Effect of aerobic exhaustion with six weeks low calorie diet with moderate carbohydrate on lactate dehydrogenase and liver enzymes in overweight boys

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Dept of Exercise Physiology Ahwaz University of Shahid Chamran, Ahwaz, Iran

2 MSc, Department of Business Administration, Islamic Azad University, Ilam Branch, Ilam, Iran

Abstract

Increased lactate dehydrogenase and liver enzymes may be harmf ul to the individual through exercise-induced exhaustion in the blood. Using low-calorie diets with moderate carbohydrates is one of the ways to reduce these amounts.
For this purpose, among overweight boys students studying at Shahid Chamran University, 30 were selected randomly and divided into two experimental and control groups based on body composition index. For experimental group, low calorie diet with moderate carbohydrate (carbohydrate contribution of 55% of energy) was recounted by a 24-hour questionnaire for 6 weeks and adjusted with food nutrition expert's nutrition software. For inter-group variation, t-dependent variation was used to compare the covariance between groups.
The results indicated that serum alkaline phosphatase and lactate dehydrogenase increased significantly with an aerobic exercise session in both experimental and control groups. However, the values of AST and alanine aminotransferase between the two experimental and control groups were not significant at all despite the increase.
A six-week low-calorie diet with moderate carbohydrates can significantly reduce lactate dehydrogenase and liver enzymes.

