Azarbaijan Shahid Madani University Journal of Applied Health Studies in Sport Physiology 2676-6507 10 2 2023 09 23 The comparison the effect of resistance training versus aerobic training on endothelial function in adults: a systematic review and meta-analysis The comparison the effect of resistance training versus aerobic training on endothelial function in adults: a systematic review and meta-analysis 124 138 14585 10.22049/jahssp.2023.28623.1554 FA Mousa Khalafi University of TehranDepartment of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran 0000-0001-6465-1281 Pejman Taghibeikzadehbadr University of Tehran Eisa Naebi Alamdari MSc in Sports Physiology, Islamic Azad University, Marand Branch, Marand, Iran Journal Article 2023 05 01 <strong>Aim</strong>:    Exercise training leads to the improvement of endothelial function; however, the effect of resistance training versus aerobic exercise on endothelial function is unknown. Therefore, the purpose of this meta-analysis was to investigate the effect of resistance training versus aerobic training on endothelial function in adults.<br />Method: A search was performed in the electronic databases of PubMed, Scopus, Web of Science and Google Scholar until January 13, 2023 for studies of resistance training versus aerobic training on the FMD (flow-mediated dilation) index. The keywords used included "resistance training", "aerobic training" and "endothelial function". Weighted mean difference (WMD) and 95% confidence interval were calculated using CMA2 software in order to determine the effect size.<br />Results:  A total of 12 studies with 473 participants were included to meta-analysis with age and BMI range 21 to 71 years and 24 to 32 kg/m2, respectively. The results of the present meta-analysis showed that both types of resistance and aerobic training lead to an improvement in FMD and there was no significant difference between the two types of training [-0.37 (CI: -1.17 to 0.43), p=0.549]. However, there was a high and significant heterogeneity (I2=61.65, p=0.001).<br />Conclusion: The results of the present study showed that both resistance and aerobic training protocols lead to improvement of endothelial function in adults, which may lead to improvement of cardiovascular function and, subsequently, reduction of cardiovascular diseases induced mortality. <strong>Aim</strong>:    Exercise training leads to the improvement of endothelial function; however, the effect of resistance training versus aerobic exercise on endothelial function is unknown. Therefore, the purpose of this meta-analysis was to investigate the effect of resistance training versus aerobic training on endothelial function in adults.<br />Method: A search was performed in the electronic databases of PubMed, Scopus, Web of Science and Google Scholar until January 13, 2023 for studies of resistance training versus aerobic training on the FMD (flow-mediated dilation) index. The keywords used included "resistance training", "aerobic training" and "endothelial function". Weighted mean difference (WMD) and 95% confidence interval were calculated using CMA2 software in order to determine the effect size.<br />Results:  A total of 12 studies with 473 participants were included to meta-analysis with age and BMI range 21 to 71 years and 24 to 32 kg/m2, respectively. The results of the present meta-analysis showed that both types of resistance and aerobic training lead to an improvement in FMD and there was no significant difference between the two types of training [-0.37 (CI: -1.17 to 0.43), p=0.549]. However, there was a high and significant heterogeneity (I2=61.65, p=0.001).<br />Conclusion: The results of the present study showed that both resistance and aerobic training protocols lead to improvement of endothelial function in adults, which may lead to improvement of cardiovascular function and, subsequently, reduction of cardiovascular diseases induced mortality. https://jahssp.azaruniv.ac.ir/article_14585_71c816d30cf1720f5092ea9f92cd7452.pdf