 2012.
مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 10، شماره 1
فروردین 1402
صفحه 39-49

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  • تاریخ دریافت: 18 مرداد 1401
  • تاریخ بازنگری: 29 مهر 1401
  • تاریخ پذیرش: 30 مهر 1401

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