Effects of combined exercise on serum kinesin-1 levels and physical performance in elderly men with type 2 diabetes

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Master’s Student, Faculty of Humanities, Alborz University, Abyek, Iran

2 Phd in Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran

3 Assistant Professor, Department of Physical Education and Sports Science, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran.

Abstract

Aim:      Type 2 diabetes is a condition that leads to impaired axonal transport, and exercise can lead to its improvement. However, the mechanisms and effects of exercise in these disorders still need to be fully understood. This study aimed to examine the effect of combined exercises on serum kinesin-1 and the physical performance of older men with type 2 diabetes. Method:   In this clinical semi-experimental study, 16 older men with diabetes (age: 67.07 ± 1.50 years) were randomly divided into two control groups and aerobic resistance training groups. The exercises were done for eight weeks and three sessions per week for 90 minutes. Kinesin-1 blood variable and performance  physical  were measured 48 hours before and after training. Paired t-test was used to check intra-group changes, and the ANCOVA test was used to check the difference between groups. All statistical calculations were performed using SPSS version 23 software at a significance level of P<0.05.Results: Paired t-test shows that in the training group, kinesin-1 values (t = 4.14, P = 0.08) decreased, lower body strength (t = 2.26, P = 0.01) significantly increased, and aerobic endurance values ( t=5.15, P=0.07) and upper body strength (t=1.80, P=0.09) increased after the intervention. Intergroup analysis showed a significant increase in aerobic endurance values (P=0.006, F=11.80) and lower body strength (P=0.01, F=10.80). Also, the levels of kinesin-1 (P=0.07, F=61.23) decreased, and upper body strength increased (P=0.08, F=8.70), but they were not significant. Conclusion: According to the results of prescribing combined exercises in The elderly with type 2 diabetes, it can have the most excellent effect on improving functional indices and improving kinesin-1 values in diabetic elderly.Conclusion:  Prescribing combined exercises in the elderly with type 2 diabetes has probably improved  physical performance and kinesin-1 levels in the elderly with diabetes

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Main Subjects


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