The Functional Response, Immune System and Hormonal Levels of The Military to Short-Term Sleep Deprivation with Different Times

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Msc of Exercise Physiology, Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Rasht, Iran.

2 Msc of Exercise Physiology, Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, University of Kharazmi, Tehran, Iran.

3 Msc of Exercise Physiology, Department of Physical Education of the Armed Forces, Army College of the Islamic Republic of Iran, Tehran-Iran.

Abstract

Aim: Sleep deprivation is more common in military personnel due to missions and military operations, and they are scheduled to be deprived of sleep at special times at night posts, respectively. However, sleep deprivation has effects negative and irreversible. Therefore, the purpose of the present study was to investigate the functional response, immune system and hormonal levels of the military to short-term sleep deprivation at different times of the night. Methods: The present study began with the purposeful and voluntary selection of 40 healthy military personnel, they were randomly divided into 4 groups (Group 1: Deprivation from 12am to 2am; Group 2: Deprivation from 2am to 4am, Group 3: Deprivation from 4am to 6am and Group 4: control group). Each group was evaluated in two stages before and after sleep deprivation. Results: There was a significant difference in pre and post-test sleep deprivation hours 12am to 2am static and dynamic balance, auditory and visual reaction time. Also, in deprivation hours 2am to 4am significantly changed the auditory and visual reaction time and cortisol. In addition, were increased cortisol and melatonin at time 4am to 6am (p < 0.05). Conclusion: The negative effects of sleep deprivation appear to occur at different dimensions and with different times, but only 12 to 2 deprivation have a deleterious effect on balance and reaction time and 2 to 4 deprivation on reaction time and cortisol.

