تاثیر هشت هفته تمرین تناوبی بی هوازی بر آیریزین و نیمرخ لیپیدی مردان سالمند

نوع مقاله : مقاله پژوهشی Released under (CC BY-NC 4.0) license I Open Access I

نویسندگان

گروه فیزیولوژی ورزش، دانشکده علوم انسانی، دانشگاه سمنان، سمنان، ایران

چکیده

فعالیت های ورزشی منظم نقش برجسته و مهمی در فرایند سالمندی دارد. هدف از مطالعه‌ی حاضر، بررسی تاثیر هشت هفته تمرین تناوبی بی هوازی بر آیریزین و نیمرخ لیپیدی مردان سالمند بود. در این مطالعه نیمه تجربی 26 نفر از مردان سالمند شهر سمنان (سن66/3±78//63 سال) به طور در دسترس انتخاب و به طور تصادفی به دو گروه کنترل (12=n) و تمرین (14n=) تقسیم شدند. گروه تجربی تمرین تناوبی بی هوازی را با شدت 70 تا 80 درصد حداکثر ضربان قلب، به مدت هشت هفته و شش جلسه در هفته اجرا کردند. از روش الایزا برای اندازه گیری متغیرهای بیوشیمیایی استفاده شد. نتایج نشان داد که هشت هفته تمرین تناوبی بی هوازی، سطح سرمی آیریزین را به طور معنی داری افزایش داد. همچنین سطوح گلوکز و LDL به طور معنی داری کاهش یافت. بر اساس یافته های پژوهش، انجام تمرینات تناوبی بی هوازی ضمن افزایش آیریزین و ایجاد تغییرات مطلوب در نیمرخ لیپیدی، منجر به بهبود ترکیب بدنی افراد سالمند می گردد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

The effect of eight weeks' anaerobic interval training on Irisin and lipid profiles in elderly men

نویسندگان [English]

  • Hassan Abbasi
  • Rouhollah Haghshenas
Department of Sport Sciences, Faculty of Humanities, Semnan University, Semnan, Iran
چکیده [English]

Regular physical activities play a prominent role in the aging process. The purpose of this study was to investigate the effect of eight weeks anaerobic interval training on the Irisin, Insulin and lipid profiles in elderly men. In this quasi experimental study 26 elderly men from semnan city (age 63.78±3.66 years old) were selected and randomly divided into two groups of intervention (n=14) and control (n=12). The intervention group performed anaerobic interval training with 10 to 17 repetitions of 20 seconds running, 70-80% maximal heart rate and 80 second recovery. The ELISA method was used to measure biochemical variables and multivariate analysis of covariance used to analyze the data at a significant level of P≤0.05.
Findings: The results showed that 8 weeks of anaerobic interval training significantly increased the level of Irisin (P=0.001). Also, glucose levels (P=0.001) and LDL (P=0.001) decreased significantly. Based on the findings, performing anaerobic interval training, with increased of Irisin and development of lipid profile leads to improves the body composition of the elderly and brings happiness and vitality to this community of people.

کلیدواژه‌ها [English]