Keywords

Main Subjects

References

1. Balogh, N., Gaal, T., Ribiczyne, PS., Petri, A.) 2010.( Biochemical and antioxidant changes in plasma and erythrocytes of pentathlon horses before and after exercise. Vet clin pathol. 30(4):214-18.
2. Benjaminov, O., Beglaibter ,N., Gindy, L., Spivak, H., Singer, P., Wienberg ,M., et al. (2007).The effect of a low-carbohydrate diet on the nonalcoholic fatty liver in morbidly obese patients before bariatric surgery. Surg Endosc. 21: 1423-7.
3. Clark, j.( 2006). Weight loss as a treatment for nonalcoholic fatt- y liver disease. J clin gASTroenterol. 40 suppl 1: s39-43.
4. Clarkson, PM., Kearns, AK., Rouzier, O., Rubin, R., Thampson, PD.( 2006).Serum creatine kinas levels and renal function measures in exertional muscle damage. Med Sci Sports Exerc; 38: 623-7.
5. Afshar JafariØ› Majid jahaniØ› Magsoud Zabil Pour. THE EFFECT OF AEROBIC EXERCISE COMBINED WITH SUPPLEMENTATION OF L-ARGININE ON THE RESPONSE OF C-REACTIVE PROTEIN IN OBESE MEN. Biannual Journal of Applied Health Studies in Sport Physiology. Volume 3, Issue 2, Autumn and Winter, 2015, p. 17-23.
6. Garinis, GA., Fruci, B., Mazza, A.(2010). Metformin versus dietary treatment in nonalcoholic hepatic steatosis: a randomized study. Int J Obes;34(8):1255–64.
7. Hallsworth, K., Fattakhova, J., Hollingsworth, KG., Thoma, C., Moore, S.(2011). Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Hepatology. 60(9):1278-83.
8. Hickman, I., Jonsson, J., Prins, J., Ash, S., Purdie, D., Clou- ston, A, et al.( 2004). Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase, fASTing insulin, and quality of life. Gut; 53: 413-9.
9. Khoshbaten, M.( 2009). Comparison character of clinical and laboratory of nonalcoholic fatty liver disease with heALThy people. J Tabib Shargh Sci; P: 13-21.]Persian.
10. Lawlor, DA., Sattar ,N., Smith, GD., Ebrahim, SH.( 2005). The associations of physical activity and adiposity with alanine aminotransferase and gamma-glutamyltransferase. Am J Epidemiol. 161(11): 1081-8
11. Le, TA., Loomba, R.( 2012). Management of Non-alcoholic Fatty Liver Disease and Steatohepatitis”. Journal of Clinical and experimental Hepatology. 2(2):156-73.
12. Liker, M.(2002). Clinical Biochemistry for Medical Sciences students. Ghafari M, Firouzray M. Tehran: Iran University of Medical Sciences Press. p 393.[Persian].
13. Mahaling DU, Basavaraj MM, Bika AJ. Comparison of lipid profile in different grades of non-alcoholic fatty liver disease diagnosed on ultrasound. Asian Pac J Trop Biomed. 2013; 3(11): 907-12.
14. Mougios, V. Exercise Biochemistry.( 2009). Translated by: Nader, Rahnema., Reza, Nouri., Hadi, Rouhani., Saeede, Shadmehri., Neda ,Aghaee., Yaser, Saberi. Tehran, Samt Publishing. [Farsi] .
15. Nikroo, H., Attarzade Hosseini, SR., Sima, H., Nematy, M.( 2011). Effects of diets with or without aerobic exercise program on anthropometric indices and cardiorespiratory fitness in patients with non-alcoholic steatohepatitis. Journal of North Khorasan University of Medical Sciences. 3(3):91-99. [In Persian].
16. Parikh, DJ., Ramanathan, NL.( 1977). Exercise induced serum enzyme changes in untrained subjects. Indian J Physiol Pharmacol. 21: 175-80
17. Park, HS., Kim, MW., Shin, ES.( 1995). Effect of weight control on hepatic abnormalities in obese patients with fatty liver. J Korean Med Sci. 10: 414-21.
18. Petersen, K., Dufour, S., Befroy, D., Lehrke, M., Hendler, R., Shulman ,G.( 2005). Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by mod- erate weight reduction in patients with type 2 diabetes. Diabetes. 54: 603-8 .
19. Radak, Z., chung, HY., Goto, S. (2007). Systemic adaptation to oxidative challenge induced by regular exercise. Free radic Biol Med. 44 (2):153-9
20. Ravanshad, S., Amirkalali, B., Saberfirozi, M., Zare, N., Ma- ram, E.( 2005). Therapeutic effects of restricted diet in obese patients with Non-alcoholic Fatty Liver Disease (NA- FLD). Pak J Med Sci; 21: 472-
21. Narges Ali NiyaØ› Ramin ShabaniØ› Abdolreza Ali Akbari. Comparison of the effects of plyometric and resistance circuit training on body mass index and physical fitness of male teenage student volleyball players. Biannual Journal of Applied Health Studies in Sport Physiology. Volume 3, Issue 1, Autumn and Winter, 2015, p. 104-114.
22. Sirvan AtashakØ› Jamal Rasoul PourØ› Kamal Aziz Beigi. The Effect of progressive resistance training on some cardiovascular risk factors in inactive men. Biannual Journal of Applied Health Studies in Sport Physiology. Volume 3, Issue 1, Autumn and Winter, 2015, p. 58-71.
23. Vozarova, B., Stefan, N., Lindsay, RS., Saremi, A., Pratley, RE., Bogardus, C., et al.( 2002). High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes. Jun; 51(6): 1889-95.
24. Westerbacka, J., Lammi, K., Hakkinen, A., Rissanen, A., Salminen,I., Aro, A., et al.( 2005). Dietary fat content modifies liver fat in overweight non diabetic subjects. J Clin Endocrinol Metab. 90: 2804-9 .
25. Wyse, C., Cathcart, A., Sutherland, R., Ward, S., McMillan, L., Gibson, G., et al.( 2005). Effect of maximal dynamic exercise on exhaled ethane and carbon monoxide levels in human, equine and canine athletes. Comp Biochem physiol A Mol Intgr physiol. 141(2): 239-246
26. Wyse, C., Cathcart, A., Sutherland,R., Ward, S., McMillan, L., Gibson, G., et al.( 2005). Effect of maximal dynamic exercise on exhaled ethane and carbon monoxide levels in human, equine and canine athletes. Comp Biochem physiol A Mol Intgr physiol. 141(2): 239-246
27. Zare Derisi, F., Rastegar, L., Hosseini, S., Daneshmandi, H., Choobineh A.,Mohammadbeigi, A.(2014). Correlation of Astrand and ACSM Protocols in Estimating the Maximum Aerobic Capacity (Vo2-Max). Journal of Ergonomics, Vol. 1, No. 3 : 27-35

Files

History

  • Receive Date: 26 May 2019
  • Revise Date: 02 June 2019
  • Accept Date: 23 June 2019

Share

How to cite

Statistics