تاثیر تمرینات پیلاتس بر محتوای چربی کبد و آنزیم‌های کبدی در مردان مبتلا به کبد چرب غیرالکلی

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

1 موسسه آموزش عالی غیرانتفاعی علامه قزوینی، قزوین، ایران.

2 گروه تربیت بدنی و علوم ورزشی، دانشکده علوم اجتماعی، دانشگاه بین المللی امام خمینی(ره)، قزوین، ایران

چکیده

زمینه و هدف: بیماری کبد چرب غیرالکلی (NAFLD) که با تجمع و رسوب چربی در سلول‌های کبدی همراه است، از عوامل خطر جدی برای سایر بیماری‌ها مانند قلبی عروقی و دیابت بشمار می‌آید. بنابراین، مطالعه حاضر با هدف بررسی تاثیر تمرینات پیلاتس بر محتوای چربی کبد و آنزیم‌های کبدی در مردان میانسال مبتلا به کبد چرب غیرالکلی انجام شد. روش کار: بیست مرد میانسال مبتلا به NAFLD به طور تصادفی به دو گروه تمرین پیلاتس و کنترل تقسیم شدند. گروه تمرین پیلاتس به مدت هشت هفته در برنامه تمرینات پیلاتس شرکت کردند. برخی متغیرهای ترکیب بدنی و آنتروپومتریک، محتوای چربی کبد و سطح سرمی آنزیم‌های ALT، AST و ALP قبل و بعد از دوره تمرین ارزیابی شدند. داده‌ها با استفاده از آزمون‌های t زوجی و t مستقل تجزیه و تحلیل شدند. یافته‌ها: پس از هشت هفته تمرین پیلاتس، محتوای چربی کبد در گروه تمرین پیلاتس در مقایسه با گروه کنترل کاهش معنی‌داری نشان داد. همچنین، سطح سرمی آنزیم‌های ALT، AST و ALP در گروه تمرین پیلاتس نسبت به گروه کنترل به طور قابل توجهی کاهش یافت. به علاوه، هشت هفته تمرین پیلاتس باعث کاهش معنی‌داری در وزن بدن، BMI، درصد چربی و نسبت دور کمر به باسن شد در حالی که تغییر معنی‌داری در گروه کنترل مشاهده نشد. نتیجه‌گیری: نتایج مطالعه حاضر حاکی از آن بود که تمرینات پیلاتس می‌تواند در بهبود محتوای چربی کبد و نیز کاهش سطح سرمی آنزیم‌های کبدی ALT، AST و ALP در مردان میانسال مبتلا به کبد چرب غیرالکلی موثر باشد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Effect of Pilates Training on Hepatic Fat Content and Liver Enzymes in Men with Nonalcoholic Fatty Liver Disease

نویسندگان [English]

  • Ziba Keymasi 1
  • Abbas Sadeghi 2
  • Hassan Pourrazi 2
1 Allame Gazvini Institute, Qazvin, Iran.
2 Department of Physical Education, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran
چکیده [English]

Objectives: Non-alcoholic fatty liver disease (NAFLD), which is associated with fat accumulation and deposition in liver cells, is a serious risk factor for other diseases, such as cardiovascular disease and diabetes. The aim of this study was to investigate the effect of Pilates training on the hepatic fat content and liver enzymes in middle-aged men with NAFLD.
Methods: 20 middle-aged men with NAFLD were randomly divided into Pilates training and control groups. The Pilates group participated in the Pilates training program for eight weeks. The body composition, anthropometric indices, liver fat content, and serum levels of ALT, AST and ALP were measured before and after the training period. Data were analyzed using paired t-test and independent t-test at a significance level of 0.05.
Results: After eight weeks of Pilates training, the liver fat content in the Pilates group was significantly lower than that of the control group. Also, the serum levels of ALT, AST, and ALP significantly decreased in the Pilates group, compared to the controls. In addition, eight weeks of Pilates training significantly reduced the body weight, body mass index (BMI), fat percentage, and waist-to-hip ratio of patients, while no significant changes were observed in the control group.
Conclusion: The results of the present study indicated that Pilates training could be effective in improving the liver fat content and reducing the serum levels of ALT, AST, and ALP in middle-aged men with NAFLD.

کلیدواژه‌ها [English]

