Azarbaijan Shahid Madani University Journal of Applied Health Studies in Sport Physiology 2676-6507 9 2 2022 09 23 The Effect of a Whole Body Vibration Period on Serum BDNF Levels in Obese Postmenopausal Women The Effect of a Whole Body Vibration Period on Serum BDNF Levels in Obese Postmenopausal Women 81 92 14446 10.22049/jahssp.2022.27795.1465 FA Amir Khosravi assistant professor/ Ayatollah Ozma Borujerdi University Sedigheh Taherzadeh Department of Physical Education, Faculty of Human Sciences, Technical and Vocational University (TVU), Tehran, Iran. Journal Article 2022 05 04 <strong>Aim</strong>:  One of the key factors involved in central nervous system  performance is neurotrophins, including BDNF, which decrease with menopause. The aim of this study was to determine the effect of a whole body vibration period on serum BDNF levels in obese postmenopausal women. <strong>Methods</strong>: In this  semi-experimental study, 24 obese postmenopausal women aged 45-55 years  with an average weight 72/5±5 in Khorramabad city were divided into two groups of 12: 1- without training 2- whole body vibration training. Whole body vibration training group performs these exercises for 12 weeks and three times a week, with a frequency of 30-50 Hz, with an amplitude of 1-2 mm by applying 20 to 30 minutes of vibration, 5 to 15 minutes of upper and lower limb training. 48 hours before the start of the training program and 48 hours after the end of the 12 week training program; Blood sampling and body composition indices were measured. ELISA method was used to measure serum BDNF levels.  Data were analyzed using independent t-test and covariance at the significance level of 0.05. <strong>Results</strong>: Results Significant decrease in morphometric indices such as body fat percentage (P = 0.023), body mass index (P = 0.012), and body weight (P = 0.038), as well as significant increase At serum BDNF levels (P < 0.026), the whole body showed vibration compared to the control group. <strong>Conclusions</strong>: It seems that the beneficial effects of vibration exercises on increasing BDNF can be a factor in reducing the negative effects of menopause on cognitive function, learning and memory, especially spatial memory. <strong>Aim</strong>:  One of the key factors involved in central nervous system  performance is neurotrophins, including BDNF, which decrease with menopause. The aim of this study was to determine the effect of a whole body vibration period on serum BDNF levels in obese postmenopausal women. <strong>Methods</strong>: In this  semi-experimental study, 24 obese postmenopausal women aged 45-55 years  with an average weight 72/5±5 in Khorramabad city were divided into two groups of 12: 1- without training 2- whole body vibration training. Whole body vibration training group performs these exercises for 12 weeks and three times a week, with a frequency of 30-50 Hz, with an amplitude of 1-2 mm by applying 20 to 30 minutes of vibration, 5 to 15 minutes of upper and lower limb training. 48 hours before the start of the training program and 48 hours after the end of the 12 week training program; Blood sampling and body composition indices were measured. ELISA method was used to measure serum BDNF levels.  Data were analyzed using independent t-test and covariance at the significance level of 0.05. <strong>Results</strong>: Results Significant decrease in morphometric indices such as body fat percentage (P = 0.023), body mass index (P = 0.012), and body weight (P = 0.038), as well as significant increase At serum BDNF levels (P < 0.026), the whole body showed vibration compared to the control group. <strong>Conclusions</strong>: It seems that the beneficial effects of vibration exercises on increasing BDNF can be a factor in reducing the negative effects of menopause on cognitive function, learning and memory, especially spatial memory. https://jahssp.azaruniv.ac.ir/article_14446_07b1b25e104ddc33e789d4725c1a9c45.pdf