The effect of 8 weeks of intense resistance training on serum levels of perpetin, atropine and insulin hormone in obese men with prediabetes

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Master's student in sports physiology and health, Faculty of Humanities, University of Kashan, Kashan, Iran

2 Department of Physical Education and Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.

3 Ph.D in Exercise physiology, educational sciences and psychology, University of Mohaghegh Ardabili, Iran

Abstract

Aim: Cytokines preptin and adropin have a regulatory role in energy metabolism, but their mechanism in response to exercise in obese prediabetic subjects is not well understood. The aim of this study was to investigate the effect of 8 weeks of intense circuit resistance training on serum levels of preptin and adropin in obese men with prediabetes. Method: In this semi-experimental study, 30 obese prediabetic men were randomly divided into two experimental and control groups (15 people in each group). The experimental group participated in the HIRT program with an intensity of 80-85% of one maximum repetition for 8 weeks and three sessions for 60 minutes each week. Serum levels of adropin, preptin, and insulin were measured on two occasions before and after the test. Data analysis was done using independent t test and paired t test at a significance level of P<0.05. Results: The levels of preptin (P=0.002), insulin (P=0.007), glucose (P=0.001), insulin resistance (P=0.001) decreased significantly in the experimental group compared to the control group. While the level of adropin showed a significant increase (P=0.003). Paired t results showed a significant decrease in preptin (P=0.001, -0.20 percent), an increase in adropin (P=0.001, 21.5 percent), and a decrease in indicators related to diabetes insulin (P = 0.001) P, -17.5 percent), glucose (P=0.001, -19.1 percent) and insulin resistance (P=0.001, -17.5 percent) in response to the exercise protocol (P<0.05). Conclusion: Probably, HIRT exercises can have a beneficial effect on adropin, preptin and some diabetes indicators and body composition in pre-diabetic obese men.

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Main Subjects

References

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Journal of Applied Health Studies in Sport Physiology
Volume 11, Issue 2
August 2024
Pages 54-67

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History

  • Receive Date: 11 January 2024
  • Revise Date: 16 March 2024
  • Accept Date: 17 March 2024

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