The effect of Six weeks of High intensity interval training with fenugreek supplementation on plasma levels of malondialdehyde and glutathione peroxidase in overweight and obese women

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Faculty of Sport Sciences, University of Birjand

2 Depatrment of Sport Sceinces, Faculty of Sport Sciences, University of Birjand

Abstract

Aim:  Despite the positive effects of HIIT training but it causes oxidative stressdue to high intensity; Therefore, the aim of this study was to investigate the effect of 6 weeks of High intensity interval training with fenugreek supplementation on plasma levels of malondialdehyde and glutathione peroxidase of obese and overweight women.  Methods:  Accordingly 48 obese and overweight women with age average of 29.79± 7/8 years and a body mass index of 29.29 ± 2.6 kg / m2 were purposefully selected and randomly divided into 4 groups of 12. Individuals received exercise + placebo, exercise + supplement, supplement and placebo. supplement consuming groups consumed 500 mg fenugreek capsule daily for 6 weeks. The training groups performed an exercise protocol of HIIT training with maximum speed during 6 weeks  and three session per week. Blood samples were taken 48 hours before and  48 hours after the training period and  supplement consumption, and ELISA method was used to measure the research variables. Statistical analysis of data was performed by analysis of covariance and Scheffe post hoc tests at a significance level of P<0.05. Result:: Significant decrease in malondialdehyde in exercise + supplement group (P = 0.048) compared to placebo group and significant increase in  exercise + placebo groups (p = 0.0001),  exercise + supplement (p = 0.0001)  and supplement groups (p=0/0001) were seen compared to the placebo groups But no significant difference was observed between the other groups.  Conclusion: Fenugreek consumption along with regular High intensity interval training is a more appropriate intervention to improve the antioxidant status of obese or overweight people.

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This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

References

  1. 1. Bhupathiraju SN, Hu FB. Epidemiology of obesity and diabetes and their cardiovascular complications. Circulation research. 2016;118(11):1723-35.
  2. 2. Bastien M, Poirier P, Lemieux I, Després J-P. Overview of epidemiology and contribution of obesity to cardiovascular disease. Progress in cardiovascular diseases. 2014;56(4):369-81.
  3. 3. Bahrami A, Saremi A. Effect of caloric restriction with or without aerobic training on body composition, blood lipid profile, insulin resistance, and inflammatory marker in middle-age obese/overweight men. Arak Medical University Journal. 2011;14(3):11-9. [In Persian]
  4. 4. Emami A-M, Homaee HM, Azarbayjani MA. Effects of high intensity interval training and curcumin supplement on glutathione peroxidase (GPX) activity and malondialdehyde (MDA) concentration of the liver in STZ induced diabetic rats. Iranian Journal of Diabetes and Obesity. 2016;8(3):129-34. [In Persian]
  5. 5. Gholizadeh S, Moghimbeigi A, Poorolajal J, Khjeian M, Bahramian F. Study of risk factors affecting both hypertension and obesity outcome by using multivariate multilevel logistic regression models. ISMJ. 2016;19(3):385-97. [In Persian]
  6. 6. Jahani GR, Firouzrai M, Matin HH, Tarverdizadeh B, Azarbaijani MA, Movaseghi GR, et al. The effect of continuous and regular exercise on erytrocyte antioxidative enzymes activity and stress oxidative in young soccer players. 2010. . [In Persian]
  7. 7. Brown NC, Andreazza AC, Young LT. An updated meta-analysis of oxidative stress markers in bipolar disorder. Psychiatry Research. 2014;218(1-2):61-8.
  8. 8. Martinovic J, Dopsaj V, Kotur-Stevuljevic J, Dopsaj M, Vujovic A, Stefanovic A, et al. Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. The Journal of Strength & Conditioning Research. 2011;25(5):1360-7.
  9. 9. Soslu R, Özer Ö, Çuvalcioglu IC. The Effects of Core Training on Basketball Athletes' Antioxidant Capacity. Journal of Education and Training Studies. 2018;6(11):128-34.
  10. 10. Wang D, Wang J, Liu Y, Zhao Z, Liu Q. Roles of Chinese herbal medicines in ischemic heart diseases (IHD) by regulating oxidative stress. International Journal of Cardiology. 2016;220:314-9.
  11. 11. Deaton CM, Marlin DJ. Exercise-associated oxidative stress. Clinical Techniques in Equine Practice. 2003;2(3):278-91.
  12. 12. Afzalpour ME, Taheri Chadourneshin H. Physical Activity and Oxidative Stress. Tehran: Bamdad Ketab; 2014.
  13. 13. Powers SK, Jackson MJ. Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiological reviews. 2008;88(4):1243-76.
  14. 14. Shadkam T, Nazarali P, Bijeh N. The effect of aerobic exercises combined with curcuma longa supplementation on cardiovascular inflammatory indexes and body composition in sedentary women. Journal of Sport Biosciences. 2016;8(2):193-206. [In Persian]
  15. 15. Tewari D, Jóźwik A, Łysek-Gładysińska M, Grzybek W, Adamus-Białek W, Bicki J, et al. Fenugreek (Trigonella foenum-graecum L.) Seeds Dietary Supplementation Regulates Liver Antioxidant Defense Systems in Aging Mice. Nutrients. 2020;12(9):2552.
  16. Zeweil HS, Zahran SM, Abd El-Rahman MH, El-Gindy Y, Embark J. Effect Of Fenugreek And Anise Seeds As Natural Growth Promoter On The Performance, Carcass, Blood Constituents And Antioxidant Status Of Growing Rabbits. Egyptian Poultry Science Journal. 2015;35(4).
  17. 17. Chatraei Azizabadi M, Nazarali P, Hedayati M, Ramezankhani A. The Effect of 6-Week Pilates Exercise and Fenugreek Supplement on Total Antioxidant Capacity and Mineral Content in Active Women. The Horizon of Medical Sciences. 2019;25(3):158-71. [In Persian]
  18. 18. Kassaee SM, Goodarzi MT, Oshaghi EA. Antioxidant, antiglycation and anti-hyperlipidemic effects of Trigonella foenum and Cinnamon in type 2 diabetic rats. Jundishapur J Nat Pharm Prod. 2018;13(1):e38414. [In Persian]
  19. 19. Lee S, Birukov KG, Romanoski CE, Springstead JR, Lusis AJ, Berliner JA. Role of phospholipid oxidation products in atherosclerosis. Circulation research. 2012;111(6):778-99.
  20. 20. Kumar P, Bhandari U. Protective effect of Trigonella foenum-graecum Linn. on monosodium glutamate-induced dyslipidemia and oxidative stress in rats. Indian Journal of Pharmacology. 2013;45(2):136.
  21. 21. Buchan DS, Ollis S, Young JD, Thomas NE, Cooper SM, Tong TK, et al. The effects of time and intensity of exercise on novel and established markers of CVD in adolescent youth. American Journal of Human Biology. 2011;23(4):517-26.
  22. 22. Modir M, Daryanoosh F, Mohamadi M, Firouzmand H. The effects of short and middle times aerobic exercise with high intensities on ingredients antioxidant in female Sprague Dawley rats. medical journal of mashhad university of medical sciences. 2014;57(3):587-95. [In Persian]
  23. 23. Ji LL. Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling. Free Radical Biology and Medicine. 200
Journal of Applied Health Studies in Sport Physiology
Volume 9, Issue 2
August 2022
Pages 213-226

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History

  • Receive Date: 04 January 2023
  • Accept Date: 04 January 2023

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