The effect of intense intermittent exercise on plasma levels of myostatin and IGF-1 in obese adolescents

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Assistant Professor, Department of Physical Education, Imam Ali (AS) University, Tehran, Iran.

2 Assistant Professor, Department of Physical Education, Amin University of Law Enforcement Sciences, Tehran, Iran.

3 Ph.D. Student, Faculty of Sport Sciences, Islamic Azad University, Karaj Branch

Abstract

Aim:   Myostatin and insulin-like growth factor play an important role in responding to muscle contractions, regulating and stimulating muscle metabolism. The aim of this study was to change plasma myostatin and IGF-1 to eight weeks of intense intermittent exercise in obese adolescents.  Methods:  This study was a quasi-experimental study and 28 obese adolescents were randomly divided into experimental and control groups. The experimental group performed a very intense intermittent training protocol for eight weeks and three sessions per week. In order to measure the plasma levels of myostatin and IGF-1, blood samples were taken in two stages in the fasting state, 48 hours before and after exercise. A correlated t-test was used for intra-group comparison and an independent t-test was used for comparison between groups. Results:   The results showed that after eight weeks of very intense interval training, plasma myostatin levels significantly decreased (P=0.001) and IGF-1 (P=0.013) compared to the control group. Conclusion: According to the findings of the present study that a significant reduction of myostatin and the significant increase in IGF-1, high-intensity interval training can be used as a non-pharmacological strategy for prevention and improvement in obese adolescents.

Keywords

Main Subjects

   

 

This is an open access article distributed under the following Creative Commons license: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

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Journal of Applied Health Studies in Sport Physiology
Volume 8, Issue 2
August 2021
Pages 18-24

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History

  • Receive Date: 22 June 2021
  • Revise Date: 05 August 2021
  • Accept Date: 28 August 2021

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