  • Aging
  • Irisin
  • High Intensity interval training
1. Phillips B, Williams J, Atherton P, Smith K, Hildebrandt W, Rankin D, et al. Resistance exercise training improves age-related declines in leg vascular conductance and rejuvenates acute leg blood flow responses to feeding and exercise. Journal of Applied Physiology. 2011;112(3):347-53.
2. Mora JC, Valencia WM. Exercise and older adults. Clinics in geriatric medicine. 2018;34(1):145-62.
3. Weber TA, Reichert AS. Impaired quality control of mitochondria: aging from a new perspective. Experimental gerontology. 2010;45(7-8):503-11.
4. Lind L, Sundström J, Ärnlöv J, Lampa E. Impact of Aging on the Strength of Cardiovascular Risk Factors: A Longitudinal Study Over 40 Years. Journal of the American Heart Association. 2018;7(1):e007061.
5. Chodzko-Zajko WJ. Exercise and physical activity for older adults. Kinesiology Review. 2014;3(1):101-6.
6. Santos-Parker JR, LaRocca TJ, Seals DR. Aerobic exercise and other healthy lifestyle factors that influence vascular aging. Advances in physiology education. 2014;38(4):296-307.
7. Della Gatta PA, Garnham AP, Peake JM, Cameron-Smith D. Effect of exercise training on skeletal muscle cytokine expression in the elderly. Brain, behavior, and immunity. 2014;39:80-6.
8. Boström PA, Fernández-Real JM, Mantzoros C. Irisin in humans: recent advances and questions for future research. Metabolism-Clinical and Experimental. 2014;63(2):178-80.
9. Xu X, Ying Z, Cai M, Xu Z, Li Y, Jiang SY, et al. Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2011;300(5):R1115-R25.
10. Pang M, Yang J, Rao J, Wang H, Zhang J, Wang S, et al. Time-Dependent Changes in Increased Levels of Plasma Irisin and Muscle PGC-1α and FNDC5 after Exercise in Mice. The Tohoku journal of experimental medicine. 2018;244(2):93-103.
11. Lee P, Linderman JD, Smith S, Brychta RJ, Wang J, Idelson C, et al. Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans. Cell metabolism. 2014;19(2):302-9.
12. Pérez-Sotelo D, Roca-Rivada A, Baamonde I, Baltar J, Castro A, Domínguez E, et al. Lack of Adipocyte-Fndc5/Irisin Expression and Secretion Reduces Thermogenesis and Enhances Adipogenesis. Scientific reports. 2017;7(1):16289.
13. Lecker SH, Zavin A, Cao P, Arena R, Allsup K, Daniels KM, et al. Expression of the Irisin Precursor FNDC5 in Skeletal Muscle Correlates With Aerobic Exercise Performance in Patients With Heart FailureClinical Perspective. Circulation: Heart Failure. 2012;5(6):812-8.
14. Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012;481(7382):463.
15. Kurdiova T, Balaz M, Vician M, Maderova D, Vlcek M, Valkovic L, et al. Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies. The Journal of physiology. 2014;592(5):1091-107.
16. Miyamoto-Mikami E, Sato K, Kurihara T, Hasegawa N, Fujie S, Fujita S, et al. Endurance training-induced increase in circulating irisin levels is associated with reduction of abdominal visceral fat in middle-aged and older adults. PloS one. 2015;10(3):e0120354.
17. Archundia-Herrera C, Macias-Cervantes M, Ruiz-Muñoz B, Vargas-Ortiz K, Kornhauser C, Perez-Vazquez V. Muscle irisin response to aerobic vs HIIT in overweight female adolescents. Diabetology & metabolic syndrome. 2017;9(1):101.
18. Gibala MJ, McGee SL. Metabolic adaptations to short-term high-intensity interval training: a little pain for a lot of gain? Exercise and sport sciences reviews. 2008;36(2):58-63.
19. Korkmaz S, Goksuluk D, Zararsiz G. MVN: an R package for assessing multivariate normality. The R Journal. 2014;6(2):151-62.
20. Norheim F, Langleite TM, Hjorth M, Holen T, Kielland A, Stadheim HK, et al. The effects of acute and chronic exercise on PGC‐1α, irisin and browning of subcutaneous adipose tissue in humans. The FEBS journal. 2014;281(3):739-49.
21. Huh JY, Panagiotou G, Mougios V, Brinkoetter M, Vamvini MT, Schneider BE, et al. FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism-Clinical and experimental. 2012;61(12):1725-38.
22. Timmons JA, Baar K, Davidsen PK, Atherton PJ. Is irisin a human exercise gene? Nature. 2012;488(7413):E9.
23. Hecksteden A, Wegmann M, Steffen A, Kraushaar J, Morsch A, Ruppenthal S, et al. Irisin and exercise training in humans–results from a randomized controlled training trial. BMC medicine. 2013;11(1):235.
24. Jameel F, Thota R, Wood L, Plunkett B, Garg M. Sex-dependent association between circulating irisin levels and insulin resistance in healthy adults. Journal of Nutrition & Intermediary Metabolism. 2015;2(3-4):86-92.