Keywords

References

1.        Redwine, L., Hauger, R. L., Gillin, J. C., & Irwin, M. (2000). Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans. The Journal of Clinical Endocrinology & Metabolism, 85(10), 3597-3603.
2.        Chandola, T., Ferrie, J. E., Perski, A., Akbaraly, T., & Marmot, M. G. (2010). The effect of short sleep duration on coronary heart disease risk is greatest among those with sleep disturbance: a prospective study from the Whitehall II cohort. Sleep, 33(6), 739-744.
3.        Kim, D. J., Lee, H. P., Kim, M. S., Park, Y. J., Go, H. J., Kim, K. S., ... & Lee, C. T. (2001). The effect of total sleep deprivation on cognitive functions in normal adult male subjects. International Journal of Neuroscience, 109(1-2), 127-137.
4.        Jennings, J. R., Monk, T. H., & Van der Molen, M. W. (2003). Sleep deprivation influences some but not all processes of supervisory attention. Psychological Science, 14(5), 473-486.
5.        Goh, V. H. H., Tong, T. Y. Y., Lim, C. L., Low, E. C. T., & Lee, L. K. H. (2001). Effects of one night of sleep deprivation on hormone profiles and performance efficiency. Military medicine, 166(5), 427-431.
6.        Souissi, N., Sesboüé, B., Gauthier, A., Larue, J., & Davenne, D. (2003). Effects of one night's sleep deprivation on anaerobic performance the following day. European Journal of Applied Physiology, 89(3-4), 359-366.
7.        Leger, D., Metlaine, A., & Choudat, D. (2005). Insomnia and sleep disruption: relevance for athletic performance. Clinics in sports medicine, 24(2), 269-285.
8.        Inoué, S. (1989). Biology of sleep substances. CRC press.
9.        Azboy, O., & Kaygisiz, Z. (2009). Effects of sleep deprivation on cardiorespiratory functions of the runners and volleyball players during rest and exercise. Acta Physiologica Hungarica, 96(1), 29-36.
10.     Bougard, C., Lepelley, M. C., & Davenne, D. (2011). The influences of time-of-day and sleep deprivation on postural control. Experimental brain research, 209(1), 109-115.
11.     Reilly, T., Atkinson, G., Edwards, B., Waterhouse, J., Farrelly, K., & Fairhurst, E. (2007). Diurnal variation in temperature, mental and physical performance, and tasks specifically related to football (soccer). Chronobiology international, 24(3), 507-519.
12.     Karacabey, K., Saygin, O., Ozmerdivenli, R., Zorba, E., Godekmerdan, A., & Bulut, V. (2005). The effects of exercise on the immune system and stress hormones in sportswomen. Neuroendocrinology Letters, 26(4), 361-366.
13.     Hall, J. E. (2015). Guyton and Hall textbook of medical physiology e-Book. Elsevier Health Sciences.
14.     Moghaddam, A., Ghasemniyan, A., Azad, A., & Ghayeblou, B. (2016). Compare the effect of two-stage tapering and gradual tapering on serum lactate, testosterone and cortisol in male athletes. Journal of Applied Health Studies in Sport Physiology. [In Persian].
15.     Doan, B. K., Newton, R. U., Kraemer, W. J., Kwon, Y. H., & Scheet, T. P. (2007). Salivary cortisol, testosterone, and T/C ratio responses during a 36-hole golf competition. International journal of sports medicine, 28(06), 470-479.
16.     Haneishi, K., Fry, A. C., Moore, C. A., Schilling, B. K., Li, Y., & Fry, M. D. (2007). Cortisol and stress responses during a game and practice in female collegiate soccer players. Journal of strength and conditioning research, 21(2), 583.
17.     Madden, K. S., Sanders, V. M., & Felten, D. L. (1995). Catecholamine influences and sympathetic neural modulation of immune responsiveness. Annual review of pharmacology and toxicology, 35(1), 417-448.
18.     Hui, L., Hua, F., Diandong, H., & Hong, Y. (2007). Effects of sleep and sleep deprivation on immunoglobulins and complement in humans. Brain, behavior, and immunity, 21(3), 308-310.
19.     Wu, H., Dunnett, S., Ho, Y. S., & Chnag, R. C. C. (2019). The role of sleep deprivation and circadian rhythm disruption as risk factors of Alzheimer’s disease. Frontiers in neuroendocrinology, 100764.
20.     Shiravand, F., Ranjbar, R., Ghanbar Zadeh, M., & Hosein Zadeh, M. (2019). The effect of melatonin on anaerobic power and short-term maximal performances in Girls student in Physical Education. Journal of Applied Health Studies in Sport Physiology. [In Persian].
21.     Li, T., Jiang, S., Lu, C., Yang, W., Yang, Z., Hu, W., Xin, Z. and Yang, Y. (2019). Melatonin: Another avenue for treating osteoporosis?. Journal of pineal research, 66(2), 12548.
22.     Hui, L., Hua, F., Diandong, H., & Hong, Y. (2007). Effects of sleep and sleep deprivation on immunoglobulins and complement in humans. Brain, behavior, and immunity, 21(3), 308-310.
23.     Vardar, S. A., Öztürk, L., Kurt, C., Bulut, E., Sut, N., & Vardar, E. (2007). Sleep deprivation induced anxiety and anaerobic performance. Journal of sports science & medicine, 6(4), 532.
24.     Reilly, T. (1990). Human circadian rhythms and exercise. Critical reviews in biomedical engineering, 18(3), 165-180.
25.     Scott, J. P., McNaughton, L. R., & Polman, R. C. (2006). Effects of sleep deprivation and exercise on cognitive, motor performance and mood. Physiology & behavior, 87(2), 396-408.
26.     Van Dongen, H., Maislin, G., Mullington, J. M., & Dinges, D. F. (2003). The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep, 26(2), 117-126.
