Azarbaijan Shahid Madani University Journal of Applied Health Studies in Sport Physiology 2676-6507 11 2 2024 09 22 The effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 protein levels of visceral fat in rats fed a high-fat diet The effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 protein levels of visceral fat in rats fed a high-fat diet 93 105 14768 10.22049/jahssp.2024.29408.1626 FA Marzieh Faramarzi Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran 0009-0007-2401-967x Keyvan Sharifmoradi Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran Zahra Pezeshki Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran Mousa Khalafi Department of Sports Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran 0000-0001-6465-1281 Journal Article 2024 01 29 <strong>Aim</strong>:      The purpose of the present study is to investigate the effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 training and visceral improvement in diets fed with a high-fat diet. <strong>Methods</strong>: Twenty-four male Wistar rats were randomly divided into four groups: standard diet (ND) (6), high-fat diet (HFD) (6), high-fat diet with high-intensity interval training (HFD+HIIT) (6), high-fat diet with moderate intensity continuous training (HFD+MICT) (6). The HIIT and MICT groups participated in sports activities specific to their group for 8 weeks, 5 sessions per week. CTRP-3 protein levels were measured using western blot method. The data were analyzed using ANOVA and Tukey's tests. <strong>Results</strong>: The findings showed that the high-fat diet led to a significant decrease in visceral fat CTRP-3 compared to the standard diet group (P=0.002). In contrast, both groups of HIIT and MICT training led to a significant increase in visceral fat CTRP-3 compared to the high-fat diet group (P=0.029, P=0.004). However, there was no significant difference between the training groups (P<0.05). <strong>Conclusions</strong>: High-intensity intermittent and moderate-intensity continuous training can reverse the negative effects induced by a high-fat diet on CTRP-3, which may play an important role in improving insulin resistance through this process. <strong>Aim</strong>:      The purpose of the present study is to investigate the effect of high-intensity interval training and moderate-intensity continuous training on CTRP-3 training and visceral improvement in diets fed with a high-fat diet. <strong>Methods</strong>: Twenty-four male Wistar rats were randomly divided into four groups: standard diet (ND) (6), high-fat diet (HFD) (6), high-fat diet with high-intensity interval training (HFD+HIIT) (6), high-fat diet with moderate intensity continuous training (HFD+MICT) (6). The HIIT and MICT groups participated in sports activities specific to their group for 8 weeks, 5 sessions per week. CTRP-3 protein levels were measured using western blot method. The data were analyzed using ANOVA and Tukey's tests. <strong>Results</strong>: The findings showed that the high-fat diet led to a significant decrease in visceral fat CTRP-3 compared to the standard diet group (P=0.002). In contrast, both groups of HIIT and MICT training led to a significant increase in visceral fat CTRP-3 compared to the high-fat diet group (P=0.029, P=0.004). However, there was no significant difference between the training groups (P<0.05). <strong>Conclusions</strong>: High-intensity intermittent and moderate-intensity continuous training can reverse the negative effects induced by a high-fat diet on CTRP-3, which may play an important role in improving insulin resistance through this process. https://jahssp.azaruniv.ac.ir/article_14768_83a41c892137bb8cd5e60ad33dbc83ba.pdf