Azarbaijan Shahid Madani University Journal of Applied Health Studies in Sport Physiology 2676-6507 7 2 2020 09 22 The Effect of 8 Weeks High Intensity Interval Training and Moderate-Intensity Continuous Training on Plasma GDF-15, Troponin and hs-CRP in Obese Young Men The Effect of 8 Weeks High Intensity Interval Training and Moderate-Intensity Continuous Training on Plasma GDF-15, Troponin and hs-CRP in Obese Young Men 81 88 14149 10.22049/jahssp.2021.26754.1289 FA Abdolhagh Rigi MS in Exercise Physiology, Faculty of Exercise Physiology and Sport Sciences, University of Sistan and Baluchestan, Zahedan, Iran Mohsen Ghofrani Associate Professor, Department of Sport Sciences, University of Sistan and Baluchestan, Zahedan, Iran Masoumeh Helalizadeh Assistant Professor, Department of Exercise Physiology, Sport Sciences Research Institute, Tehran, Iran Journal Article 2020 11 02 <strong>Aim</strong>: The aim of this study was to investigate the effect of 8 weeks high intensity interval training (HIIT) and moderate intensity continuous training (MICT) on plasma GDF-15, troponin and hs-CRP in young fat males. <strong>Methods</strong>: 45 obese youth males (BMI≥30) were selected purposefully and divided into three groups of HIIT (15 patients), MICT (15 patients) and control (15 people). Blood samples were taken from all subjects after 10 hours of overnight fasting in two stages: 1. 24 hours before starting the training program, 2. 48 hours after the last exercise session. Data analysis was done by one-way ANOVA test with Tukey post-hoc test and dependent T test. All statistical analysis was done at a significant level of P≤0.05 by SPSS software version 20. <strong>Results</strong>: Based on the results, plasma levels of GDF-15, troponin I and CRP in JIIT group showed a significant difference compared to the control group (P <0.05). Plasma levels of GDF-15 and CRP also changed significantly in the MICT group (P <0.05), but troponin I level did not change significantly (P> 0.05). Also, there was no significant difference between the effect HIIT and MICT on plasma GDF-15 and CRP levels (P> 0.05). <strong>Conclusion</strong>: HIIT and MICT improved the plasma levels of GDF-15 and CRP in obese young men. However, the Troponin I index only decreased following HIIT. Therefore, the beneficial effects of HIIT are likely to be more pronounced in improving cellular injury markers. <strong>Aim</strong>: The aim of this study was to investigate the effect of 8 weeks high intensity interval training (HIIT) and moderate intensity continuous training (MICT) on plasma GDF-15, troponin and hs-CRP in young fat males. <strong>Methods</strong>: 45 obese youth males (BMI≥30) were selected purposefully and divided into three groups of HIIT (15 patients), MICT (15 patients) and control (15 people). Blood samples were taken from all subjects after 10 hours of overnight fasting in two stages: 1. 24 hours before starting the training program, 2. 48 hours after the last exercise session. Data analysis was done by one-way ANOVA test with Tukey post-hoc test and dependent T test. All statistical analysis was done at a significant level of P≤0.05 by SPSS software version 20. <strong>Results</strong>: Based on the results, plasma levels of GDF-15, troponin I and CRP in JIIT group showed a significant difference compared to the control group (P <0.05). Plasma levels of GDF-15 and CRP also changed significantly in the MICT group (P <0.05), but troponin I level did not change significantly (P> 0.05). Also, there was no significant difference between the effect HIIT and MICT on plasma GDF-15 and CRP levels (P> 0.05). <strong>Conclusion</strong>: HIIT and MICT improved the plasma levels of GDF-15 and CRP in obese young men. However, the Troponin I index only decreased following HIIT. Therefore, the beneficial effects of HIIT are likely to be more pronounced in improving cellular injury markers. https://jahssp.azaruniv.ac.ir/article_14149_7d724c4b10c19cc7656de12e3cec14a1.pdf