نوع ژنوتیپ آلفا اکتنین-3 و تفاوت های عملکرد ورزشى پسران نوجوان غیرورزشکار ارومیه

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی واحد تبریز، تبریز، ایران

2 دانشیار فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی واحد تبریز، تبریز، ایران

چکیده

کشورهای توسعه یافته با بررسی فراوانی ژن های مرتبط با عملکرد ورزشی در جهت پیشبرد اهداف ورزش قهرمانی جامعه برنامه ریزی صحیح تری ارئه نموده اند، ولی در کشورهای در حال توسعه در این زمینه پژوهش ها کمتری صورت گرفته است. بر این اساس، هدف پژوهش حاضر، بررسی پلی مورفیزم ژن آلفا اکتنین-3 و تفاوت عملکرد ورزشی پسران 10-12 ساله غیر ورزشکار ارومیه بود. آزمودنی های پژوهش نیمه تجربی حاضر شامل 123 نفر پسر 10 تا 12 سالۀ غیر ورزشکار سالم بودند که در مرحلۀ دوم بلوغ تانر قرار داشتند. DNA ژنومی بزاقی با استفاده از کیت مربوطه استخراج شده و بررسی پلی مورفیزم های مورد نظر به روش PCR- RFLP انجام گردید. برای مقایسه میانگین عملکردهای مختلف ورزشی، در ابتدا آزمودنیها بر اساس سه نوع پلی مورفیزم آلفا اکتنین-3 طبقه بندی شده و میانگین عملکردهای ورزشی سه گروه بطور جداگانه با روش آنالیز کواریانس یک طرفه (آنکووا) مقایسه گردید. سطح معنی داری با 95 درصد اطمینان در نظر گرفته شد. یافته های این پژوهش نشان داد که ژنوتیپ XX بر عملکرد استقامتی تأثیر معنی داری داشته، ولی ژنوتیپ های آلفا اکتنین-3 بر عملکرد سرعتی و قدرتی آزمودنیها تأثیر معنی داری نداشت. نتایج این پژوهش نشان داد که علیرغم تأثیر ژنوتیپ XX بر عملکرد استقامتی، نمی توان این ژن را عامل تعیین کننده ای در عملکرد های سرعتی و قدرتی دانست.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

ACTN3 Genotype and Some Athletic Performance Variants of Non-Athletic Adolescents Boys of Urmia

نویسندگان [English]

  • Farinaz Farrokh Pour 1
  • Farzad Zehsaz 2
1 MSc in exercise physiology, department of physical education and sport science, Islamic Azad University, Tabriz Branch.
2 Associate professor, department of physical education and sport science, Islamic Azad University, Tabriz Branch.
چکیده [English]

Developed countries have presented a better plan for evaluating the frequency of genes related to sport performance in order to promote the goals of championship sports of the community, but less research has been done in developing countries. Accordingly, the aim of this study was to investigate ACTN3 gene polymorphism and some athletic performances of non-athlete male adolescents of Urmia. The subjects of the semi-experimental study were 123 healthy non-athletic boys who were in the second stage of Tanner's maturity. DNA genome of SALIVA was extracted using a suitable kit and the study of polymorphisms was performed by PCR- RFLP method. In order to compare the mean of different exercise performance, at first the subjects were categorized based on three types of ACTN3 polymorphism, then the means of exercise performance of the three groups were separately compared with one-way covariance analysis (ANCOVA). The significant level of p < 0.05 was considered. results: The findings of this study showed that genotype XX has a significant effect on the endurance function, but genotypes ACTN3 does not have the significant effect on the speed and strength performance of subjects. The results of this study showed that despite the effect of genotype XX on the endurance performance, this gene polymorphism cannot be considered as a determinant factor in speed and strength performance.

کلیدواژه‌ها [English]

  • polymorphism
  • ACTN3
  • genotype
  • Adolescents
  • exercise performance

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مطالعات کاربردی تندرستی در فیزیولوژی ورزش
دوره 5، شماره 2
مهر 1397
صفحه 45-53

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  • تاریخ دریافت: 07 بهمن 1397
  • تاریخ بازنگری: 17 فروردین 1398
  • تاریخ پذیرش: 14 اردیبهشت 1398

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