Effect of two month aerobic training and pomegranate peel extract (PPE) supplementation on Insulin resistance index levels in obese rats

Document Type : Research Paper I Open Access I Released under (CC BY-NC 4.0) license

Authors

1 Department of Physical Education, Tabriz branch, Islamic Azad university, Tabriz, Iran

2 Assistant Professor at Department of Physical Education, Tabriz Branch, Islamic Azad University, Tabriz, Iran

3 Assistant Professor at Department of Veterinary, Tabriz Branch, Islamic Azad university, Tabriz, Iran

Abstract

Introduction & Objectives: The aim of this research was to investigate the Effect of two month aerobic training and pomegranate peel extract (PPE) supplementation on Insulin resistance index in obese rats.
Materials and Methods: Forty aged Wistar rats were randomly divided into four groups including Control, aerobic training (AT), PPE and PPE+ AT. Aerobic training groups participated in 8 weeks of aerobic training, five sessions per week on an automatic treadmill. Administration of pomegranate peel extract (130 gr daily) was done by oral gavage solution method, 20 to 30 minutes before breakfast meal for eight weeks. Blood samples were taken to analyze Insulin resistance index levels and lipid profile and the data were analyzed by descriptive statistics and ANOVA.
Results: The results showed that aerobic training (AT) reduced body weight, insulin and insulin sensitivity, and pomegranate peel extract had no significant effect. However, none of the interventions had a significant effect on plasma glucose.
Conclusion: Exercise alone cannot reduce glucose in obese people, and in order to provide general health in these people, regular exercise programs along with nutritional controls should be introduced to avoid the consumption of simple carbohydrates regardless of physical activity status.

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References

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History

  • Receive Date: 27 January 2020
  • Revise Date: 15 April 2019
  • Accept Date: 21 April 2019

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