  • Pilates
  • Hepatic fat content
  • Liver enzymes
  • Non-alcoholic fatty liver disease
1. Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease—meta‐analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73-84 .
2. Damor K, Mittal K, Bhalla AS, Sood R, Pandey RM, Guleria R, et al. Effect of progressive resistance exercise training on hepatic fat in asian indians with non-alcoholic fatty liver disease. Journal of Advances in Medicine and Medical Research. 2014:114-24.
3. Arshad T, Golabi P, Paik J, Mishra A, Younossi ZM. Prevalence of Nonalcoholic Fatty Liver Disease in the Female Population. Hepatology communications. 2019;3(1):74-83.
4. Ryoo J-H, Choi J-M, Moon SY, Suh YJ, Shin J-Y, Shin HC, et al. The clinical availability of non alcoholic fatty liver disease as an early predictor of the metabolic syndrome in Korean men: 5-year's prospective cohort study. Atherosclerosis. 2013;227(2):398-403.
5. St. George A, Bauman A, Johnston A, Farrell G, Chey T, George J. Independent effects of physical activity in patients with nonalcoholic fatty liver disease. Hepatology. 2009;50(1):68-76.
6. Kistler KD, Brunt EM, Clark JM, Diehl AM, Sallis JF, Schwimmer JB. Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. The American journal of gastroenterology. 2011.
7. Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, et al. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Gut. 2011;60(9):1278-83.
8. Association AG. American Gastroenterological Association medical position statement: nonalcoholic fatty liver disease. Gastroenterology. 2002;123:1702-4.
9. Hagner-Derengowska M, Kałużny K, Budzyński J. Effects of Nordic Walking and Pilates training programs on aminotransferase activity in overweight and obese elderly women. Journal of Education, Health and Sport. 2015;5 .)21(
10. Aladro-Gonzalvo AR, Machado-Díaz M, Moncada-Jiménez J, Hernández-Elizondo J, Araya-Vargas G. The effect of Pilates exercises on body composition: a systematic review. Journal of bodywork and movement therapies. 2012;16(1):109-14.
11. Mir p, Mir z. Effect of 8 weeks pilates exercise on plasma visfatin and insulin resistance index in obese women. Nursing of the Vulnerables. 2016;3(8):1-12.
12. Marinda F, Magda G, Ina S, Brandon S, Abel T, Ter Goon D. Effects of a mat pilates program on cardiometabolic parameters in elderly women. Pakistan journal of medical sciences. 2013;29(2):500.
13. Lim HS, Yoon S. The effects of Pilates exercise on cardiopulmonary function in the chronic stroke patients: a randomized controlled trials. Journal of physical therapy science. 2017;29(5):959-63.
14. Houghton D, Thoma C, Hallsworth K, Cassidy S, Hardy T, Burt AD, et al. Exercise reduces liver lipids and visceral adiposity in patients with nonalcoholic steatohepatitis in a randomized controlled trial. Clinical Gastroenterology and Hepatology. 2017;15(1):96-102. e3.
15. Hallsworth K, Thoma C, Hollingsworth KG ,Cassidy S, Anstee QM, Day CP, et al. Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial. Clinical science. 2015;129(12):1097-105.
16. Haus JM, Solomon TP, Kelly KR, Fealy CE, Kullman EL, Scelsi AR, et al. Improved hepatic lipid composition following short-term exercise in nonalcoholic fatty liver disease. The Journal of Clinical Endocrinology & Metabolism. 2013;98(7):E1181-E8.
17. Hashida R, Kawaguchi T, Bekki M, Omoto M, Matsuse H, Nago T, et al. Aerobic vs. resistance exercise in non-alcoholic fatty liver disease: A systematic review. Journal of hepatology. 2017;66(1):142-52.
18. Guo R, Liong EC, So KF, Fung M-L, Tipoe GL. Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease. Hepatobiliary & Pancreatic Diseases International. 2015;14(2):139-44.
19. Ehsan Asghari؛ Mohammad Javad Ramezan Nejhad؛ Zahra Mir Zendeh Del. Examined the changes in serum levels of inflammatory, anti-inflammatory factors and Irisin after an acute resistance exercise in sedentary young men. Biannual Journal of Applied Health Studies in Sport Physiology. Volume 3, Issue 2, Autumn and Winter, 2015, p. 24-31.
20. Javad Vakili؛ Ramin Amir Sasan؛ Solmaz Hashem Pour؛Touhid Khanvari. Effects of Nigella Sativa short term Supplementation on superoxide dismutase and malondialdehyde Responses to a Bout of Aerobic Exercise in Male Volleyball Players. Biannual Journal of Applied Health Studies in Sport Physiology. Volume 3, Issue 2, Autumn and Winter, 2015, p. 40-46.
21. Dong F, Zhang Y, Huang Y, Wang Y, Zhang G, Hu X, et al. Long-term lifestyle interventions in middle-aged and elderly men with nonalcoholic fatty liver disease: a randomized controlled trial. Scientific reports. 2016;6:36783.
22. Keating SE, Hackett DA, George J, Johnson NA. Exercise and non-alcoholic fatty liver disease: a systematic review and meta-analysis. Journal of hepatology. 2012;57(1):157-66.
23. Singh S, Allen AM, Wang Z, Prokop LJ, Murad MH, Loomba R. Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies. Clinical Gastroenterology and Hepatology. 2015;13(4):643-54. e 9.
24. Samira Pour Mirzaei؛ Bahman Mirzaei؛ Farhad Rahmani Nia. The Prevalence of Female Athlete Triad (Eating Disorder, Amenorrhea, and Osteoporosis) and its Relation to the Level of Physical Activity in National Teams of Iran. Biannual Journal of Applied Health Studies in Sport Physiology. Volume 3, Issue 2, Autumn and Winter, 2015, p. 32-39.