تاثیر هشت هفته تمرین مقاومتی همراه با مصرف عصاره خارخاسک بر شاخص های آنتی اکسیدانی بافت هیپوکمپِ موش های صحرایی نر درمعرض استانازول

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 گروه تربیت بدنی وعلوم ورزشی، دانشگاه آزاد اسلامی، واحد محلات، محلات، ایران.

2 گروه تربیت بدنی و علوم ورزشی، دانشکده علوم ورزشی، دانشگاه اراک، اراک، ایران

چکیده

هدف: امروزه بهره گیری از مواد نیروزا به معضل پیچیده­ای در ورزش تبدیل شده است، از طرفی تمرین مقاومتی و گیاه خارخاسک تاثیر گذاری زیادی در کنترل فشار اکسایشی دارد اما تعامل تاثیر تمرین مقاومتی همراه با گیاه خارخاسک و استانازول بر ظرفیت آنتی اکسیدانی کم­تر بررسی شده است. از این رو  هدف مطالعه حاضر بررسی تاثیر هشت هفته تمرین مقاومتی همراه با مصرف عصاره خارخاسک بر شاخص­های سوپر اکسیددیسموتاز (SOD)، گلوتاتیون پراکسیداز (GPX) و کاتالاز (CAT) بافت هیپوکمپِ موش­های صحرایی نر در معرض استانازول بود. روش شناسی: در این مطالعه تجربی 56 سر موش صحرایی نر با محدوده وزن 150 تا 200 گرم و میانگین سنی 8 هفته، انتخاب و در 7 گروه 8 سری شامل 1) کنترل (C)، 2) مصرف استانازول (S)، 3) مصرف استانازول همراه با mg/kg 100 خارخاسک (ST100)، 4) مصرف استانازول همراه با mg/kg 50 خارخاسک (ST50)، 5) مصرف استانازول همراه با تمرین مقاومتی (SRT)، 6) مصرف استانازول همراه با تمرین مقاومتی و mg/kg 100 خارخاسک (SRTT100) و 7) مصرف استانازول همراه با تمرین مقاومتی و mg/kg 50 خارخاسک (SRTT50) تقسیم شدند. در مدت هشت هفته گروه های 2- 7 روزانه mg/kg 5 استانازول به صورت صفاقی دریافت نمودند؛ گروه­های 5- 7 سه جلسه در هفته با شدت 30 تا 100درصد وزن بدن، تمرینات مقاومتی انجام دادند و گروه­های 3، 4، 6 و 7 روزانه دوزهای معین خارخاسک را به صورت صفاقی دریافت نمودند. برای تحلیل داده‌ها از آنالیز واریانس یک طرفه و آزمون توکی استفاده شد (05/0>p). یافته‌ها: مصرف ST سبب کاهش SOD، GPX و CAT در هیپوکمپ شد (05/0P<). با این وجود SRT باعث افزایش معناداری سطوح SOD،GPX  و CAT شد (05/0P<). همچنین ST50 و ST100  تاثیر معناداری بر افزایش سطوح SOD و GPX داشتند (05/0P<).SRTT100  و SRTT50 اثر معناداری بر افزایش سطوح SOD، GPX و CAT داشت (05/0P≤). SRTT100  اثر بیشتری بر افزایش سطوح SOD داشت (05/0P<)، در حالی که سطوح CAT در SRTT50 افزایش بیشتری داشت (05/0P<). نتیجه‌گیری: به نظر می­رسد تمرین مقاومتی و مصرف خارخاسک به طور مجزا اثرات موثری بر بهبود شاخص­های آنتی اکسیدانی دارند، با این وجود انجام تمرین مقاومتی و مصرف مکمل خارخاسک می­تواند اثرات مطلوب­تری نسبت به هر مداخله به تنهایی بر شاخص­های آنتی اکسیدانی بافت هیپوکمپ ناشی از مسمومیت استانازول داشته باشد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of eight weeks of resistance training with consumption of Tribulus terrestris extract on antioxidant indices of hippocampal tissue in male rats exposed to stanazol

نویسندگان [English]

  • Behnam Shamsi 1
  • Bahram Abedi 1
  • Sajjad Ramezani 2
1 Department of Physical Education and Sport Sciences, Islamic Azad University, Mahallat Branch, Mahallat, Iran.
2 Department of Physical Education and Sports Science, Faculty of Sports Sciences, Arak University, Arak, Iran
چکیده [English]

Aim:   Today, the use of energizers has become a complex problem in sports. On the other hand, resistance training and Tribulus terrestris have a great effect on controlling oxidative stress, but the interaction of resistance training with Tribulus terrestris and Stanazol on low antioxidant capacity. More reviewed. Therefore, the aim of this study was to investigate the effect of eight weeks of resistance training with consumption of Tribulus terrestris extract on the levels of superoxide dismutase (SOD), glutathione peroxidase (GPX) and catalase (CAT) in the hippocampal tissue of male rats exposed to stanazol. Methods: In this experimental study, 56 male rats with a weight range of 150 to 200 g and a mean age of 8 weeks were selected and included in 7 groups of 8 series including 1) control (C), 2) stanazol (S), 3) stanazol with 100 mg / kg of tribulus terrestris (ST100), 4) Taking Stanazol with 50 mg / kg of tribulus terrestris (ST50), 5) Taking Stanazol with resistance training (SRT), 6) Taking Stanazol with resistance training and 100 mg / kg of tribulus terrestris (SRTT100) and 7) Taking Stanazol with training Resistance and 50 mg / kg of tribulus terrestris (SRTT50) were divided. For eight weeks, the 2-7 groups received 5 mg / kg daily of stanazole peritoneally;  Groups 5-7 performed resistance exercises three sessions a week with an intensity of 30 to 100% of their body weight and groups 3, 4, 6 and 7 received certain doses of tribulus terrestris daily.  One-way analysis of variance with Tukey post hoc test was used to analyze the findings (p <0.05). Results: Consumption of S had a significant effect on reducing SOD, GPX and CAT levels in rat hippocampal tissue (P<0.05), however, SRT significantly increased SOD, GPX and CAT levels (P<0.05), as well as ST50 and ST100. They had a significant effect on increasing SOD and GPX levels (P<0.05). SRTT100 and SRTT50 had a significant effect on increasing SOD, GPX and CAT levels (P<0.05). SRTT100 had a greater effect on increasing SOD levels (P<0.05), while CAT levels had a greater increase in SRTT50 (P<0.05).Conclusions:  It seems that resistance training and consumption of tribulus terrestris separately have effective effects on improving antioxidant indices, however, resistance training and consumption of tribulus terrestris supplementation can have more favorable effects than any intervention alone on Have antioxidant properties of hippocampal tissue due to stanazole poisoning.

کلیدواژه‌ها [English]

  • Resistance training
  • Hippocampus
  • Antioxidant
  • Stanazol
  • Tribulus terrestris

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 9، شماره 1
فروردین 1401
صفحه 48-60

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سابقه مقاله

  • تاریخ دریافت: 11 بهمن 1400
  • تاریخ بازنگری: 06 اردیبهشت 1401
  • تاریخ پذیرش: 09 اردیبهشت 1401

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