The effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 protein levels of visceral fat in rats fed a high-fat diet

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran

2 Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Aim:      The purpose of the present study is to investigate the effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 training and visceral improvement in diets fed with a high-fat diet. Methods: Twenty-four male Wistar rats were randomly divided into four groups: standard diet (ND) (6), high-fat diet (HFD) (6), high-fat diet with high-intensity interval training (HFD+HIIT) (6), high-fat diet with moderate intensity continuous training (HFD+MICT) (6). The HIIT and MICT groups participated in sports activities specific to their group for 8 weeks, 5 sessions per week. CTRP-3 protein levels were measured using western blot method. The data were analyzed using ANOVA and Tukey's tests. Results: The findings showed that the high-fat diet led to a significant decrease in visceral fat CTRP-3 compared to the standard diet group (P=0.002). In contrast, both groups of HIIT and MICT training led to a significant increase in visceral fat CTRP-3 compared to the high-fat diet group (P=0.029, P=0.004). However, there was no significant difference between the training groups (P<0.05). Conclusions: High-intensity intermittent and moderate-intensity continuous training can reverse the negative effects induced by a high-fat diet on CTRP-3, which may play an important role in improving insulin resistance through this process.

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Main Subjects

References

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                Guo B, Zhuang T, Xu F, Lin X, Li F, Shan S-K, et al. New insights into implications of CTRP3 in obesity, metabolic dysfunction, and cardiovascular diseases: potential of therapeutic interventions. Frontiers in Physiology. 2020;11:570270.

Journal of Applied Health Studies in Sport Physiology
Volume 11, Issue 2
August 2024
Pages 93-105

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History

  • Receive Date: 29 January 2024
  • Revise Date: 09 May 2024
  • Accept Date: 10 May 2024

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