The Effect of 8 Weeks High Intensity Interval Training and Moderate-Intensity Continuous Training on Plasma GDF-15, Troponin and hs-CRP in Obese Young Men

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 MS in Exercise Physiology, Faculty of Exercise Physiology and Sport Sciences, University of Sistan and Baluchestan, Zahedan, Iran

2 Associate Professor, Department of Sport Sciences, University of Sistan and Baluchestan, Zahedan, Iran

3 Assistant Professor, Department of Exercise Physiology, Sport Sciences Research Institute, Tehran, Iran

Abstract

Aim: The aim of this study was to investigate the effect of 8 weeks high intensity interval training (HIIT) and moderate intensity continuous training (MICT) on plasma GDF-15, troponin and hs-CRP in young fat males. Methods: 45 obese youth males (BMI≥30) were selected purposefully and divided into three groups of HIIT (15 patients), MICT (15 patients) and control (15 people). Blood samples were taken from all subjects after 10 hours of overnight fasting in two stages: 1. 24 hours before starting the training program, 2. 48 hours after the last exercise session. Data analysis was done by one-way ANOVA test with Tukey post-hoc test and dependent T test. All statistical analysis was done at a significant level of P≤0.05 by SPSS software version 20. Results: Based on the results, plasma levels of GDF-15, troponin I and CRP in JIIT group showed a significant difference compared to the control group (P <0.05). Plasma levels of GDF-15 and CRP also changed significantly in the MICT group (P <0.05), but troponin I level did not change significantly (P> 0.05). Also, there was no significant difference between the effect HIIT and MICT on plasma GDF-15 and CRP levels (P> 0.05). Conclusion: HIIT and MICT improved the plasma levels of GDF-15 and CRP in obese young men. However, the Troponin I index only decreased following HIIT. Therefore, the beneficial effects of HIIT are likely to be more pronounced in improving cellular injury markers.

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