The Effect of 12 Weeks of Resistance Exercise on Serum Cardiotrophin-1 Levels, Left Ventricular Hypertrophy and Blood Pressure in Hypertensive Elderly Women

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Department of Exercise Physiology, Faculty of Education and Psychology, University of Shiraz, Shiraz, Iran

2 MSc in exercise physiology, Department of Exercise Physiology, Faculty of Education and Psychology, University of Shiraz, Shiraz, Iran

3 PhD Condidate in exercise physiology, Department of Exercise Physiology, Faculty of Education and Psychology, University of Shiraz, Shiraz, Iran

4 Faculty of physical education and Sport Sciences, University of Guilan, Rasht. Iran

Abstract

One of the factors that influences the occurrence of pathological hypertrophy is the molecule cardiotrophin-1 (CT-1) molecule. The purpose of the present study was to investigate the effect of 12 weeks of resistance exercise on serum cardiotrophin-1 levels, left ventricular hypertrophy and blood pressure in hypertensive elderly women.

The subjects who voluntarily participated in the present study were chosen among elderly women who were suffering from hypertension. Therefore, 40 elderly women aged 50 to 70 years old were divided into two groups (control and experimental) based on body fat(20 pessnt) percentage and body mass(26kh.m2) index. The training program consisted of performing resistance exercises three times a week for 12 weeks. The control group had no training program during this period.

According to the results, there was a significant difference between pretest-posttest cardiotrophin-1 (P=0.02) or diastolic blood pressure in the resistance exercise group (P=0.04). A significant difference was also observed between left ventricular wall thickness of post-tests (P=0.01).

The increased levels of cardiotrophin-1 in this study is most probably influenced by the time of performing physical exercise in the long term. The resistance exercise has led to increased levels of cardiotrophin-1 which can be very effective in the cardiac reconstruction and hypertrophy.

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References

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History

  • Receive Date: 03 March 2017
  • Revise Date: 10 July 2017
  • Accept Date: 07 August 2017

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