Effect of aquatic training on serum Fetuin-A, ANGPTL4 and FGF21 levels in type 2 diabetic obese women

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 PhD in Sports Physiology, Urmia University, Faculty of Sports Sciences, Urmia University, Urmia, Iran.

2 Associate Professor of Sports Physiology, Department of Sports Science, Faculty of Humanities ,University of Maragheh, Maragheh, Iran.

Abstract

Aim: Some hepatokines e.g. Fetuin-A, ANGPTL4 and FGF21 are considered as potential factors for type 2 diabetes disorders treatment. The aim of this study was to investigate effects of 12 weeks of aquatic exercise on some serum fetuin-A, ANGPTL4 and FGF21 levels in obese women with type 2 diabetes. Methods: For this purpose, 44 diabetic women aged 50-60 years with a body mass index higher than 25 kg / m2 were randomly divided into two groups of control (n = 22) and water exercise (n = 22). The training group performed underwater exercises for 12 weeks three sessions a week at 75-60% of MHR. The control group followed the normal process of daily activities. Blood samples were collected before and after exercise. Fasting serum glucose, insulin, plasma hemoglobin, fetuin-A, angiopoietin-4, fibroblast growth factor-21, and lipid profile to calculate insulin resistance index. Data were analyzed using ANCOA test. Results: Serum levels of FBS, HbA1C, fetuin-A, ANGPTL4, fat percentage, insulin and insulin resistance in the experimental group decreased significantly after 12 weeks of water training compared to the control group (p<0.05). Also, exercise in water significantly increased FGF21 levels in the experimental group compared to the control group (p<0.05). Exercise in water significantly reduced TC, TG and LDL indices in the experimental group (p<0.05); But the increase in HDL was not significant (p = 0.21). Conclusion: It seems that aquatic could reduce diabetes complications.

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Main Subjects

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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Journal of Applied Health Studies in Sport Physiology
Volume 8, Issue 2
August 2021
Pages 51-60

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History

  • Receive Date: 02 October 2021
  • Revise Date: 25 October 2021
  • Accept Date: 30 October 2021

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