تاثیر هشت هفته تمرین ورزشی ترکیبی بر مقادیر لپتین و آدیپونکتین پلاسمای پسران چاق

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 دانشجوی دکترای فیزیولوژی ورزش، پژوهشگاه تربیت بدنی و علوم ورزشی. تهران، ایران.

2 استادیار فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، پژوهشگاه تربیت بدنی و علوم ورزشی، تهران، ایران.

3 استاد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی، تهران، ایران.

4 استادیار فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، پژوهشگاه تربیت بدنی و علوم ورزشی، تهران، ایران

چکیده

هدف: آدیپوسیتوکین‌ها نقش مهمی در کنترل هومئوستاز انرژی و فرآیندهای متابولیکی مختلف مربوط به چاقی دارند. لذا، هدف از مطالعه حاضر، بررسی تاثیر 8 هفته تمرین ورزشی ترکیبی بر سطوح لپتین و آدیپونکتین پلاسمای پسران چاق بود. روش شناسی: 40 پسر چاق (46/0 ± 7/12 ساله، با وزن 19/10 ± 46/78 کیلوگرم، قد 16/8 ± 7/161 سانتی‌متر و چربی بدن 30/4 ± 04/33 درصد) به دو گروه تمرین ورزشی ترکیبی و کنترل تقسیم شدند. آزمودنی های گروه تمرین ترکیبی در یک برنامه ترکیبی هوازی (30 دقیقه) و مقاومتی (یک نوبت از 7 حرکت مقاومتی)، 3 جلسه در هفته برای 8 هفته شرکت کردند، در حالی‌که گروه کنترل هیچ فعالیت ورزشی منظمی نداشتند و به فعالیت های معمول روزانه خود ادامه دادند.  قبل و پس از برنامه تمرین ورزشی، توده بدن، چربی بدن، سطوح لپتین، آدیپونکتین پلاسما اندازه‌گیری شد. داده ها با استفاده از تی مستقل و تی زوجی مقایسه شدند. یافته‌ها: مقایسه بین گروهی نشان داد که درصد چربی بدن (42/0 = P)، وزن بدن (88/0 = P) و سطح پلاسمایی لپتین (065= P) پس از تمرینات ورزشی ترکیبی تغییر معنی داری نداشت؛ با این حال، سطح آدیپونکتین پلاسما ( 001/0 = P) و نسبت آدیپونکتین به درصد چربی بدن (014/0 = P) در پاسخ به تمرین ورزشی ترکیبی افزایش معنی داری داشت. نتیجه‌گیری: نتایج نشان داد که 8 هفته تمرین ورزشی ترکیبی سطح آدیپونکتین پلاسما را در چاقی دوران کودکی افزایش می دهد. بعلاوه، فعالیت بدنی منظم بدون تغییرات همزمان در سطح ترکیب بدن، تاثیر معنی داری بر سطح لپتین نداشت.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Effect of 8-weeks of Combined Exercise Training on Plasma Leptin and Adiponectin levels in Obese Boys

نویسندگان [English]

  • Ali Akbar Jahandideh 1
  • Hadi Rohani 2
  • Hamid Rajabi 3
  • Mohammad Shariatzade Joneidi 4
1 PhD student in sports physiology, Institute of Physical Education and Sports Sciences. Tehran Iran.
2 Assistant Professor of Sports Physiology, Department of Sports Physiology, Institute of Physical Education and Sports Sciences, Tehran, Iran
3 Professor of Sports Physiology, Faculty of Physical Education and Sports Sciences, Kharazmi University, Tehran, Iran.
4 Assistant Professor of Exercise Physiology, Department of Exercise Physiology, Sport Sciences Research Institute, Tehran, Iran
چکیده [English]

Aim: Adipocytokines play an important role in controlling energy homeostasis, and in various metabolic processes related to obesity.  Therefore, the aim of the present study is to investigate the effects of 8-week of combined exercise training on plasma leptin and adiponectin levels in obese boys.
Methods: A total of 40 obese boys (age: 12.7±0.46 years, weight 78.46±10.19 kg, height 161.72±8.16 cm, and body fat 33.04±4.30 %) were divided into two combined exercise training (CT) and control groups. Subjects in the CT group participated in a combined aerobic (30 min) and resistance (one set of 7 resistance exercises) training program 3 times/week for 8 weeks, whereas those in the control group had no regular exercise and continued their routine daily activities. Body mass, body fat, plasma leptin and adiponectin levels were measured before and after the training program.  The data were compared using Paired and ‌independent t-test.
Results: The between-group comparison showed that body fat percentage (P=0.42), body weight (P=0.88) and plasm leptin level (P=0.065) did not change significantly after combined exercise training; however, plasma adiponectin level (P=0.001) and adiponectin/ body fat (%) ratio (P= 0.014) increased significantly in response to combined exercise training.
Conclusion: The results indicated that eight-week combined exercises training increased plasma adiponectin level in childhood obesity. Furthermore, regular physical activity without simultaneous changes in body composition level had no significant effect on leptin level.