27.     Pierre, P. & et al(2005). “Accident Analysis and Prevention”. Sleep Medicine, (37): 473- 478.
28.     Rognum, T. O., Vartdal, F., Rodahl, K., Opstad, P. K., Knudsen-baas, O., Kindt, E., & Withey, W. R. (1986). Physical and mental performance of soldiers on high-and low-energy diets during prolonged heavy exercise combined with sleep deprivation. Ergonomics, 29(7), 859-867.
29.     Philip, P., Sagaspe, P., Moore, N., Taillard, J., Charles, A., Guilleminault, C., & Bioulac, B. (2005). Fatigue, sleep restriction and driving performance. Accident Analysis & Prevention, 37(3), 473-478.
30.     Caldwell, J. A., Prazinko, B., & Caldwell, J. L. (2003). Body posture affects electroencephalographic activity and psychomotor vigilance task performance in sleep-deprived subjects. Clinical Neurophysiology, 114(1), 23-31.
31.     Harrison, Y., & Horne, J. A. (2000). Sleep loss and temporal memory. The Quarterly Journal of Experimental Psychology: Section A, 53(1), 271-279.
32.     Reilly, T., & Deykin, T. (1983). Effects of partial sleep loss on subjective states, psychomotor and physical performance tests. Journal of Human Movement Studies, 9, 157-170.
33.     Vardar, S. A., Öztürk, L., Kurt, C., Bulut, E., Sut, N., & Vardar, E. (2007). Sleep deprivation induced anxiety and anaerobic performance. Journal of sports science & medicine, 6(4), 532.
34.     Waddington, I., & Smith, A. (2013). Sport, health and drugs: A critical sociological perspective. Routledge.
35.     Morad, Y., Azaria, B., Avni, I., Barkana, Y., Zadok, D., Kohen-Raz, R., & Barenboim, E. (2007). Posturography as an indicator of fatigue due to sleep deprivation. Aviation, space, and environmental medicine, 78(9), 859-863.
36.     Winter, D. A., Patla, A. E., Prince, F., Ishac, M., & Gielo-Perczak, K. (1998). Stiffness control of balance in quiet standing. Journal of neurophysiology, 80(3), 1211-1221.
37.     Shu, Z., Xing-Yu, W., & Li-Ping, H. A. N. (1997). Effect of sleep deprivation up to 48-hour on tracking performance and two-hand accordance. Chine Journal of Aerospace Medicine, 8, 158-162.
38.   Nielson, C. A., Deegan, E. G., Hung, A. S., & Nunes, A. J. (2010). Potential effects of sleep deprivation on sensorimotor integration during quiet stance in young adults. Western Undergraduate Research Journal: Health and Natural Sciences, 1(1).
39.   Karimipour, A. (2013). The effect of sleep and insomnia on performance indices of elite futsal women in Khuzestan province. Second International Congress of Science and Football, the First Football Theses Festival. [In Persian].
40.     Arazi, H., Asadi, A., Hoseini, K., Mohammad Zade Salamat, K., & Piri Kord, K. (2011). The Effects of a 30-hour Sleep Deprivation on Reaction Time, Neuromuscular Coordination and Aerobic Capacity in Non-athlete Male Students. The Horizon of Medical Sciences, [In Persian].
41.     Emet, M., Ozcan, H., Ozel, L., Yayla, M., Halici, Z., & Hacimuftuoglu, A. (2016). A review of melatonin, its receptors and drugs. The Eurasian journal of medicine, 48(2), 135.
42.     McMorris, T., Harris, R. C., Howard, A. N., Langridge, G., Hall, B., Corbett, J., ... & Hodgson, C. (2007). Creatine supplementation, sleep deprivation, cortisol, melatonin and behavior. Physiology & behavior, 90(1), 21-28.
43.     Scheer, F. A., & Czeisler, C. A. (2005). Melatonin, sleep, and circadian rhythms. Sleep medicine reviews, 9(1), 5-9.
44.     Martin, B. J., Bender, P. R., & Chen, H. I. (1986). Stress hormonal response to exercise after sleep loss. European journal of applied physiology and occupational physiology, 55(2), 210-214.
45.     O'Connor, P. J., Morgan, W. P., Koltyn, K. F., Raglin, J. S., Turner, J. G., & Kalin, N. H. (1991). Air travel across four time zones in college swimmers. Journal of Applied Physiology, 70(2), 756-763.
46.     Mougin, F., Bourdin, H., Simon-Rigaud, M. L., Nhu, U. N., Kantelip, J. P., & Davenne, D. (2001). Hormonal responses to exercise after partial sleep deprivation and after a hypnotic drug-induced sleep. Journal of sports sciences, 19(2), 89-97.
47.     Oztürk, L., Pelin, Z., Karadeniz, D., Kaynak, H., Çakar, L., & Gözükirmizi, E. (1999). Effects of 48 hours sleep deprivation on human immune profile. Sleep Res Online, 2(4), 107-111.
48.     Zager, A., Andersen, M. L., Ruiz, F. S., Antunes, I. B., & Tufik, S. (2007). Effects of acute and chronic sleep loss on immune modulation of rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 293(1), R504-R509.
49.     Ruiz, F. S., Andersen, M. L., Martins, R. C., Zager, A., Lopes, J. D., & Tufik, S. (2012). Immune alterations after selective rapid eye movement or total sleep deprivation in healthy male volunteers. Innate immunity, 18(1), 44-54.
50.     Hui, L., Hua, F., Diandong, H., & Hong, Y. (2007). Effects of sleep and sleep deprivation on immunoglobulins and complement in humans. Brain, behavior, and immunity, 21(3), 308-310.
 
 
 
 
Journal of Applied Health Studies in Sport Physiology
Volume 6, Issue 2
August 2019
Pages 32-39

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History

  • Receive Date: 26 November 2019
  • Revise Date: 18 February 2020
  • Accept Date: 19 February 2020

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