Azarbaijan Shahid Madani University Journal of Applied Health Studies in Sport Physiology 2676-6507 9 2 2022 09 23 The effect of Six weeks of High intensity interval training with fenugreek supplementation on plasma levels of malondialdehyde and glutathione peroxidase in overweight and obese women The effect of Six weeks of High intensity interval training with fenugreek supplementation on plasma levels of malondialdehyde and glutathione peroxidase in overweight and obese women 213 226 14382 10.22049/jahssp.2022.27673.1444 FA Khatereh Forotan Faculty of Sport Sciences, University of Birjand 0000-0003-4083-0706 Mehdi Mogharnasi Depatrment of Sport Sceinces, Faculty of Sport Sciences, University of Birjand Mohammad Esmaeil Afzalpour Depatrment of Sport Sceinces, Faculty of Sport Sciences, University of Birjand 0000-0001-6468-8498 Journal Article 2023 01 04 <strong>Aim:</strong>  Despite the positive effects of HIIT training but it causes oxidative stressdue to high intensity; Therefore, the aim of this study was to investigate the effect of 6 weeks of High intensity interval training with fenugreek supplementation on plasma levels of malondialdehyde and glutathione peroxidase of obese and overweight women. <strong> Methods</strong>:  Accordingly 48 obese and overweight women with age average of 29.79± 7/8 years and a body mass index of 29.29 ± 2.6 kg / m² were purposefully selected and randomly divided into 4 groups of 12. Individuals received exercise + placebo, exercise + supplement, supplement and placebo. supplement consuming groups consumed 500 mg fenugreek capsule daily for 6 weeks. The training groups performed an exercise protocol of HIIT training with maximum speed during 6 weeks  and three session per week. Blood samples were taken 48 hours before and  48 hours after the training period and  supplement consumption, and ELISA method was used to measure the research variables. Statistical analysis of data was performed by analysis of covariance and Scheffe post hoc tests at a significance level of P<0.05. <strong>Result:</strong>: Significant decrease in malondialdehyde in exercise + supplement group (P = 0.048) compared to placebo group and significant increase in  exercise + placebo groups (p = 0.0001),  exercise + supplement (p = 0.0001)  and supplement groups (p=0/0001) were seen compared to the placebo groups But no significant difference was observed between the other groups. <strong> Conclusion:</strong> Fenugreek consumption along with regular High intensity interval training is a more appropriate intervention to improve the antioxidant status of obese or overweight people. <strong>Aim:</strong>  Despite the positive effects of HIIT training but it causes oxidative stressdue to high intensity; Therefore, the aim of this study was to investigate the effect of 6 weeks of High intensity interval training with fenugreek supplementation on plasma levels of malondialdehyde and glutathione peroxidase of obese and overweight women. <strong> Methods</strong>:  Accordingly 48 obese and overweight women with age average of 29.79± 7/8 years and a body mass index of 29.29 ± 2.6 kg / m² were purposefully selected and randomly divided into 4 groups of 12. Individuals received exercise + placebo, exercise + supplement, supplement and placebo. supplement consuming groups consumed 500 mg fenugreek capsule daily for 6 weeks. The training groups performed an exercise protocol of HIIT training with maximum speed during 6 weeks  and three session per week. Blood samples were taken 48 hours before and  48 hours after the training period and  supplement consumption, and ELISA method was used to measure the research variables. Statistical analysis of data was performed by analysis of covariance and Scheffe post hoc tests at a significance level of P<0.05. <strong>Result:</strong>: Significant decrease in malondialdehyde in exercise + supplement group (P = 0.048) compared to placebo group and significant increase in  exercise + placebo groups (p = 0.0001),  exercise + supplement (p = 0.0001)  and supplement groups (p=0/0001) were seen compared to the placebo groups But no significant difference was observed between the other groups. <strong> Conclusion:</strong> Fenugreek consumption along with regular High intensity interval training is a more appropriate intervention to improve the antioxidant status of obese or overweight people. https://jahssp.azaruniv.ac.ir/article_14382_00c1b007efd87662594474574b8beef4.pdf