کلیدواژه‌ها [English]

  • Obesity
  • Exercise
  • Leptin
  • Adiponectin

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

مراجع

  1.  

    1. Sahranavard E, Amiri S, Ghofrani M. Effect Eight Week of Combined Aerobic-Resistance Exercise Training on Serum Visfatin Levels and Anthropometric Indices in Obese Young Girls. JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY,[online] 6 (2). Physiology. 2019;6(2):65-72.
    2. AZARBAYJANI MA, ABEDI B. COMPARISON OF AEROBIC, RESISTANCE AND CONCURRENT EXERCISE ON LIPID PROFILES AND ADIPONECTIN IN SEDENTARY MEN. KNOWLEDGE AND HEALTH. 2012;7(1):-.
    3. Al Kibria GM. Prevalence and factors affecting underweight, overweight and obesity using Asian and World Health Organization cutoffs among adults in Nepal: analysis of the Demographic and Health Survey 2016. Obesity research & clinical practice. 2019;13(2):129-36.
    4. Agha-Alinejad H, Gharakhanlou R, Farzad B, Bayati M. Norms of anthropometric, body composition measures and prevalence of overweight and obesity in urban populations of Iran. Journal of Shahrekord University of Medical Sciences. 2014;15(6):18-27.
    5. Abarca-Gómez L, Abdeen ZA, Hamid ZA, Abu-Rmeileh NM, Acosta-Cazares B, Acuin C, et al. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128· 9 million children, adolescents, and adults. The lancet. 2017;390(10113):2627-42.
    6. Maddah M. Overweight and obesity among Iranian female adolescents in Rasht: more overweight in the lower social group. Public health nutrition. 2007;10(5):450-3.
    7. Serdula MK, Ivery D, Coates RJ, Freedman DS, Williamson DF, Byers T. Do obese children become obese adults? A review of the literature. Preventive medicine. 1993;22(2):167-77.
    8. García-Hermoso A, Ceballos-Ceballos R, Poblete-Aro C, Hackney A, Mota J, Ramírez-Vélez R. Exercise, adipokines and pediatric obesity: a meta-analysis of randomized controlled trials. International journal of obesity. 2017;41(4):475-82.
    9. Barseghian A, Gawande D, Bajaj M. Adiponectin and vulnerable atherosclerotic plaques. Journal of the American College of Cardiology. 2011;57(7):761-70.
    10. Sabbatini AR, Fontana V, Laurent S, Moreno H. An update on the role of adipokines in arterial stiffness and hypertension. Journal of hypertension. 2015;33(3):435-44.
    11. Ronti T, Lupattelli G, Mannarino E. The endocrine function of adipose tissue: an update. Clinical endocrinology. 2006;64(4):355-65.
    12. Larijani B, Ghodsi M. Leptin: A new adypocyte hormone and its role in the obesity. Iranian Journal of Diabetes and Metabolism. 2005;4(3):1-10.
    13. Maddah M, Jazayery A, Mirdamadi R, Eshraghiyan MR, Jalali M. Sex hormones, leptin and anthropometric indices in men. Journal of Reproduction & Infertility. 2001;2(2).
    14. Mohiti-Ardakani J, Afkhami-Ardakani M, Sedghi H. Comparitive Study of Serum Leptin Levels in Diabetic Obese Patients and Non-Diabetic Obese Individuals. SSU_Journals. 2004;12(2):9-14.
    15. Enriori PJ, Evans AE, Sinnayah P, Cowley MA. Leptin resistance and obesity. Obesity. 2006;14(S8):254S-8S.
    16. Venner AA, Lyon ME, Reimer RA, Doyle-Baker PK. Changes in leptin and adiponectin concentrations during a high intensity exercise intervention programme for obese children.
    17. Mahawar KK, De Alwis N, Carr WR, Jennings N, Schroeder N, Small PK. Bariatric surgery in type 1 diabetes mellitus: a systematic review. Obesity surgery. 2016;26(1):196-204.
    18. Matsubara M, Maruoka S, Katayose S. Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women. European journal of endocrinology. 2002;147(2):173-80.
    19. Balagopal P, George D, Yarandi H, Funanage V, Bayne E. Reversal of obesity-related hypoadiponectinemia by lifestyle intervention: a controlled, randomized study in obese adolescents. The Journal of Clinical Endocrinology & Metabolism. 2005;90(11):6192-7.
    20. Bouassida A, Chamari K, Zaouali M, Feki Y, Zbidi A, Tabka Z. Review on leptin and adiponectin responses and adaptations to acute and chronic exercise. British journal of sports medicine. 2010;44(9):620-30.
    21. Khajehlandi M, Bolboli L, Siahkuhian M, Nikseresht F. Effect of pilates training on serum levels of adiponectin and leptin in inactive women with overweight. Journal of Jiroft University of Medical Sciences. 2018;4(2):201-12.
