Investigating the effect of a period of resistance training on the serum levels of FGF6 and MyoD in middle-aged men and women

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Department of Physical Education and Sports Sciences, University of Lorestan, Khorramabad,, Iran

2 Dept. of Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khorramabad, Iran

Abstract

Aim:  It seems that people under the influence of the secretion of some growth factors benefit from different training adaptations in terms of developing strength and increasing muscle mass. Therefore, this study aims to investigate the effect of 12 weeks of resistance training on the serum levels of FGF6 and MyoD in middle-aged men and women. Methods:  In a semi-experimental study, 40 middle-aged men and women in Arak City (age: 38.27±6.03 years, weight: 77.12±11.28 kg, height: 174.05±7.24 cm) were randomly selected and placed in two experimental groups (n: 30) and control (n: 10). The training program included 12 weeks of resistance training in 3 sessions per week with an intensity of 65-80% of one repetition maximum (1RM).  Blood sampling was done in 4 periods, before training and following it in the 4th, 8th, and 12th week of training, and the serum concentration of FGF-6 and MyoD were measured by the ELISA method. After checking the normality of the data, a repeated measure one-way ANOVA, and Bonferroni's post hoc test were used at a significance level of P<0.05. Results:  Resistance training in all three training periods (weeks 4, 8, and 12) caused a significant increase in the serum concentration of FGF6 (P=0.001), the serum concentration of MyoD (P=0.001), and these changes coincided with the improvement of the maximum strength of the participants. Also, exercise decreased body fat percentage (P=0.021) in middle-aged men and women. Conclusions:  Performing resistance exercises can have positive effects on the plasma levels of FGF6 and MYoD in elderly men and women, due to the direct relationship between FGF6 and MyoD with increasing maximum strength, it is suggested that trainers and sports experts pay special attention to the necessity of performing resistance exercises in the design of various sports exercises

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References

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Journal of Applied Health Studies in Sport Physiology
Volume 11, Issue 2
August 2024
Pages 68-81

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History

  • Receive Date: 17 December 2023
  • Revise Date: 24 April 2024
  • Accept Date: 25 April 2024

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