Effect of two-week exercise and supplementation of royal jelly on total antioxidant capacity of plasma and superoxide dismutase in obese male rats

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 M.SC of Sport Physiology, Faculty of Physical Education and Sport Sciences, Alzahra University, Tehran, Iran

2 Associate Professor of Sport Physiology, Faculty of Physical Education and Sport Sciences, Alzahra University, Tehran, Iran

3 Associate Professor of Biochemistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4 Faculty of physical education, razi univercity, kermanshah, iran

Abstract

Increased production of free radicals during metabolism and physical activity are significant biological changes that oxidative stress in the body can provide background incidence of many diseases. The purpose of this study was to evaluate the effect of 2 week aerobic exercise with royal jelly supplements on Male vistar Rats.
in this study 20 male vistar rats were divided randomly into practice with complementary and non-complementary exercises. Training Program includes 30 minutes of running on a treadmill to exhaustion at a speed of 12 meters per minute and 5 days a week and 300 mg per kg of body weight of royal jelly daily orally supplemented for 2 weeks. the data were analyzed using the Kolmogorov-Smirnov and T-test. The significance level in this study was considered to be 0.05.
The superoxide dismutase and total antioxidant capacity was increased significantly after two week aerobic exercise with royal jelly supplements. This study showed that eating royal jelly reduces oxidative stress.

Keywords

Main Subjects


 
1.             Akova B, Surmen-Gur E, Gur H, Dirican M, Sarandol E, Kucukoglu S. Exercise-induced oxidative stress and muscle performance in healthy women: role of vitamin E supplementation and endogenous oestradiol. European journal of applied physiology. 2001;84(1-2):141-7.
2.             Albert S, Bhattacharya D, Klaudiny J, Schmitzova J, Simuth J. The family of major royal jelly proteins and its evolution. Journal of molecular evolution. 1999;49(2):290-7.
3.             Herbold NH, Visconti BK, Frates S, Bandini L. Traditional and nontraditional supplement use by collegiate female varsity athletes. International journal of sport nutrition and exercise metabolism. 2004;14(5):586-93.
4.             Allesio HM, Hagerman AE. Oxidative steress, exercise and aging. Imperial College Press:. 2006;171.
5.             Bărnuţiu L, Mărghitaş L, Dezmirean D, Mihai C, Bobiş O. Chemical Composition and Antimicrobial Activity of Royal JellyReview Animal Science and Biotechnologies. 2011(2):44.
6.             Block G, Jensen CD, Morrow JD, Holland N, Norkus EP, Milne GL, et al. The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level. Free Radic Biol Med. 2008;45(4):377-84.
7.             Bloodworth BC, Harn CS, Hock CT, Boon YO. Liquid chromatographic determination of trans-10-hydroxy-2-decenoic acid content of commercial products containing royal jelly. Journal of AOAC International. 1995;78(4):1019-23.
8.             Decker EA, Crum AD, Calvert JT. Differences in the antioxidant mechanism of carnosine in the presence of copper and iron. Journal of Agricultural and Food Chemistry. 1992;40(5):756-9.
9.             Kanbur M, Eraslan G, Silici S, Karabacak M. Effects of sodium fluoride exposure on some biochemical parameters in mice: evaluation of the ameliorative effect of royal jelly applications on these parameters. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2009;47(6):1184-9.
10.           Kawashima K, Itoh H, Miyoshi M, Chibata I. Antioxidant properties of branched-chain amino acid derivatives. Chemical & pharmaceutical bulletin. 1979;27(8):1912-6.
11.           Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Molecular biotechnology. 2007;37(1):31-7.
12.           Lobo V, Patil A, Phatak A, Chandra N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy reviews. 2010;4(8):118-26.
13.           Matsui T, Yukiyoshi A, Doi S, Sugimoto H, Yamada H, Matsumoto K. Gastrointestinal enzyme production of bioactive peptides from royal jelly protein and their antihypertensive ability in SHR. The Journal of nutritional biochemistry. 2002;13(2):80-6.
14.           Moradi Z, Shmshky A. The effect of supplementation on changes in levels of superoxide dismutase and catalase saffron during intense aerobic exercise in young women. Research in Sport Sciences
2012(14):119-30.
15.           Nagai T, Nagashima T, Myoda T, Inoue R. Preparation and functional properties of extracts from bee bread. Die Nahrung. 2004;48(3):226-9.
16.           Nagai T, Sakai M, Inoue R, Inoue H, Suzuki N. Antioxidative activities of some commercially honeys, royal jelly, and propolis. 2001.
17.           Ookawara T, Haga S, Ha S, Oh-Ishi S, Toshinai K, Kizaki T, et al. Effects of endurance training on three superoxide dismutase isoenzymes in human plasma. Free radical research. 2003;37(7):713-9.
18.           Kamakura M, Mitani N, Fukuda T, Fukushima M. Antifatigue effect of fresh royal jelly in mice. Journal of nutritional science and vitaminology. 2001;47(6):394-401.
19.           Powers SK, DeRuisseau KC, Quindry J, Hamilton KL. Dietary antioxidants and exercise. Journal of sports sciences. 2004;22(1):81-94.
20.           سلیمانی ش, توفیقی ا, بابایی بناب س. تاثیر 6 هفته تمرین هوازی با مصرف مکمل اسپیرولینا بر شاخص‌های استرس اکسیداتیو در مردان چاق غیرفعال به دنبال یک جلسه فعالیت وامانده ساز. مطالعات کاربردی تندرستی در فیزیولوژی ورزش. 2018;5(2):36-44.
21.           نامنی ف. تاثیر14 روز مکمل سازی با ویتامین C بر عوامل اکسیدانی و آنتی اکسیدانی پس از یک جلسه فعالیت شدید در دختران فعال. مطالعات کاربردی تندرستی در فیزیولوژی ورزش. 2016;3(2):47-55.
22.           Powers SK, Jackson MJ. Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev. 2008;88(4):1243-76.
23.           Radu MD, Schipu, S., Coprean, D. The effect OF cute physical exercise on the antioxidant status of the skeletal and cardiac muscle in the Wistar rat. Romanian Biotechnological Letters. 2010(15):56-62.
24.           Shemshaki A, Ghanbari Nyaky A, Rajabi H, Hedayati M, Slamy F. The effect of intense exercise on antioxidant status Alpine skiers man. Journal of Endocrinology and Metabolism Martyr Beheshti University of Medical Sciences and Health Services. 2007(3):291-7.
25.           Silk DB, Fairclough PD, Clark ML, Hegarty JE, Marrs TC, Addison JM, et al. Use of a peptide rather than free amino acid nitrogen source in chemically defined "elemental" diets. JPEN Journal of parenteral and enteral nutrition. 1980;4(6):548-53.
26.           Starnes JW, Taylor RP. Exercise-induced cardioprotection: endogenous mechanisms. Medicine and science in sports and exercise. 2007;39(9):1537-43.
27.           Takaki-Doi S, Hashimoto K, Yamamura M, Kamei C. Antihypertensive activities of royal jelly protein hydrolysate and its fractions in spontaneously hypertensive rats. Acta medica Okayama. 2009;63(1):57-64.