    22. Azali Alamdari K, khalafi M, Ghorbanian B. Effect of Aerobic Training on Serum Adiponectin and Ctrp-3 in Males with Metabolic Syndrome. Iranian Journal of Endocrinology and Metabolism. 2017;18(5):368-77.
    23. Azali Alamdari k, Khodaei O. The effect of high intensity interval training on serum adiponectin, insulin resistance and markers of metabolic syndrome in men with metabolic syndrome. Journal of Applied Health Studies in Sport Physiology. 2018;5(1):69-76.
    24. Jha P, Khurana S, Ali K, Ahmad I, Verma S. Effects of concurrent training on physical health and performance. Comparative Exercise Physiology. 2018;14(1):63-8.
    25. Marshall WA, Tanner JM. Variations in the pattern of pubertal changes in boys. Archives of disease in childhood. 1970;45(239):13-23.
    26. Kuczmarski RJ. 2000 CDC Growth Charts for the United States: methods and development: Department of Health and Human Services, Centers for Disease Control and …; 2002.
    27. Cole TJ, Green PJ. Smoothing reference centile curves: the LMS method and penalized likelihood. Statistics in medicine. 1992;11(10):1305-19.
    28. Epley B. Poundage chart: Boyd Epley workout. Body Enterprises, Lincoln, NE. 1985;86.
    29. Montazeri Taleghani H, Soori R, Rezaeian N, Khosravi N. Changes of plasma leptin and adiponectin levels in response to combined endurance and resistance training in sedentary postmenopausal women. Koomesh. 2012;13(2):269-77.
    30. Mantzoros CS, Magkos F, Brinkoetter M, Sienkiewicz E, Dardeno TA, Kim S-Y, et al. Leptin in human physiology and pathophysiology. American Journal of Physiology-Endocrinology and Metabolism. 2011;301(4):E567-E84.
    31. Mantovani RM, Rocha NP, Magalhães DM, Barbosa IG, Teixeira AL. Early changes in adipokines from overweight to obesity in children and adolescents☆. Jornal de pediatria. 2016;92:624-30.
    32. Kishali NF. Serum leptin level in healthy sedentary young men after a short-term exercise. African Journal of Pharmacy and Pharmacology. 2011;5(4):522-6.
    33. Moran CN, Barwell ND, Malkova D, Cleland SJ, McPhee I, Packard CJ, et al. Effects of diabetes family history and exercise training on the expression of adiponectin and leptin and their receptors. Metabolism. 2011;60(2):206-14.
    34. Dâmaso AR, da Silveira Campos RM, Caranti DA, de Piano A, Fisberg M, Foschini D, et al. Aerobic plus resistance training was more effective in improving the visceral adiposity, metabolic profile and inflammatory markers than aerobic training in obese adolescents. Journal of sports sciences. 2014;32(15):1435-45.
    35. Balagopal P, Gidding SS, Buckloh LM, Yarandi HN, Sylvester JE, George DE, et al. Changes in circulating satiety hormones in obese children: a randomized controlled physical activity‐based intervention study. Obesity. 2010;18(9):1747-53.
    36. Lopes WA, Leite N, da Silva LR, Brunelli DT, Gáspari AF, Radominski RB, et al. Effects of 12 weeks of combined training without caloric restriction on inflammatory markers in overweight girls. Journal of sports sciences. 2016;34(20):1902-12.
    37. Bouassida A, Zalleg D, Bouassida S, Zaouali M, Feki Y, Zbidi A, et al. Leptin, its implication in physical exercise and training: a short review. Journal of sports science & medicine. 2006;5(2):172.
    38. Souri R, Akbari M, Kazemi A, Saei MA, Amani S. The Effect of High Intensity Training (HIT) on Serum Levels of Adiponectin and Leptin in Obese Children. Journal of Sport Biosciences. 2015;7(4):593-603.
    39. Corte de Araujo AC, Roschel H, Picanço AR, do Prado DML, Villares SMF, de Sa Pinto AL, et al. Similar health benefits of endurance and high-intensity interval training in obese children. 2012.
    40. Foroutan Y, Parnow AH, Daneshyar S. Independent and combined effects of intense aerobic training and detraining on serum levels of leptin, adiponectin and factors associated with overweight %J Journal of Applied Health Studies in Sport Physiology. 2017;4(2):34-41.
مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 8، شماره 2
مهر 1400
صفحه 25-33

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سابقه مقاله

  • تاریخ دریافت: 21 تیر 1400
  • تاریخ بازنگری: 14 مهر 1400
  • تاریخ پذیرش: 15 مهر 1400

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